ANL (Adlai Nortye) ROA %: -64.59% (As of Dec. 2025)


What is Adlai Nortye ROA %?

Adlai Nortye ANL -1.57% ROA % is -64.59% as of Dec. 2025. The stock has 7 warning signs investors should review. Among 1,422 Biotechnology companies, Adlai Nortye ranks worse than 69.06% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Adlai Nortye's annualized Net Income for the quarter that ended in Dec. 2025 was $-34.39 Mil. Adlai Nortye's average Total Assets over the quarter that ended in Dec. 2025 was $53.24 Mil. Therefore, Adlai Nortye's annualized ROA % for the quarter that ended in Dec. 2025 was -64.59%.

The historical rank and industry rank for Adlai Nortye's ROA % or its related term are showing as below:

ANL' s ROA % Range Over the Past 10 Years
Min: -107.73   Med: -57.56   Max: -43.04
Current: -59.96

During the past 5 years, Adlai Nortye's highest ROA % was -43.04%. The lowest was -107.73%. And the median was -57.56%.

ANL's ROA % is ranked worse than
69.06% of 1422 companies
in the Biotechnology industry
Industry Median: -32.87 vs ANL: -59.96

Adlai Nortye  (NAS:ANL) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Dec. 2025 )
=Net Income/Total Assets
=-34.386/53.239
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-34.386 / 10)*(10 / 53.239)
=Net Margin %*Asset Turnover
=-343.86 %*0.1878
=-64.59 %

Note: The Net Income data used here is two times the semi-annual (Dec. 2025) net income data. The Revenue data used here is two times the semi-annual (Dec. 2025) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Adlai Nortye ROA % Related Terms


Adlai Nortye ROA % Historical Data

* Premium members only.

The historical data trend for Adlai Nortye's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Adlai Nortye ROA % Chart

Adlai Nortye Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
-43.04 -57.56 -107.73 -51.49 -67.22

Adlai Nortye Semi-Annual Data
Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROA % Get a 7-Day Free Trial Premium Member Only -62.66 -46.43 -54.22 -51.17 -64.59

ANL vs PHAT, AURA, RLMD: ROA % Comparison

For the Biotechnology subindustry, Adlai Nortye's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Adlai Nortye ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Adlai Nortye's ROA % distribution charts can be found below:

* The bar in red indicates where Adlai Nortye's ROA % falls into.



Adlai Nortye ROA % Calculation

Adlai Nortye's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-35.528/( (71.27+34.433)/ 2 )
=-35.528/52.8515
=-67.22 %

Adlai Nortye's annualized ROA % for the quarter that ended in Dec. 2025 is calculated as:

ROA %=Net Income (Q: Dec. 2025 )/( (Total Assets (Q: Jun. 2025 )+Total Assets (Q: Dec. 2025 ))/ count )
=-34.386/( (72.045+34.433)/ 2 )
=-34.386/53.239
=-64.59 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is two times the semi-annual (Dec. 2025) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -64.59% mean?
Adlai Nortye (ANL) has a ROA % of -64.59% as of Dec. 2025. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Adlai Nortye and its competitors. According to the industry distribution chart, Adlai Nortye ranks #982 out of 1422 companies in the Biotechnology industry, placing it in the top 69.1%.
Is Adlai Nortye's ROA % too high?
Adlai Nortye's current ROA % is -64.59%. Based on the distribution chart, Adlai Nortye ranks #982 out of 1422 companies in the Biotechnology industry, which is below the industry midpoint.
How does Adlai Nortye's ROA % compare to PHAT and AURA?
According to the Biotechnology industry distribution chart, Adlai Nortye ranks #982 out of 1422 companies for ROA %. This places Adlai Nortye in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Adlai Nortye and its competitors. Adlai Nortye's current ROA % is -64.59%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Adlai Nortye stock overvalued right now?
Adlai Nortye (ANL) has a current ROA % of -64.59%. The current ROA % is -64.59%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Adlai Nortye (ANL), the current ROA % is -64.59% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Adlai Nortye Business Description

Other Exchanges N2U0:Germany
Address 685 US Highway 1, New Jersey Biotechnology Development Center, 2nd Floor, North Brunswick, NJ, USA, 08902
Adlai Nortye Ltd is a clinical-stage company at the forefront of discovering and developing cancer therapies. The company is building a robust pipeline of drug candidates focused on two key areas where it believes it can make a difference RAS-targeting therapies: its is tackling RAS-driven cancers with AN9025, an oral pan-RAS(ON) inhibitor, and AN4035, a CEACAM5-targeting ADC delivering a potent pan-RAS(ON) inhibitor directly to tumors; Next-generation cancer immunotherapies: its candidates, AN8025 (a tri-functional fusion protein of alphaPD-L1 x CD86 variant x LAG3 variant), a T-cell and antigen-presenting cell modulator, and AN4005 (a first-in-class oral small-molecule PD-L1 inhibitor), are designed to activate cancer immunity in novel ways.