INDP (Indaptus Therapeutics) Return-on-Tangible-Equity: -462.00% (As of Mar. 2026)


INDP Indaptus Therapeutics Inc INDP
26 GF Score
Price $3.00
! 1 Warning Sign
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What is Indaptus Therapeutics Return-on-Tangible-Equity?

Indaptus Therapeutics INDP -1.96% 26 Return-on-Tangible-Equity is -462.00% as of Mar. 2026. GuruFocus rates INDP with a GF Score™ of 26/100. The stock has 1 warning sign investors should review. Among 1,201 Biotechnology companies, Indaptus Therapeutics ranks worse than 97% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. Indaptus Therapeutics's annualized net income for the quarter that ended in Mar. 2026 was $-10.16 Mil. Indaptus Therapeutics's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $2.20 Mil. Therefore, Indaptus Therapeutics's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -462.00%.

The historical rank and industry rank for Indaptus Therapeutics's Return-on-Tangible-Equity or its related term are showing as below:

INDP' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -930.47   Med: -84.04   Max: -43.24
Current: -930.47

During the past 6 years, Indaptus Therapeutics's highest Return-on-Tangible-Equity was -43.24%. The lowest was -930.47%. And the median was -84.04%.

INDP's Return-on-Tangible-Equity is ranked worse than
97% of 1201 companies
in the Biotechnology industry
Industry Median: -42.4 vs INDP: -930.47

Indaptus Therapeutics  (NAS:INDP) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


Indaptus Therapeutics Return-on-Tangible-Equity Related Terms


Indaptus Therapeutics Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for Indaptus Therapeutics's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Indaptus Therapeutics Return-on-Tangible-Equity Chart

Indaptus Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial -43.24 -47.33 -84.04 -187.53 -587.54

Indaptus Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -537.52 -3,711.80 -811.46 -836.50 -462.00

INDP vs EDIT, ARTV, SGMT: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, Indaptus Therapeutics's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Indaptus Therapeutics Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Indaptus Therapeutics's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where Indaptus Therapeutics's Return-on-Tangible-Equity falls into.


INDP
26GF Score
Indaptus Therapeutics Inc INDP
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
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Indaptus Therapeutics Return-on-Tangible-Equity Calculation

Indaptus Therapeutics's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-20.849/( (3.945+3.152 )/ 2 )
=-20.849/3.5485
=-587.54 %

Indaptus Therapeutics's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-10.164/( (3.152+1.248)/ 2 )
=-10.164/2.2
=-462.00 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -462.00% mean?
Indaptus Therapeutics (INDP) has a Return-on-Tangible-Equity of -462.00% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Indaptus Therapeutics and its competitors. According to the industry distribution chart, Indaptus Therapeutics ranks #1165 out of 1201 companies in the Biotechnology industry, placing it in the top 97%.
Is Indaptus Therapeutics' Return-on-Tangible-Equity too high?
Indaptus Therapeutics' current Return-on-Tangible-Equity is -462.00%. Based on the distribution chart, Indaptus Therapeutics ranks #1165 out of 1201 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Indaptus Therapeutics has a GF Score™ of 26/100, reflecting its overall financial health beyond just this single metric.
How does Indaptus Therapeutics' Return-on-Tangible-Equity compare to EDIT and ARTV?
According to the Biotechnology industry distribution chart, Indaptus Therapeutics ranks #1165 out of 1201 companies for Return-on-Tangible-Equity. This places Indaptus Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Indaptus Therapeutics and its competitors. Indaptus Therapeutics's current Return-on-Tangible-Equity is -462.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Indaptus Therapeutics stock overvalued right now?
Indaptus Therapeutics (INDP) has a current Return-on-Tangible-Equity of -462.00%. The current Return-on-Tangible-Equity is -462.00%. Indaptus Therapeutics' overall GF Score™ is 26/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For Indaptus Therapeutics (INDP), the current Return-on-Tangible-Equity is -462.00% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Indaptus Therapeutics Business Description

Address 3 Columbus Circle 15th Floor, New York, NY, USA, 10019
Indaptus Therapeutics Inc is a clinical biotechnology company that has developed a novel and patented systemically-administered anti-cancer and anti-viral immunotherapy. Its approach is based on the hypothesis that efficient activation of both innate and adaptive immune cells and associated anti-tumor and anti-viral immune responses will require a multi-targeted package of immune system activating signals that can be administered safely intravenously. Its patented technology is composed of single strains of attenuated and killed, non-pathogenic, Gram-negative bacteria, designed to have reduced i.v. toxicity, but largely uncompromised ability to prime or activate many of the cellular components of innate and adaptive immunity. Its candidate, Decoy20 is for patients with solid tumors.
26GF Score

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