DTIL (Precision BioSciences) Profitability Rank: 2 (As of Mar. 2026) — 100% Above Median

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DTIL Precision BioSciences Inc DTIL
50 GF Score
Price $7.17
GF Value $1.81
Valuation Significantly Overvalued
! 4 Warning Signs
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What is Precision BioSciences Profitability Rank?

Precision BioSciences DTIL -0.97% 50 Profitability Rank is 2 as of Mar. 2026, which is 100% above its 10-year median of 1.00. GuruFocus rates DTIL with a GF Score™ of 50/100 and a GF Value™ of $1.81 (Significantly Overvalued). The stock has 4 warning signs investors should review.

Precision BioSciences has the Profitability Rank of 2. It has had trouble to make a profit.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Precision BioSciences's Operating Margin % for the quarter that ended in Mar. 2026 was -83.73%. As of today, Precision BioSciences's Piotroski F-Score is 3.


Precision BioSciences Profitability Rank Related Terms


DTIL vs NERV, VYGR, GLSI: Profitability Rank Comparison

For the Biotechnology subindustry, Precision BioSciences's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Precision BioSciences Profitability Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Precision BioSciences's Profitability Rank distribution charts can be found below:

* The bar in red indicates where Precision BioSciences's Profitability Rank falls into.


DTIL
50GF Score
Precision BioSciences Inc DTIL
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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Precision BioSciences Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Precision BioSciences has the Profitability Rank of 2. It has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Precision BioSciences's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as:

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-9.075 / 10.838
=-83.73 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

Warning Sign:

Piotroski F-Score of 3 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

Precision BioSciences has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

Good Sign:

Precision BioSciences Inc operating margin is expanding. Margin expansion is usually a good sign.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 2 mean?
Precision BioSciences (DTIL) has a Profitability Rank of 2 as of Mar. 2026. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Precision BioSciences and its competitors. This is 100% above median its historical median of 1.00. Over the past decade, Precision BioSciences' Profitability Rank has ranged from 1.00 to 3.00.
Is Precision BioSciences' Profitability Rank too high?
Precision BioSciences' current Profitability Rank of 2 is 100% above median its 10-year median of 1.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 3.00. Overall, Precision BioSciences has a GF Score™ of 50/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Precision BioSciences' Profitability Rank compare to NERV and VYGR?
Precision BioSciences' Profitability Rank of 2 can be compared against companies in the Biotechnology industry. Historically, Precision BioSciences' own Profitability Rank has ranged from 1.00 to 3.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Biotechnology company?
A good Profitability Rank depends on the Biotechnology industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Precision BioSciences and its competitors. Precision BioSciences's current Profitability Rank is 2, which is 100% above median its own 10-year median of 1.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Precision BioSciences stock overvalued right now?
Based on GuruFocus' analysis, Precision BioSciences (DTIL) is currently considered Significantly Overvalued. The stock's GF Value™ is $1.81, compared to a current price of $7.17 — trading 296.1% above its estimated fair value. The current Profitability Rank is 2, which is 100% above median its 10-year median of 1.00. Precision BioSciences' overall GF Score™ is 50/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For Precision BioSciences (DTIL), the current Profitability Rank is 2 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Precision BioSciences (DTIL) Overvalued in 2026?

Based on GuruFocus' analysis, Precision BioSciences stock appears to be overvalued. The current stock price of $7.17 is trading 296.1% above its estimated GF Value™ of $1.81. GuruFocus considers Precision BioSciences to be Significantly Overvalued.

Key valuation signals for DTIL:

  • Profitability Rank: 2 (100% above median its 10-year median of 1.00)
  • GF Value™: $1.81 vs. price of $7.17 (296.1% above fair value)
  • GF Score™: 50/100 with 4 warning signs

No single metric tells the full story. See the DTIL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Precision BioSciences Business Description

Other Exchanges PBS0:Germany
Address 302 East Pettigrew Street, Dibrell Building, Suite A-100, Durham, NC, USA, 27701
Precision BioSciences Inc clinical stage gene editing company utilizing its proprietary ARCUS platform to concurrently develop two clinical-stage in vivo gene editing therapies. The ARCUS platform is used to develop in vivo gene editing therapies for sophisticated gene edits, including gene insertion (inserting DNA into gene to cause expression/add function), elimination (removing a genome, e.g. viral DNA), and excision (removing a large portion of a defective gene by delivering two ARCUS nucleases in a single adeno-associated virus ("AAV")).
50GF Score

Get the complete analysis for DTIL

Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$7.17
Price
$1.81
GF Value