KLTO (Klotho Neurosciences) ROA %: -110.75% (As of Sep. 2025)


KLTO Klotho Neurosciences Inc KLTO
22 GF Score
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What is Klotho Neurosciences ROA %?

Klotho Neurosciences KLTO 22 ROA % is -110.75% as of Sep. 2025. GuruFocus rates KLTO with a GF Score™ of 22/100. The stock has 1 warning sign investors should review.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Klotho Neurosciences's annualized Net Income for the quarter that ended in Sep. 2025 was $-11.58 Mil. Klotho Neurosciences's average Total Assets over the quarter that ended in Sep. 2025 was $10.46 Mil. Therefore, Klotho Neurosciences's annualized ROA % for the quarter that ended in Sep. 2025 was -110.75%.

The historical rank and industry rank for Klotho Neurosciences's ROA % or its related term are showing as below:

KLTO' s ROA % Range Over the Past 10 Years
Min: -264.52   Med: -69.94   Max: -29.88
Current: -195.82

During the past 4 years, Klotho Neurosciences's highest ROA % was -29.88%. The lowest was -264.52%. And the median was -69.94%.

KLTO's ROA % is not ranked
in the Biotechnology industry.
Industry Median: -32.9 vs KLTO: -195.82

Klotho Neurosciences  (NAS:KLTO) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Sep. 2025 )
=Net Income/Total Assets
=-11.584/10.4595
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-11.584 / 0)*(0 / 10.4595)
=Net Margin %*Asset Turnover
=N/A %*0
=-110.75 %

Note: The Net Income data used here is four times the quarterly (Sep. 2025) net income data. The Revenue data used here is four times the quarterly (Sep. 2025) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Klotho Neurosciences ROA % Related Terms


Klotho Neurosciences ROA % Historical Data

* Premium members only.

The historical data trend for Klotho Neurosciences's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Klotho Neurosciences ROA % Chart

Klotho Neurosciences Annual Data
Trend Dec21 Dec22 Dec23 Dec24
ROA %
-106.43 -33.45 -29.88 -264.52

Klotho Neurosciences Quarterly Data
Dec21 Jun22 Dec22 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -410.05 -336.03 -328.29 -236.71 -110.75

KLTO vs KTTA, JUNS, ZEOX: ROA % Comparison

For the Biotechnology subindustry, Klotho Neurosciences's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Klotho Neurosciences ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Klotho Neurosciences's ROA % distribution charts can be found below:

* The bar in red indicates where Klotho Neurosciences's ROA % falls into.


KLTO
22GF Score
Klotho Neurosciences Inc KLTO
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
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Klotho Neurosciences ROA % Calculation

Klotho Neurosciences's annualized ROA % for the fiscal year that ended in Dec. 2024 is calculated as:

ROA %=Net Income (A: Dec. 2024 )/( (Total Assets (A: Dec. 2023 )+Total Assets (A: Dec. 2024 ))/ count )
=-6.15/( (2.193+2.457)/ 2 )
=-6.15/2.325
=-264.52 %

Klotho Neurosciences's annualized ROA % for the quarter that ended in Sep. 2025 is calculated as:

ROA %=Net Income (Q: Sep. 2025 )/( (Total Assets (Q: Jun. 2025 )+Total Assets (Q: Sep. 2025 ))/ count )
=-11.584/( (10.846+10.073)/ 2 )
=-11.584/10.4595
=-110.75 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Sep. 2025) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -110.75% mean?
Klotho Neurosciences (KLTO) has a ROA % of -110.75% as of Sep. 2025. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Klotho Neurosciences and its competitors.
Is Klotho Neurosciences' ROA % too high?
Klotho Neurosciences' current ROA % is -110.75%. Overall, Klotho Neurosciences has a GF Score™ of 22/100, reflecting its overall financial health beyond just this single metric.
How does Klotho Neurosciences' ROA % compare to KTTA and JUNS?
Klotho Neurosciences' ROA % of -110.75% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Klotho Neurosciences and its competitors. Klotho Neurosciences's current ROA % is -110.75%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Klotho Neurosciences stock overvalued right now?
Klotho Neurosciences (KLTO) has a current ROA % of -110.75%. The current ROA % is -110.75%. Klotho Neurosciences' overall GF Score™ is 22/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Klotho Neurosciences (KLTO), the current ROA % is -110.75% as of Sep. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Klotho Neurosciences Business Description

Address 13576 Walnut Street, Suite A, Omaha, NE, USA, 68144
Klotho Neurosciences Inc is in the development of essential medicines for the treatment of chronic diseases: Cancer, Cardiovascular, and Neurodegenerative disorders. The Company currently has acquired two licensed platforms: a generic drug portfolio and a biosimilar biologics platform that uses biologic therapies to treat cancer, and a proprietary, patented gene therapy platform which uses a gene therapy approach to introduce a therapeutic protein called Klotho inside the body to treat neurodegenerative diseases. Company pipeline includes KLTO 101, KLTO 202, KLTO 301.
22GF Score

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