PLYX (Polaryx Therapeutics) PB Ratio: 42.64 (As of Jul. 15, 2026)

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PLYX Polaryx Therapeutics Inc PLYX
13 GF Score
Price $2.26
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What is Polaryx Therapeutics PB Ratio?

Polaryx Therapeutics PLYX +2.73% 13 PB Ratio is 42.64 as of Jul. 15, 2026. GuruFocus rates PLYX with a GF Score™ of 13/100. Among 1,228 Biotechnology companies, Polaryx Therapeutics ranks worse than 97.23% on this metric.

The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. As of today (2026-07-15), Polaryx Therapeutics's share price is $2.26. Polaryx Therapeutics's Book Value per Share for the quarter that ended in Mar. 2026 was $0.05. Hence, Polaryx Therapeutics's PB Ratio of today is 42.64.

The historical rank and industry rank for Polaryx Therapeutics's PB Ratio or its related term are showing as below:

PLYX' s PB Ratio Range Over the Past 10 Years
Min: 0   Med: 0   Max: 46
Current: 45.2

During the past 3 years, Polaryx Therapeutics's highest PB Ratio was 46.00. The lowest was 0.00. And the median was 0.00.

PLYX's PB Ratio is ranked worse than
97.23% of 1228 companies
in the Biotechnology industry
Industry Median: 2.895 vs PLYX: 45.20

During the past 12 months, Polaryx Therapeutics's average Book Value Per Share Growth Rate was -4.00% per year.

Back to Basics: PB Ratio


Polaryx Therapeutics  (NAS:PLYX) PB Ratio Explanation

Unlike valuation ratios relative to the earning power such as PE Ratio, PE Ratio without NRI, PS Ratio, Price-to-Operating-Cash-Flow , or Price-to-Free-Cash-Flow, the PB Ratio measures the valuation of the stock relative to the underlying asset of the company.

The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.


Be Aware

Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.


Polaryx Therapeutics PB Ratio Related Terms


Polaryx Therapeutics PB Ratio Historical Data

* Premium members only.

The historical data trend for Polaryx Therapeutics's PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Polaryx Therapeutics PB Ratio Chart

Polaryx Therapeutics Annual Data
Trend Dec23 Dec24 Dec25
PB Ratio
0.00 0.00 0.00

Polaryx Therapeutics Quarterly Data
Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 142.64

PLYX vs GUTS, NTHI, PEPG: PB Ratio Comparison

For the Biotechnology subindustry, Polaryx Therapeutics's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Polaryx Therapeutics PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Polaryx Therapeutics's PB Ratio distribution charts can be found below:

* The bar in red indicates where Polaryx Therapeutics's PB Ratio falls into.


PLYX
13GF Score
Polaryx Therapeutics Inc PLYX
PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Polaryx Therapeutics PB Ratio Calculation

The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.

Polaryx Therapeutics's PB Ratio for today is calculated as follows:

PB Ratio=Share Price/Book Value per Share (Q: Mar. 2026)
=2.26/0.053
=42.64

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

It can also be calculated from the numbers for the whole company:

A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.

Frequently Asked Questions Learn more about PB Ratio →
What does a PB Ratio of 42.64 mean?
Polaryx Therapeutics (PLYX) has a PB Ratio of 42.64 as of Jul. 15, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Polaryx Therapeutics and its competitors. According to the industry distribution chart, Polaryx Therapeutics ranks #1194 out of 1228 companies in the Biotechnology industry, placing it in the top 97.2%.
Is Polaryx Therapeutics' PB Ratio too high?
Polaryx Therapeutics' current PB Ratio is 42.64. The Biotechnology industry median PB Ratio is 2.90. Polaryx Therapeutics' value of 42.64 is 1372.9% above this industry median. Based on the distribution chart, Polaryx Therapeutics ranks #1194 out of 1228 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Polaryx Therapeutics has a GF Score™ of 13/100, reflecting its overall financial health beyond just this single metric.
How does Polaryx Therapeutics' PB Ratio compare to GUTS and NTHI?
According to the Biotechnology industry distribution chart, Polaryx Therapeutics ranks #1194 out of 1228 companies for PB Ratio. This places Polaryx Therapeutics in the lower half of its industry. The industry median PB Ratio is 2.90. Polaryx Therapeutics' value of 42.64 is 1372.9% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.90, based on 1,228 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Polaryx Therapeutics's current PB Ratio of 42.64 is 1372.9% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Polaryx Therapeutics and its competitors. For the Biotechnology industry, the median PB Ratio is 2.90 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Polaryx Therapeutics's current PB Ratio is 42.64. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Polaryx Therapeutics stock overvalued right now?
Polaryx Therapeutics (PLYX) has a current PB Ratio of 42.64. The current PB Ratio is 42.64 and 1372.9% above the Biotechnology industry median of 2.90. Polaryx Therapeutics' overall GF Score™ is 13/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Polaryx Therapeutics (PLYX), the current PB Ratio is 42.64 as of Jul. 15, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Polaryx Therapeutics Business Description

Address South Tower, 140 East Ridgewood Avenue, Suite 415, Paramus, NJ, USA, 07652
Polaryx Therapeutics Inc is a clinical-stage biotechnology company committed to the discovery, development, and commercialization of novel, disease-modifying therapies for rare, pediatric LSDs. Its therapeutic approach focuses on treating the underlying pathophysiology of these diseases and addressing unmet needs. The company's therapeutic pipeline includes PLX-200, PLX-300, and PLX-100, which are orally available small-molecule drug candidates designed to address core pathological mechanisms common to LSDs. The Company has one reportable segment: lysosomal storage disorders. The lysosomal storage disorders segment consists of the Company's costs associated with the preclinical and clinical development of the Company's product candidates.
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$2.26
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