Tvardi Therapeutics (LTS:0HTC) ROC (Joel Greenblatt) %: -15,496.70% (As of Mar. 2026)

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LTS:0HTC Tvardi Therapeutics Inc LTS:0HTC
18 GF Score
Price $3.38
! 1 Warning Sign
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What is Tvardi Therapeutics ROC (Joel Greenblatt) %?

Tvardi Therapeutics LTS:0HTC 18 ROC (Joel Greenblatt) % is -15,496.70% as of Mar. 2026. GuruFocus rates LTS:0HTC with a GF Score™ of 18/100. The stock has 1 warning sign investors should review. Among 1,323 Biotechnology companies, Tvardi Therapeutics ranks worse than 67.27% on this metric.

Joel Greenblatt defined Return on Capital differently in his book The Little Book That Still Beats the Market (Little Books. Big Profits). He defines ROC (Joel Greenblatt) % as EBIT divided by the total of Property, Plant and Equipment and net working capital. Tvardi Therapeutics's annualized ROC (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -15,496.70%.

The historical rank and industry rank for Tvardi Therapeutics's ROC (Joel Greenblatt) % or its related term are showing as below:

LTS:0HTC' s ROC (Joel Greenblatt) % Range Over the Past 10 Years
Min: -10785.48   Med: -6088.06   Max: -1013.6
Current: -1013.6

During the past 4 years, Tvardi Therapeutics's highest ROC (Joel Greenblatt) % was -1013.60%. The lowest was -10785.48%. And the median was -6088.06%.

LTS:0HTC's ROC (Joel Greenblatt) % is ranked worse than
67.27% of 1323 companies
in the Biotechnology industry
Industry Median: -297.52 vs LTS:0HTC: -1013.60

Tvardi Therapeutics's 5-Year average Growth Rate of ROC (Joel Greenblatt) % was 0.00% per year.


Tvardi Therapeutics  (LTS:0HTC) ROC (Joel Greenblatt) % Explanation

The way Joel Greenblatt defines Return on Capital is a more accurate measure of how efficiently the company generates returns onthe capital actually invested in the business. EBIT is used instead of net income because the tax and interest payment may be affected by factors other than the core business operation. Intangible assets are not included in the calculation because they don't need to be replaced.

Joel Greenblatt uses his definition of Return on Capital and Earnings Yield (Joel Greenblatt) % to rank companies.


Tvardi Therapeutics ROC (Joel Greenblatt) % Related Terms


Tvardi Therapeutics ROC (Joel Greenblatt) % Historical Data

* Premium members only.

The historical data trend for Tvardi Therapeutics's ROC (Joel Greenblatt) % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tvardi Therapeutics ROC (Joel Greenblatt) % Chart

Tvardi Therapeutics Annual Data
Trend Dec22 Dec23 Dec24 Dec25
ROC (Joel Greenblatt) %
-4,465.00 -3,902.59 -7,711.11 -10,785.48

Tvardi Therapeutics Quarterly Data
Dec22 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROC (Joel Greenblatt) % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only -1,234.30 -509.05 -408.15 -14,485.92 -15,496.70

LTS:0HTC vs HOWL, TPST, XCUR: ROC (Joel Greenblatt) % Comparison

For the Biotechnology subindustry, Tvardi Therapeutics's ROC (Joel Greenblatt) %, along with its competitors' market caps and ROC (Joel Greenblatt) % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Tvardi Therapeutics ROC (Joel Greenblatt) % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Tvardi Therapeutics's ROC (Joel Greenblatt) % distribution charts can be found below:

* The bar in red indicates where Tvardi Therapeutics's ROC (Joel Greenblatt) % falls into.


LTS:0HTC
18GF Score
Tvardi Therapeutics Inc LTS:0HTC
ROC (Joel Greenblatt) % is just one metric. See GF Score™, valuation, warning signs, and more.
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Tvardi Therapeutics ROC (Joel Greenblatt) % Calculation

Joel Greenblatt defined Return on Capital differently in his book The Little Book That Still Beats the Market (Little Books. Big Profits) . He defines Return on Capital as follows:

ROC (Joel Greenblatt) %=EBIT/Average of (Net fixed Assets + Net Working Capital)

EBIT stands for Earnings Before Interest and Taxes.

Fixed Assets are also known as non-current assets. They include the Property, Plant and Equipment that the firm needs in its operation.

GuruFocus calculates net working capital as: (Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Deferred Revenue + Other Current Liabilities). We're trying to account for OPERATING assets and liabilities (part of daily business) when calculating working capital. Cash and marketable securities are considered NON-OPERATING assets and are not included in calculation. We will also back out all interest bearing debt, short term debt and the portion of long term debt that is due in the current period from the current liabilities. This debt will be considered when computing cost of capital and it would be inappropriate to count it twice.

Working Capital(Q: Dec. 2025 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(0 + 0 + 0.727) - (9.629 + 0 + 1.297)
=-10.199

Working Capital(Q: Mar. 2026 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(0 + 0 + 0.345) - (10.409 + 0 + 0.729)
=-10.793

When net working capital is negative, 0 is used.

So ROC (Joel Greenblatt) % of Tvardi Therapeutics for the quarter that ended in Mar. 2026 can be restated as:

ROC (Joel Greenblatt) %(Q: Mar. 2026 )
=EBIT/Average of (Net fixed Assets + Net Working Capital)
=EBIT/Average of (Property, Plant and Equipment+Net Working Capital)
     Q: Dec. 2025  Q: Mar. 2026
=EBIT/( ( (Property, Plant and Equipment + Net Working Capital) + (Property, Plant and Equipment + Net Working Capital) )/ count )
=-28.204/( ( (0.196 + max(-10.199, 0)) + (0.168 + max(-10.793, 0)) )/ 2 )
=-28.204/( ( 0.196 + 0.168 )/ 2 )
=-28.204/0.182
=-15,496.70 %

Note: The EBIT data used here is four times the quarterly (Mar. 2026) EBIT data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROC (Joel Greenblatt) % of -15,496.70% mean?
Tvardi Therapeutics (LTS:0HTC) has a ROC (Joel Greenblatt) % of -15,496.70% as of Mar. 2026. Joel Greenblatt's return on capital is the ratio of EBIT to average fixed assets and net working capital. View historical data on Tvardi Therapeutics and its competitors. According to the industry distribution chart, Tvardi Therapeutics ranks #890 out of 1323 companies in the Biotechnology industry, placing it in the top 67.3%.
Is Tvardi Therapeutics' ROC (Joel Greenblatt) % too high?
Tvardi Therapeutics' current ROC (Joel Greenblatt) % is -15,496.70%. Based on the distribution chart, Tvardi Therapeutics ranks #890 out of 1323 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Tvardi Therapeutics has a GF Score™ of 18/100, reflecting its overall financial health beyond just this single metric.
How does Tvardi Therapeutics' ROC (Joel Greenblatt) % compare to HOWL and TPST?
According to the Biotechnology industry distribution chart, Tvardi Therapeutics ranks #890 out of 1323 companies for ROC (Joel Greenblatt) %. This places Tvardi Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROC (Joel Greenblatt) % for a Biotechnology company?
A good ROC (Joel Greenblatt) % depends on the Biotechnology industry context. However, ROC (Joel Greenblatt) % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROC (Joel Greenblatt) % mean?
A high ROC (Joel Greenblatt) % can signal that a stock is expensive relative to its fundamentals. Joel Greenblatt's return on capital is the ratio of EBIT to average fixed assets and net working capital. View historical data on Tvardi Therapeutics and its competitors. Tvardi Therapeutics's current ROC (Joel Greenblatt) % is -15,496.70%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tvardi Therapeutics stock overvalued right now?
Tvardi Therapeutics (LTS:0HTC) has a current ROC (Joel Greenblatt) % of -15,496.70%. The current ROC (Joel Greenblatt) % is -15,496.70%. Tvardi Therapeutics' overall GF Score™ is 18/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROC (Joel Greenblatt) % calculated?
ROC (Joel Greenblatt) % is calculated from a company's financial statements. For Tvardi Therapeutics (LTS:0HTC), the current ROC (Joel Greenblatt) % is -15,496.70% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Tvardi Therapeutics Business Description

Other Exchanges TVRD:USA69C:Germany
Address 3 Sugar Creek Center boulevard, Suite 525, Sugar Land, TX, USA, 77478
Tvardi Therapeutics Inca clinical-stage biopharmaceutical company focused on the development of novel, oral, small molecule therapies targeting Signal Transducer and Activator of Transcription 3 (STAT3) to treat inflammatory and proliferative diseases with unmet need. Its pipeline includes two oral, small molecule STAT3 inhibitors: TTI-101 and TTI-109. TTI-101 is its first-generation direct STAT3 inhibitor, currently in Phase 1b/2 clinical development in hepatocellular carcinoma (HCC). TTI-109 is a phosphate prodrug of TTI-101 that is mechanistically identical to its parent molecule but is designed to enhance its ability to target STAT3.
18GF Score

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ROC (Joel Greenblatt) % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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