PureTech Health (CHIX:PRTCL) Profitability Rank: 2 (As of Dec. 2025) — Near Median

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CHIX:PRTCL PureTech Health PLC CHIX:PRTCL
65 GF Score
Price £1.22
GF Value £5.38
Valuation Possible Value Trap
! 3 Warning Signs
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What is PureTech Health Profitability Rank?

PureTech Health CHIX:PRTCL -0.57% 65 Profitability Rank is 2 as of Dec. 2025, which is at its 10-year median of 2.00. GuruFocus rates CHIX:PRTCL with a GF Score™ of 65/100 and a GF Value™ of £5.38 (Possible Value Trap). The stock has 3 warning signs investors should review.

PureTech Health has the Profitability Rank of 2. It has had trouble to make a profit.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

PureTech Health's Operating Margin % for the quarter that ended in Dec. 2025 was -1,801.38%. As of today, PureTech Health's Piotroski F-Score is 4.


PureTech Health Profitability Rank Related Terms


CHIX:PRTCL vs VRTX, REGN, RVMD: Profitability Rank Comparison

For the Biotechnology subindustry, PureTech Health's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


PureTech Health Profitability Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, PureTech Health's Profitability Rank distribution charts can be found below:

* The bar in red indicates where PureTech Health's Profitability Rank falls into.


CHIX:PRTCL
65GF Score
PureTech Health PLC CHIX:PRTCL
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

PureTech Health Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

PureTech Health has the Profitability Rank of 2. It has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

PureTech Health's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as:

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-37.793 / 2.098
=-1,801.38 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

PureTech Health has an F-score of 4 indicating the company's financial situation is typical for a stable company.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

Warning Sign:

PureTech Health PLC operating margin has been in a 5-year decline. The average rate of decline per year is -15%.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 2 mean?
PureTech Health (CHIX:PRTCL) has a Profitability Rank of 2 as of Dec. 2025. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on PureTech Health and its competitors. This is near median its historical median of 2.00. Over the past decade, PureTech Health's Profitability Rank has ranged from 1.00 to 3.00.
Is PureTech Health's Profitability Rank too high?
PureTech Health's current Profitability Rank of 2 is near median its 10-year median of 2.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 3.00. Overall, PureTech Health has a GF Score™ of 65/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does PureTech Health's Profitability Rank compare to VRTX and REGN?
PureTech Health's Profitability Rank of 2 can be compared against companies in the Biotechnology industry. Historically, PureTech Health's own Profitability Rank has ranged from 1.00 to 3.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Biotechnology company?
A good Profitability Rank depends on the Biotechnology industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on PureTech Health and its competitors. PureTech Health's current Profitability Rank is 2, which is near median its own 10-year median of 2.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PureTech Health stock overvalued right now?
Based on GuruFocus' analysis, PureTech Health (CHIX:PRTCL) is currently considered Possible Value Trap. The stock's GF Value™ is £5.38, compared to a current price of £1.22 — trading 77.2% below its estimated fair value. The current Profitability Rank is 2, which is near median its 10-year median of 2.00. PureTech Health's overall GF Score™ is 65/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For PureTech Health (CHIX:PRTCL), the current Profitability Rank is 2 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is PureTech Health (CHIX:PRTCL) Overvalued in 2026?

Based on GuruFocus' analysis, PureTech Health stock appears to be undervalued. The current stock price of £1.22 is trading 77.2% below its estimated GF Value™ of £5.38. GuruFocus considers PureTech Health to be Possible Value Trap.

Key valuation signals for CHIX:PRTCL:

  • Profitability Rank: 2 (near median its 10-year median of 2.00)
  • GF Value™: £5.38 vs. price of £1.22 (77.2% below fair value)
  • GF Score™: 65/100 with 3 warning signs

No single metric tells the full story. See the CHIX:PRTCL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


PureTech Health Business Description

Address 6 Tide Street, Suite 400, Boston, MA, USA, 02210
PureTech Health PLC, together with its subsidiaries, is a clinical-stage biopharma company developing medicines to modulate the adaptive human system. The company is focused on developing and commercializing differentiated medicines for devastating diseases, including inflammatory, immunological conditions, intractable cancers, lymphatic & gastrointestinal diseases, and neurological and neuropsychological disorders, among others. Its drug development pipeline consists of Deupirfenidone (LYT-100), for the potential treatment of idiopathic pulmonary fibrosis (IPF), LYT-200, SPT-300, an oral drug for depressive disorder, SPT-320, and others. The company's operating segments include Parent Companies & Other, which derives key revenue, Wholly-Owned Programs, and Controlled Founded Entities.
65GF Score

Get the complete analysis for CHIX:PRTCL

Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

£1.22
Price
£5.38
GF Value