KLRS (Kalaris Therapeutics) ROC %: -556.55% (As of Mar. 2026)

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KLRS Kalaris Therapeutics Inc KLRS
12 GF Score
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What is Kalaris Therapeutics ROC %?

Kalaris Therapeutics KLRS +0.76% 12 ROC % is -556.55% as of Mar. 2026. GuruFocus rates KLRS with a GF Score™ of 12/100.

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. Kalaris Therapeutics's annualized return on capital (ROC %) for the quarter that ended in Mar. 2026 was -556.55%.

As of today (2026-08-11), Kalaris Therapeutics's WACC % is 10.54%. Kalaris Therapeutics's ROC % is -960.65% (calculated using TTM income statement data). Kalaris Therapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Kalaris Therapeutics  (NAS:KLRS) ROC % Explanation

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Kalaris Therapeutics's WACC % is 10.54%. Kalaris Therapeutics's ROC % is -960.65% (calculated using TTM income statement data). Kalaris Therapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Kalaris Therapeutics ROC % Related Terms


Kalaris Therapeutics ROC % Historical Data

* Premium members only.

The historical data trend for Kalaris Therapeutics's ROC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Kalaris Therapeutics ROC % Chart

Kalaris Therapeutics Annual Data
Trend Dec22 Dec23 Dec24 Dec25
ROC %
-4,731.76 -3,221.05 -403.60 -308.31

Kalaris Therapeutics Quarterly Data
Dec22 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only -311.32 -2,893.12 -1,625.65 -935.46 -556.55
KLRS
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Kalaris Therapeutics Inc KLRS
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Kalaris Therapeutics ROC % Calculation

Kalaris Therapeutics's annualized Return on Capital (ROC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-46.152 * ( 1 - 0% )/( (25.095 + 4.844)/ 2 )
=-46.152/14.9695
=-308.31 %

where

Kalaris Therapeutics's annualized Return on Capital (ROC %) for the quarter that ended in Mar. 2026 is calculated as:

ROC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=-47.332 * ( 1 - 0% )/( (4.844 + 12.165)/ 2 )
=-47.332/8.5045
=-556.55 %

where

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROC % →
What does a ROC % of -556.55% mean?
Kalaris Therapeutics (KLRS) has a ROC % of -556.55% as of Mar. 2026. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Kalaris Therapeutics and its competitors.
Is Kalaris Therapeutics' ROC % too high?
Kalaris Therapeutics' current ROC % is -556.55%. Overall, Kalaris Therapeutics has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Kalaris Therapeutics' ROC % compare to HRTX and VRCA?
Kalaris Therapeutics' ROC % of -556.55% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROC % for a Biotechnology company?
A good ROC % depends on the Biotechnology industry context. However, ROC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROC % mean?
A high ROC % can signal that a stock is expensive relative to its fundamentals. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Kalaris Therapeutics and its competitors. Kalaris Therapeutics's current ROC % is -556.55%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Kalaris Therapeutics stock overvalued right now?
Kalaris Therapeutics (KLRS) has a current ROC % of -556.55%. The current ROC % is -556.55%. Kalaris Therapeutics' overall GF Score™ is 12/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROC % calculated?
ROC % is calculated from a company's financial statements. For Kalaris Therapeutics (KLRS), the current ROC % is -556.55% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Kalaris Therapeutics Business Description

Address 400 Connell Drive, Suite 5500, Berkeley Heights, NJ, USA, 07922
Kalaris Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing and commercializing therapeutics for prevalent retinal diseases. The company is developing TH103, a novel, clinical-stage anti-vascular endothelial growth factor VEGF drug, engineered to potentially provide longer-lasting and increased anti-VEGF activity in patients with exudative and neovascular retinal diseases. TH103 is a fully humanized recombinant fusion protein, functioning as a decoy receptor (a VEGF trap), leveraging salient molecular properties of the human body's native, highest affinity VEGF receptor 1.
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ROC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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