CBIO (Crescent Biopharma) Pretax Margin %: -2,240.90% (As of Mar. 2026)


CBIO Crescent Biopharma Inc CBIO
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What is Crescent Biopharma Pretax Margin %?

Crescent Biopharma CBIO -5.11% 10 Pretax Margin % is -2,240.90% as of Mar. 2026. GuruFocus rates CBIO with a GF Score™ of 10/100. The stock has 2 warning signs investors should review. Among 942 Biotechnology companies, Crescent Biopharma ranks worse than 80.89% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Crescent Biopharma's Pre-Tax Income for the three months ended in Mar. 2026 was $-23.28 Mil. Crescent Biopharma's Revenue for the three months ended in Mar. 2026 was $1.04 Mil. Therefore, Crescent Biopharma's pretax margin for the quarter that ended in Mar. 2026 was -2,240.90%.

The historical rank and industry rank for Crescent Biopharma's Pretax Margin % or its related term are showing as below:

CBIO' s Pretax Margin % Range Over the Past 10 Years
Min: -1401.16   Med: -1401.16   Max: -1347.11
Current: -1347.11


CBIO's Pretax Margin % is ranked worse than
80.89% of 942 companies
in the Biotechnology industry
Industry Median: -90.5 vs CBIO: -1347.11

Crescent Biopharma  (NAS:CBIO) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Crescent Biopharma Pretax Margin % Related Terms


Crescent Biopharma Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Crescent Biopharma's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Crescent Biopharma Pretax Margin % Chart

Crescent Biopharma Annual Data
Trend Dec24 Dec25
Pretax Margin %
0.00 -1,401.16

Crescent Biopharma Quarterly Data
Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial 0.00 0.00 0.00 -833.61 -2,240.90

CBIO vs KYTX, ZURA, ARVN: Pretax Margin % Comparison

For the Biotechnology subindustry, Crescent Biopharma's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Crescent Biopharma Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Crescent Biopharma's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Crescent Biopharma's Pretax Margin % falls into.


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Crescent Biopharma Inc CBIO
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Crescent Biopharma Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Crescent Biopharma's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-151.942/10.844
=-1,401.16 %

Crescent Biopharma's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-23.283/1.039
=-2,240.90 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -2,240.90% mean?
Crescent Biopharma (CBIO) has a Pretax Margin % of -2,240.90% as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Crescent Biopharma and its competitors. According to the industry distribution chart, Crescent Biopharma ranks #762 out of 942 companies in the Biotechnology industry, placing it in the top 80.9%.
Is Crescent Biopharma's Pretax Margin % too high?
Crescent Biopharma's current Pretax Margin % is -2,240.90%. Based on the distribution chart, Crescent Biopharma ranks #762 out of 942 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Crescent Biopharma has a GF Score™ of 10/100, reflecting its overall financial health beyond just this single metric.
How does Crescent Biopharma's Pretax Margin % compare to KYTX and ZURA?
According to the Biotechnology industry distribution chart, Crescent Biopharma ranks #762 out of 942 companies for Pretax Margin %. This places Crescent Biopharma in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Crescent Biopharma and its competitors. Crescent Biopharma's current Pretax Margin % is -2,240.90%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Crescent Biopharma stock overvalued right now?
Crescent Biopharma (CBIO) has a current Pretax Margin % of -2,240.90%. The current Pretax Margin % is -2,240.90%. Crescent Biopharma's overall GF Score™ is 10/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Crescent Biopharma (CBIO), the current Pretax Margin % is -2,240.90% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Crescent Biopharma Business Description

Other Exchanges C68:Germany
Address 300 Fifth Avenue, Waltham, MA, USA, 02451
Crescent Biopharma Inc is a biopharmaceutical company developing novel therapeutics to treat solid tumors, led by CR-001, a proprietary anti-PD-1/anti-VEGF bispecific antibody. Crescent's pipeline product CR-001 has the potential to deliver improved clinical efficacy and safety over pembrolizumab. CR-001 is a new molecular entity designed to replicate the functional properties of ivonescimab, a cooperative bispecific anti-PD-1/anti-VEGF antibody in development by Akeso Biopharma and Summit Therapeutics that delivered improved efficacy in a head-to-head Phase 3 clinical trial versus Keytruda in non-small cell lung cancer. The company focuses on advancing its second and third programs, CR-002 and CR-003, which are antibody drug conjugates (ADCs) against validated oncology targets.
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