Inovio Pharmaceuticals (FRA:GBM) ROC %: -182.99% (As of Mar. 2026)

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FRA:GBM Inovio Pharmaceuticals Inc FRA:GBM
43 GF Score
Price €1.02
GF Value €0.19
Valuation Significantly Overvalued
! 4 Warning Signs
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What is Inovio Pharmaceuticals ROC %?

Inovio Pharmaceuticals FRA:GBM -3.24% 43 ROC % is -182.99% as of Mar. 2026. GuruFocus rates FRA:GBM with a GF Score™ of 43/100 and a GF Value™ of €0.19 (Significantly Overvalued). The stock has 4 warning signs investors should review.

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. Inovio Pharmaceuticals's annualized return on capital (ROC %) for the quarter that ended in Mar. 2026 was -182.99%.

As of today (2026-07-13), Inovio Pharmaceuticals's WACC % is 11.65%. Inovio Pharmaceuticals's ROC % is -170.97% (calculated using TTM income statement data). Inovio Pharmaceuticals earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Inovio Pharmaceuticals  (FRA:GBM) ROC % Explanation

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Inovio Pharmaceuticals's WACC % is 11.65%. Inovio Pharmaceuticals's ROC % is -170.97% (calculated using TTM income statement data). Inovio Pharmaceuticals earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Inovio Pharmaceuticals ROC % Related Terms


Inovio Pharmaceuticals ROC % Historical Data

* Premium members only.

The historical data trend for Inovio Pharmaceuticals's ROC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Inovio Pharmaceuticals ROC % Chart

Inovio Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -349.24 -454.91 -267.65 -260.73 -176.40

Inovio Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -262.73 -248.37 -147.46 -108.90 -182.99
FRA:GBM
43GF Score
Inovio Pharmaceuticals Inc FRA:GBM
ROC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Inovio Pharmaceuticals ROC % Calculation

Inovio Pharmaceuticals's annualized Return on Capital (ROC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-74.146 * ( 1 - 0% )/( (39.275 + 44.789)/ 2 )
=-74.146/42.032
=-176.40 %

where

Inovio Pharmaceuticals's annualized Return on Capital (ROC %) for the quarter that ended in Mar. 2026 is calculated as:

ROC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=-75.948 * ( 1 - 0% )/( (44.789 + 38.219)/ 2 )
=-75.948/41.504
=-182.99 %

where

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROC % →
What does a ROC % of -182.99% mean?
Inovio Pharmaceuticals (FRA:GBM) has a ROC % of -182.99% as of Mar. 2026. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Inovio Pharmaceuticals and its competitors.
Is Inovio Pharmaceuticals' ROC % too high?
Inovio Pharmaceuticals' current ROC % is -182.99%. Overall, Inovio Pharmaceuticals has a GF Score™ of 43/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Inovio Pharmaceuticals' ROC % compare to NRXS and FBIO?
Inovio Pharmaceuticals' ROC % of -182.99% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROC % for a Biotechnology company?
A good ROC % depends on the Biotechnology industry context. However, ROC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROC % mean?
A high ROC % can signal that a stock is expensive relative to its fundamentals. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Inovio Pharmaceuticals and its competitors. Inovio Pharmaceuticals's current ROC % is -182.99%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Inovio Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Inovio Pharmaceuticals (FRA:GBM) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.19, compared to a current price of €1.02 — trading 434.2% above its estimated fair value. The current ROC % is -182.99%. Inovio Pharmaceuticals' overall GF Score™ is 43/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROC % calculated?
ROC % is calculated from a company's financial statements. For Inovio Pharmaceuticals (FRA:GBM), the current ROC % is -182.99% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Inovio Pharmaceuticals (FRA:GBM) Overvalued in 2026?

Based on GuruFocus' analysis, Inovio Pharmaceuticals stock appears to be overvalued. The current stock price of €1.02 is trading 434.2% above its estimated GF Value™ of €0.19. GuruFocus considers Inovio Pharmaceuticals to be Significantly Overvalued.

Key valuation signals for FRA:GBM:

  • ROC %: -182.99%
  • GF Value™: €0.19 vs. price of €1.02 (434.2% above fair value)
  • GF Score™: 43/100 with 4 warning signs

No single metric tells the full story. See the FRA:GBM stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Inovio Pharmaceuticals Business Description

Address 660 West Germantown Pike, Suite 110, Plymouth Meeting, PA, USA, 19462
Inovio Pharmaceuticals Inc is a clinical-stage biotechnology company focused on developing and commercializing DNA medicines to help treat and protect people from diseases associated with human papillomavirus (HPV), cancer and infectious diseases. INOVIO's platform harnesses the power of in vivo protein production, featuring optimized design and delivery of DNA medicines that teach the body to manufacture its own disease-fighting tools. Its candidate is INO-3107 for the treatment of recurrent respiratory papillomatosis (RRP), a chronic, rare and debilitating disease of the respiratory tract caused by HPV infection. In its completed Phase 1/2 clinical trial of INO-3107 for the treatment of HPV-6 and HPV-11-associated RRP.
43GF Score

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ROC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€1.02
Price
€0.19
GF Value