Gilead Sciences (FRA:GIS) Profitability Rank: 8 (As of Jun. 2026) — Near Median

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FRA:GIS Gilead Sciences Inc FRA:GIS
74 GF Score
Price €125.66
GF Value €92.80
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Gilead Sciences Profitability Rank?

Gilead Sciences FRA:GIS -3.25% 74 Profitability Rank is 8 as of Jun. 2026, which is at its 10-year median of 8.00. GuruFocus rates FRA:GIS with a GF Score™ of 74/100 and a GF Value™ of €92.80 (Significantly Overvalued). The stock has 6 warning signs investors should review.

Gilead Sciences has the Profitability Rank of 8. It has a higher profitability and may stay that way.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Gilead Sciences's Operating Margin % for the quarter that ended in Jun. 2026 was 32.54%. As of today, Gilead Sciences's Piotroski F-Score is 5.


Gilead Sciences Profitability Rank Related Terms


FRA:GIS vs PFE, BMY, AMGN: Profitability Rank Comparison

For the Drug Manufacturers - General subindustry, Gilead Sciences's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Gilead Sciences Profitability Rank vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Gilead Sciences's Profitability Rank distribution charts can be found below:

* The bar in red indicates where Gilead Sciences's Profitability Rank falls into.


FRA:GIS
74GF Score
Gilead Sciences Inc FRA:GIS
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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Gilead Sciences Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Gilead Sciences has the Profitability Rank of 8. It has a higher profitability and may stay that way.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Gilead Sciences's Operating Margin % for the quarter that ended in Jun. 2026 is calculated as:

Operating Margin %=Operating Income (Q: Jun. 2026 ) / Revenue (Q: Jun. 2026 )
=2203.852 / 6773.004
=32.54 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

Gilead Sciences has an F-score of 5 indicating the company's financial situation is typical for a stable company.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

Warning Sign:

Gilead Sciences Inc operating margin has been in a 5-year decline. The average rate of decline per year is -1.4%.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 8 mean?
Gilead Sciences (FRA:GIS) has a Profitability Rank of 8 as of Jun. 2026. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Gilead Sciences and its competitors. This is near median its historical median of 8.00. Over the past decade, Gilead Sciences' Profitability Rank has ranged from 8.00 to 10.00.
Is Gilead Sciences' Profitability Rank too high?
Gilead Sciences' current Profitability Rank of 8 is near median its 10-year median of 8.00. Over the past 10 years, this metric has ranged from a low of 8.00 to a high of 10.00. Overall, Gilead Sciences has a GF Score™ of 74/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Gilead Sciences' Profitability Rank compare to PFE and BMY?
Gilead Sciences' Profitability Rank of 8 can be compared against companies in the Drug Manufacturers industry. Historically, Gilead Sciences' own Profitability Rank has ranged from 8.00 to 10.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Drug Manufacturers company?
A good Profitability Rank depends on the Drug Manufacturers industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Gilead Sciences and its competitors. Gilead Sciences's current Profitability Rank is 8, which is near median its own 10-year median of 8.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Gilead Sciences stock overvalued right now?
Based on GuruFocus' analysis, Gilead Sciences (FRA:GIS) is currently considered Significantly Overvalued. The stock's GF Value™ is €92.80, compared to a current price of €125.66 — trading 35.4% above its estimated fair value. The current Profitability Rank is 8, which is near median its 10-year median of 8.00. Gilead Sciences' overall GF Score™ is 74/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For Gilead Sciences (FRA:GIS), the current Profitability Rank is 8 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Gilead Sciences (FRA:GIS) Overvalued in 2026?

Based on GuruFocus' analysis, Gilead Sciences stock appears to be overvalued. The current stock price of €125.66 is trading 35.4% above its estimated GF Value™ of €92.80. GuruFocus considers Gilead Sciences to be Significantly Overvalued.

Key valuation signals for FRA:GIS:

  • Profitability Rank: 8 (near median its 10-year median of 8.00)
  • GF Value™: €92.80 vs. price of €125.66 (35.4% above fair value)
  • GF Score™: 74/100 with 6 warning signs

No single metric tells the full story. See the FRA:GIS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Gilead Sciences Business Description

Address 333 Lakeside Drive, Foster City, CA, USA, 94404
Gilead Sciences develops and markets therapies to treat and prevent life-threatening infectious diseases, with the core of its portfolio focused on HIV and hepatitis B and C. Gilead's acquisition of Pharmasset brought rights to hepatitis C drug Sovaldi, which is also part of newer combination regimens that remain standards of care. Gilead is also growing its presence in the oncology market via acquisitions, led by CAR-T cell therapy Yescarta/Tecartus (from Kite) and breast and bladder cancer therapy Trodelvy (from Immunomedics).
74GF Score

Get the complete analysis for FRA:GIS

Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€125.66
Price
€92.80
GF Value