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Niki BioSolutionsNIKI +11.06%56 Return-on-Tangible-Equity is -5.38% as of Dec. 2025. GuruFocus rates NIKI with a GF Score™ of 56/100 and a GF Value™ of $11.69 (Modestly Undervalued). The stock has 1 warning sign investors should review. Among 1,199 Biotechnology companies, Niki BioSolutions ranks better than 74.56% on this metric.
Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. Niki BioSolutions's annualized net income for the quarter that ended in Dec. 2025 was $-1.23 Mil. Niki BioSolutions's average shareholder tangible equity for the quarter that ended in Dec. 2025 was $22.85 Mil. Therefore, Niki BioSolutions's annualized Return-on-Tangible-Equity for the quarter that ended in Dec. 2025 was -5.38%.
The historical rank and industry rank for Niki BioSolutions's Return-on-Tangible-Equity or its related term are showing as below:
NIKI'
s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -79.94 Med: -33.84 Max: 25.28
Current: -4.1
During the past 9 years, Niki BioSolutions's highest Return-on-Tangible-Equity was 25.28%. The lowest was -79.94%. And the median was -33.84%.
NIKI's Return-on-Tangible-Equity is ranked better than 74.56% of 1199
companies
in the Biotechnology industry
Industry Median: -42.4
vs NIKI: -4.10
Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.
Be Aware
Net Income is used.
Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.
Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.
Niki BioSolutions Return-on-Tangible-Equity Related Terms
Niki BioSolutions Return-on-Tangible-Equity Historical Data
* Premium members only.
The historical data trend for Niki BioSolutions's Return-on-Tangible-Equity can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
NIKI vs LABT, NCNA, SNGX: Return-on-Tangible-Equity Comparison
For the Biotechnology subindustry, Niki BioSolutions's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Niki BioSolutions Return-on-Tangible-Equity vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Niki BioSolutions's Return-on-Tangible-Equity distribution charts can be found below:
* The bar in red indicates where Niki BioSolutions's Return-on-Tangible-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data,
the net income data used here is four times the quarterly (Dec. 2025) net income data.
Return-on-Tangible-Equity is displayed in the 10-year financial page.
What does a Return-on-Tangible-Equity of -5.38% mean?
Niki BioSolutions (NIKI) has a Return-on-Tangible-Equity of -5.38% as of Dec. 2025. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Niki BioSolutions and its competitors. According to the industry distribution chart, Niki BioSolutions ranks #305 out of 1199 companies in the Biotechnology industry, placing it in the top 25.4%.
Is Niki BioSolutions' Return-on-Tangible-Equity too high?
Niki BioSolutions' current Return-on-Tangible-Equity is -5.38%. Based on the distribution chart, Niki BioSolutions ranks #305 out of 1199 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Niki BioSolutions has a GF Score™ of 56/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Niki BioSolutions' Return-on-Tangible-Equity compare to LABT and NCNA?
According to the Biotechnology industry distribution chart, Niki BioSolutions ranks #305 out of 1199 companies for Return-on-Tangible-Equity. This puts Niki BioSolutions in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Niki BioSolutions and its competitors. Niki BioSolutions's current Return-on-Tangible-Equity is -5.38%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Niki BioSolutions stock overvalued right now?
Based on GuruFocus' analysis, Niki BioSolutions (NIKI) is currently considered Modestly Undervalued. The stock's GF Value™ is $11.69, compared to a current price of $9.54 — trading 18.4% below its estimated fair value. The current Return-on-Tangible-Equity is -5.38%. Niki BioSolutions' overall GF Score™ is 56/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For Niki BioSolutions (NIKI), the current Return-on-Tangible-Equity is -5.38% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Niki BioSolutions (NIKI) Overvalued in 2026?
Based on GuruFocus' analysis, Niki BioSolutions stock appears to be undervalued.
The current stock price of $9.54 is trading 18.4% below its estimated GF Value™ of $11.69.
GuruFocus considers Niki BioSolutions to be Modestly Undervalued.
Key valuation signals for NIKI:
Return-on-Tangible-Equity: -5.38%
GF Value™: $11.69 vs. price of $9.54 (18.4% below fair value)
No single metric tells the full story. See the NIKI stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Aptorum Group Ltd is a clinical-stage biopharmaceutical company. It is engaged in the discovery, development, and commercialization of therapeutic assets to treat diseases with unmet medical needs, particularly in oncology (including orphan oncology indications) and infectious diseases. Aptorum's project pipeline includes SACT-1, a repurposed drug for the treatment of neuroblastoma, and ALS-4, a small molecule for the treatment of bacterial infections caused by Staphylococcus aureus, including but not limited to Methicillin-resistant Staphylococcus aureus (MRSA). Substantially all of the company's revenues are derived from within Hong Kong.
56GF Score
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