Oxford BioMedica (LSE:OXB) ROA %: -2.78% (As of Dec. 2025)


LSE:OXB Oxford BioMedica PLC LSE:OXB
68 GF Score
Price £6.33
GF Value £5.36
Valuation Modestly Overvalued
! 5 Warning Signs
View Full Analysis

What is Oxford BioMedica ROA %?

Oxford BioMedica LSE:OXB -0.16% 68 ROA % is -2.78% as of Dec. 2025. GuruFocus rates LSE:OXB with a GF Score™ of 68/100 and a GF Value™ of £5.36 (Modestly Overvalued). The stock has 5 warning signs investors should review. Among 1,422 Biotechnology companies, Oxford BioMedica ranks better than 67.93% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Oxford BioMedica's annualized Net Income for the quarter that ended in Dec. 2025 was £-7.5 Mil. Oxford BioMedica's average Total Assets over the quarter that ended in Dec. 2025 was £271.0 Mil. Therefore, Oxford BioMedica's annualized ROA % for the quarter that ended in Dec. 2025 was -2.78%.

The historical rank and industry rank for Oxford BioMedica's ROA % or its related term are showing as below:

LSE:OXB' s ROA % Range Over the Past 10 Years
Min: -44.21   Med: -12.44   Max: 9.03
Current: -11.68

During the past 13 years, Oxford BioMedica's highest ROA % was 9.03%. The lowest was -44.21%. And the median was -12.44%.

LSE:OXB's ROA % is ranked better than
67.93% of 1422 companies
in the Biotechnology industry
Industry Median: -32.87 vs LSE:OXB: -11.68

Oxford BioMedica  (LSE:OXB) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Dec. 2025 )
=Net Income/Total Assets
=-7.536/271.018
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-7.536 / 191.036)*(191.036 / 271.018)
=Net Margin %*Asset Turnover
=-3.94 %*0.7049
=-2.78 %

Note: The Net Income data used here is two times the semi-annual (Dec. 2025) net income data. The Revenue data used here is two times the semi-annual (Dec. 2025) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Oxford BioMedica ROA % Related Terms


Oxford BioMedica ROA % Historical Data

* Premium members only.

The historical data trend for Oxford BioMedica's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Oxford BioMedica ROA % Chart

Oxford BioMedica Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 9.03 -11.23 -44.21 -17.85 -10.81

Oxford BioMedica Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -67.05 -26.13 -8.98 -23.54 -2.78

LSE:OXB vs VRTX, REGN, ALNY: ROA % Comparison

For the Biotechnology subindustry, Oxford BioMedica's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Oxford BioMedica ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Oxford BioMedica's ROA % distribution charts can be found below:

* The bar in red indicates where Oxford BioMedica's ROA % falls into.


LSE:OXB
68GF Score
Oxford BioMedica PLC LSE:OXB
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Oxford BioMedica ROA % Calculation

Oxford BioMedica's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-30.128/( (231.643+325.719)/ 2 )
=-30.128/278.681
=-10.81 %

Oxford BioMedica's annualized ROA % for the quarter that ended in Dec. 2025 is calculated as:

ROA %=Net Income (Q: Dec. 2025 )/( (Total Assets (Q: Jun. 2025 )+Total Assets (Q: Dec. 2025 ))/ count )
=-7.536/( (216.317+325.719)/ 2 )
=-7.536/271.018
=-2.78 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is two times the semi-annual (Dec. 2025) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -2.78% mean?
Oxford BioMedica (LSE:OXB) has a ROA % of -2.78% as of Dec. 2025. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Oxford BioMedica and its competitors. According to the industry distribution chart, Oxford BioMedica ranks #456 out of 1422 companies in the Biotechnology industry, placing it in the top 32.1%.
Is Oxford BioMedica's ROA % too high?
Oxford BioMedica's current ROA % is -2.78%. Based on the distribution chart, Oxford BioMedica ranks #456 out of 1422 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Oxford BioMedica has a GF Score™ of 68/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Oxford BioMedica's ROA % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Oxford BioMedica ranks #456 out of 1422 companies for ROA %. This puts Oxford BioMedica in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Oxford BioMedica and its competitors. Oxford BioMedica's current ROA % is -2.78%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oxford BioMedica stock overvalued right now?
Based on GuruFocus' analysis, Oxford BioMedica (LSE:OXB) is currently considered Modestly Overvalued. The stock's GF Value™ is £5.36, compared to a current price of £6.33 — trading 18.1% above its estimated fair value. The current ROA % is -2.78%. Oxford BioMedica's overall GF Score™ is 68/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Oxford BioMedica (LSE:OXB), the current ROA % is -2.78% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Oxford BioMedica (LSE:OXB) Overvalued in 2026?

Based on GuruFocus' analysis, Oxford BioMedica stock appears to be overvalued. The current stock price of £6.33 is trading 18.1% above its estimated GF Value™ of £5.36. GuruFocus considers Oxford BioMedica to be Modestly Overvalued.

Key valuation signals for LSE:OXB:

  • ROA %: -2.78%
  • GF Value™: £5.36 vs. price of £6.33 (18.1% above fair value)
  • GF Score™: 68/100 with 5 warning signs

No single metric tells the full story. See the LSE:OXB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Oxford BioMedica Business Description

Other Exchanges OXBDF:USAOXBl:UKOXO:Germany
Address Transport Way, Windrush Court, Oxford, GBR, OX4 6LT
Oxford BioMedica PLC is a contract development and manufacturing organization (CDMO) focused on cell and gene therapy. The company specializes in viral vector development and manufacturing for cell and gene therapy, with expertise in lentivirus, adeno-associated virus (AAV), adenovirus, and other viral vector types. Geographically, it derives maximum revenue from the United States, and the rest from Europe, the UK, and the Rest of the world.
68GF Score

Get the complete analysis for LSE:OXB

ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

£6.33
Price
£5.36
GF Value