SLS (SELLAS Life Sciences Group) Return-on-Tangible-Equity: -38.55% (As of Mar. 2026)


SLS SELLAS Life Sciences Group Inc SLS
25 GF Score
Price $12.40
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What is SELLAS Life Sciences Group Return-on-Tangible-Equity?

SELLAS Life Sciences Group SLS +17.55% 25 Return-on-Tangible-Equity is -38.55% as of Mar. 2026. GuruFocus rates SLS with a GF Score™ of 25/100. The stock has 1 warning sign investors should review. Among 1,205 Biotechnology companies, SELLAS Life Sciences Group ranks worse than 56.85% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. SELLAS Life Sciences Group's annualized net income for the quarter that ended in Mar. 2026 was $-33.63 Mil. SELLAS Life Sciences Group's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $87.23 Mil. Therefore, SELLAS Life Sciences Group's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -38.55%.

The historical rank and industry rank for SELLAS Life Sciences Group's Return-on-Tangible-Equity or its related term are showing as below:

SLS' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -386.53   Med: -142.39   Max: -54.91
Current: -54.91

During the past 13 years, SELLAS Life Sciences Group's highest Return-on-Tangible-Equity was -54.91%. The lowest was -386.53%. And the median was -142.39%.

SLS's Return-on-Tangible-Equity is ranked worse than
56.85% of 1205 companies
in the Biotechnology industry
Industry Median: -42.47 vs SLS: -54.91

SELLAS Life Sciences Group  (NAS:SLS) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


SELLAS Life Sciences Group Return-on-Tangible-Equity Related Terms


SELLAS Life Sciences Group Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for SELLAS Life Sciences Group's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SELLAS Life Sciences Group Return-on-Tangible-Equity Chart

SELLAS Life Sciences Group Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial Premium Member Only Premium Member Only -106.75 -386.53 0.00 0.00 -70.22

SELLAS Life Sciences Group Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -139.25 -105.45 -79.95 -54.37 -38.55

SLS vs SNDX, CAPR, AGIO: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, SELLAS Life Sciences Group's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


SELLAS Life Sciences Group Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, SELLAS Life Sciences Group's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where SELLAS Life Sciences Group's Return-on-Tangible-Equity falls into.


SLS
25GF Score
SELLAS Life Sciences Group Inc SLS
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
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SELLAS Life Sciences Group Return-on-Tangible-Equity Calculation

SELLAS Life Sciences Group's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-26.863/( (7.551+68.957 )/ 2 )
=-26.863/38.254
=-70.22 %

SELLAS Life Sciences Group's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-33.628/( (68.957+105.498)/ 2 )
=-33.628/87.2275
=-38.55 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -38.55% mean?
SELLAS Life Sciences Group (SLS) has a Return-on-Tangible-Equity of -38.55% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on SELLAS Life Sciences Group and its competitors. According to the industry distribution chart, SELLAS Life Sciences Group ranks #685 out of 1205 companies in the Biotechnology industry, placing it in the top 56.8%.
Is SELLAS Life Sciences Group's Return-on-Tangible-Equity too high?
SELLAS Life Sciences Group's current Return-on-Tangible-Equity is -38.55%. Based on the distribution chart, SELLAS Life Sciences Group ranks #685 out of 1205 companies in the Biotechnology industry, which is below the industry midpoint. Overall, SELLAS Life Sciences Group has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does SELLAS Life Sciences Group's Return-on-Tangible-Equity compare to SNDX and CAPR?
According to the Biotechnology industry distribution chart, SELLAS Life Sciences Group ranks #685 out of 1205 companies for Return-on-Tangible-Equity. This places SELLAS Life Sciences Group in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on SELLAS Life Sciences Group and its competitors. SELLAS Life Sciences Group's current Return-on-Tangible-Equity is -38.55%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SELLAS Life Sciences Group stock overvalued right now?
SELLAS Life Sciences Group (SLS) has a current Return-on-Tangible-Equity of -38.55%. The current Return-on-Tangible-Equity is -38.55%. SELLAS Life Sciences Group's overall GF Score™ is 25/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For SELLAS Life Sciences Group (SLS), the current Return-on-Tangible-Equity is -38.55% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

SELLAS Life Sciences Group Business Description

Other Exchanges RXK3:Germany
Address 7 Times Square, Suite 2503, New York, NY, USA, 10036
SELLAS Life Sciences Group Inc is a late-stage clinical biopharmaceutical company focused on the development of novel therapeutics for a broad range of cancer indications. The company's product candidates currently include galinpepimut-S, or GPS, a peptide immunotherapy directed against the Wilms tumor 1, or WT1, antigen, and GFH009, a selective small molecule cyclin-dependent kinase 9, or CDK9, inhibitor.
25GF Score

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