Axsome Therapeutics (MEX:AZSM) Pretax Margin %: -33.76% (As of Mar. 2026)

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MEX:AZSM Axsome Therapeutics Inc MEX:AZSM
52 GF Score
Price MXN1,519.00
GF Value MXN1,494.25
! 1 Warning Sign
View Full Analysis

What is Axsome Therapeutics Pretax Margin %?

Axsome Therapeutics MEX:AZSM 52 Pretax Margin % is -33.76% as of Mar. 2026. GuruFocus rates MEX:AZSM with a GF Score™ of 52/100 and a GF Value™ of MXN1,494.25. The stock has 1 warning sign investors should review. Among 941 Biotechnology companies, Axsome Therapeutics ranks better than 61.42% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Axsome Therapeutics's Pre-Tax Income for the three months ended in Mar. 2026 was MXN-1,164 Mil. Axsome Therapeutics's Revenue for the three months ended in Mar. 2026 was MXN3,448 Mil. Therefore, Axsome Therapeutics's pretax margin for the quarter that ended in Mar. 2026 was -33.76%.

The historical rank and industry rank for Axsome Therapeutics's Pretax Margin % or its related term are showing as below:

MEX:AZSM' s Pretax Margin % Range Over the Past 10 Years
Min: -373.99   Med: -81.26   Max: -26.66
Current: -26.66


MEX:AZSM's Pretax Margin % is ranked better than
61.42% of 941 companies
in the Biotechnology industry
Industry Median: -89.42 vs MEX:AZSM: -26.66

Axsome Therapeutics  (MEX:AZSM) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Axsome Therapeutics Pretax Margin % Related Terms


Axsome Therapeutics Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Axsome Therapeutics's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Axsome Therapeutics Pretax Margin % Chart

Axsome Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pretax Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -373.99 -88.06 -74.45 -28.77

Axsome Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -48.91 -32.61 -27.62 -14.35 -33.76

MEX:AZSM vs MDGL, IONS, BMRN: Pretax Margin % Comparison

For the Biotechnology subindustry, Axsome Therapeutics's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Axsome Therapeutics Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Axsome Therapeutics's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Axsome Therapeutics's Pretax Margin % falls into.


MEX:AZSM
52GF Score
Axsome Therapeutics Inc MEX:AZSM
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Axsome Therapeutics Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Axsome Therapeutics's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-3307.719/11496.567
=-28.77 %

Axsome Therapeutics's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-1163.867/3447.906
=-33.76 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -33.76% mean?
Axsome Therapeutics (MEX:AZSM) has a Pretax Margin % of -33.76% as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Axsome Therapeutics and its competitors. According to the industry distribution chart, Axsome Therapeutics ranks #363 out of 941 companies in the Biotechnology industry, placing it in the top 38.6%.
Is Axsome Therapeutics' Pretax Margin % too high?
Axsome Therapeutics' current Pretax Margin % is -33.76%. Based on the distribution chart, Axsome Therapeutics ranks #363 out of 941 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Axsome Therapeutics has a GF Score™ of 52/100, reflecting its overall financial health beyond just this single metric.
How does Axsome Therapeutics' Pretax Margin % compare to MDGL and IONS?
According to the Biotechnology industry distribution chart, Axsome Therapeutics ranks #363 out of 941 companies for Pretax Margin %. This puts Axsome Therapeutics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Axsome Therapeutics and its competitors. Axsome Therapeutics's current Pretax Margin % is -33.76%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Axsome Therapeutics stock overvalued right now?
Axsome Therapeutics (MEX:AZSM) has a current Pretax Margin % of -33.76%. The stock's GF Value™ is MXN1,494.25, compared to a current price of MXN1,519.00 — trading 1.7% above its estimated fair value. The current Pretax Margin % is -33.76%. Axsome Therapeutics' overall GF Score™ is 52/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Axsome Therapeutics (MEX:AZSM), the current Pretax Margin % is -33.76% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Axsome Therapeutics (MEX:AZSM) Overvalued in 2026?

Based on GuruFocus' analysis, Axsome Therapeutics stock appears to be overvalued. The current stock price of MXN1,519.00 is trading 1.7% above its estimated GF Value™ of MXN1,494.25.

Key valuation signals for MEX:AZSM:

  • Pretax Margin %: -33.76%
  • GF Value™: MXN1,494.25 vs. price of MXN1,519.00 (1.7% above fair value)
  • GF Score™: 52/100 with 1 warning sign

No single metric tells the full story. See the MEX:AZSM stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Axsome Therapeutics Business Description

Address One World Trade Center, 29th Floor, New York, NY, USA, 10007
Axsome Therapeutics Inc is a clinical-stage biopharmaceutical company. It is engaged in developing novel therapies for the management of the central nervous system, or CNS, disorders for which there are limited treatment options. Its pipeline products include AXS-05, AXS-07, AXS-12, and AXS-14. It manages its business as one operating segment and reporting unit, which is the business of developing and delivering novel therapies for the management of CNS disorders.
52GF Score

Get the complete analysis for MEX:AZSM

Pretax Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,519.00
Price
MXN1,494.25
GF Value