CYCN (Cyclerion Therapeutics) Pretax Margin %: % (As of Mar. 2026)

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CYCN Cyclerion Therapeutics Inc CYCN
34 GF Score
Price $3.50
! 4 Warning Signs
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What is Cyclerion Therapeutics Pretax Margin %?

Cyclerion Therapeutics CYCN -4.16% 34 Pretax Margin % is % as of Mar. 2026. GuruFocus rates CYCN with a GF Score™ of 34/100. The stock has 4 warning signs investors should review. Among 942 Biotechnology companies, Cyclerion Therapeutics ranks worse than 63.06% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Cyclerion Therapeutics's Pre-Tax Income for the three months ended in Mar. 2026 was $-3.18 Mil. Cyclerion Therapeutics's Revenue for the three months ended in Mar. 2026 was $0.00 Mil. Therefore, Cyclerion Therapeutics's pretax margin for the quarter that ended in Mar. 2026 was %.

The historical rank and industry rank for Cyclerion Therapeutics's Pretax Margin % or its related term are showing as below:

CYCN' s Pretax Margin % Range Over the Past 10 Years
Min: -6143.43   Med: -2142.45   Max: -152.85
Current: -264.73


CYCN's Pretax Margin % is ranked worse than
63.06% of 942 companies
in the Biotechnology industry
Industry Median: -89.895 vs CYCN: -264.73

Cyclerion Therapeutics  (NAS:CYCN) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Cyclerion Therapeutics Pretax Margin % Related Terms


Cyclerion Therapeutics Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Cyclerion Therapeutics's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cyclerion Therapeutics Pretax Margin % Chart

Cyclerion Therapeutics Annual Data
Trend Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pretax Margin %
Get a 7-Day Free Trial Premium Member Only -1,555.63 -6,143.43 0.00 -152.85 -170.11

Cyclerion Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1,764.20 -348.39 -111.54 -77.95 0.00

CYCN vs BIVI, LNAI, CTXR: Pretax Margin % Comparison

For the Biotechnology subindustry, Cyclerion Therapeutics's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cyclerion Therapeutics Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cyclerion Therapeutics's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Cyclerion Therapeutics's Pretax Margin % falls into.


CYCN
34GF Score
Cyclerion Therapeutics Inc CYCN
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Cyclerion Therapeutics Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Cyclerion Therapeutics's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-3.528/2.074
=-170.11 %

Cyclerion Therapeutics's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-3.177/0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of % mean?
Cyclerion Therapeutics (CYCN) has a Pretax Margin % of % as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Cyclerion Therapeutics and its competitors. According to the industry distribution chart, Cyclerion Therapeutics ranks #594 out of 942 companies in the Biotechnology industry, placing it in the top 63.1%.
Is Cyclerion Therapeutics' Pretax Margin % too high?
Cyclerion Therapeutics' current Pretax Margin % is %. Based on the distribution chart, Cyclerion Therapeutics ranks #594 out of 942 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Cyclerion Therapeutics has a GF Score™ of 34/100, reflecting its overall financial health beyond just this single metric.
How does Cyclerion Therapeutics' Pretax Margin % compare to BIVI and LNAI?
According to the Biotechnology industry distribution chart, Cyclerion Therapeutics ranks #594 out of 942 companies for Pretax Margin %. This places Cyclerion Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Cyclerion Therapeutics and its competitors. Cyclerion Therapeutics's current Pretax Margin % is %. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cyclerion Therapeutics stock overvalued right now?
Cyclerion Therapeutics (CYCN) has a current Pretax Margin % of %. The current Pretax Margin % is %. Cyclerion Therapeutics' overall GF Score™ is 34/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Cyclerion Therapeutics (CYCN), the current Pretax Margin % is % as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Cyclerion Therapeutics Business Description

Address 245 First Street, 18th Floor, Cambridge, MA, USA, 02142
Cyclerion Therapeutics Inc is a clinical-stage biopharmaceutical company harnessing the power of soluble guanylate cyclase (sGC) pharmacology to discover, develop, and commercialize breakthrough treatments for serious and orphan diseases. The company focuses on enabling the full therapeutic potential of next-generation sGC stimulators and neuropsychiatric diseases. Its pipeline products include Olinciguat, Praliciguat, and others.
34GF Score

Get the complete analysis for CYCN

Pretax Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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