Nektar Therapeutics (FRA:ITH0) Profitability Rank: 2 (As of Mar. 2026) — Near Median

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FRA:ITH0 Nektar Therapeutics FRA:ITH0
44 GF Score
Price €61.96
GF Value €4.78
Valuation Significantly Overvalued
! 5 Warning Signs
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What is Nektar Therapeutics Profitability Rank?

Nektar Therapeutics FRA:ITH0 +2.99% 44 Profitability Rank is 2 as of Mar. 2026, which is at its 10-year median of 2.00. GuruFocus rates FRA:ITH0 with a GF Score™ of 44/100 and a GF Value™ of €4.78 (Significantly Overvalued). The stock has 5 warning signs investors should review.

Nektar Therapeutics has the Profitability Rank of 2. It has had trouble to make a profit.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Nektar Therapeutics's Operating Margin % for the quarter that ended in Mar. 2026 was -352.24%. As of today, Nektar Therapeutics's Piotroski F-Score is 3.


Nektar Therapeutics Profitability Rank Related Terms


FRA:ITH0 vs PHVS, MLYS, NRIX: Profitability Rank Comparison

For the Biotechnology subindustry, Nektar Therapeutics's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Nektar Therapeutics Profitability Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Nektar Therapeutics's Profitability Rank distribution charts can be found below:

* The bar in red indicates where Nektar Therapeutics's Profitability Rank falls into.


FRA:ITH0
44GF Score
Nektar Therapeutics FRA:ITH0
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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Nektar Therapeutics Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Nektar Therapeutics has the Profitability Rank of 2. It has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Nektar Therapeutics's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as:

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-33.093 / 9.395
=-352.24 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

Warning Sign:

Piotroski F-Score of 3 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

Nektar Therapeutics has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

Good Sign:

Nektar Therapeutics operating margin is expanding. Margin expansion is usually a good sign.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 2 mean?
Nektar Therapeutics (FRA:ITH0) has a Profitability Rank of 2 as of Mar. 2026. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Nektar Therapeutics and its competitors. This is near median its historical median of 2.00. Over the past decade, Nektar Therapeutics' Profitability Rank has ranged from 1.00 to 4.00.
Is Nektar Therapeutics' Profitability Rank too high?
Nektar Therapeutics' current Profitability Rank of 2 is near median its 10-year median of 2.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 4.00. Overall, Nektar Therapeutics has a GF Score™ of 44/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Nektar Therapeutics' Profitability Rank compare to PHVS and MLYS?
Nektar Therapeutics' Profitability Rank of 2 can be compared against companies in the Biotechnology industry. Historically, Nektar Therapeutics' own Profitability Rank has ranged from 1.00 to 4.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Biotechnology company?
A good Profitability Rank depends on the Biotechnology industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Nektar Therapeutics and its competitors. Nektar Therapeutics's current Profitability Rank is 2, which is near median its own 10-year median of 2.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nektar Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Nektar Therapeutics (FRA:ITH0) is currently considered Significantly Overvalued. The stock's GF Value™ is €4.78, compared to a current price of €61.96 — trading 1196.2% above its estimated fair value. The current Profitability Rank is 2, which is near median its 10-year median of 2.00. Nektar Therapeutics' overall GF Score™ is 44/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For Nektar Therapeutics (FRA:ITH0), the current Profitability Rank is 2 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Nektar Therapeutics (FRA:ITH0) Overvalued in 2026?

Based on GuruFocus' analysis, Nektar Therapeutics stock appears to be overvalued. The current stock price of €61.96 is trading 1196.2% above its estimated GF Value™ of €4.78. GuruFocus considers Nektar Therapeutics to be Significantly Overvalued.

Key valuation signals for FRA:ITH0:

  • Profitability Rank: 2 (near median its 10-year median of 2.00)
  • GF Value™: €4.78 vs. price of €61.96 (1196.2% above fair value)
  • GF Score™: 44/100 with 5 warning signs

No single metric tells the full story. See the FRA:ITH0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Nektar Therapeutics Business Description

Other Exchanges NKTR:USA0UNL:UKITH0:Germany
Address 455 Mission Bay Boulevard South, San Francisco, CA, USA, 94158
Nektar Therapeutics is a clinical-stage, research-based biopharmaceutical company headquartered in San Francisco, California, and incorporated in Delaware, focused on discovering and developing medicines in the field of immunotherapy. The Company directs its efforts toward creating immunomodulatory agents that selectively induce, amplify, attenuate, or prevent immune responses to achieve desired therapeutic outcomes. Its pipeline of clinical-stage and preclinical-stage immunomodulatory agents targets the treatment of autoimmune diseases, including rezpegaldesleukin, NKTR-0165, NKTR-0166, and NKTR-422, as well as cancer, including NKTR-255.
44GF Score

Get the complete analysis for FRA:ITH0

Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€61.96
Price
€4.78
GF Value