ACRS (Aclaris Therapeutics) ROE % Adjusted to Book Value: -17.66% (As of Mar. 2026)


ACRS Aclaris Therapeutics Inc ACRS
38 GF Score
Price $5.00
GF Value $0.45
Valuation Significantly Overvalued
! 10 Warning Signs
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What is Aclaris Therapeutics ROE % Adjusted to Book Value?

Aclaris Therapeutics ACRS +1.73% 38 ROE % Adjusted to Book Value is -17.66% as of Mar. 2026. GuruFocus rates ACRS with a GF Score™ of 38/100 and a GF Value™ of $0.45 (Significantly Overvalued). The stock has 10 warning signs investors should review.

Aclaris Therapeutics's ROE % for the quarter that ended in Mar. 2026 was -64.28%. Aclaris Therapeutics's PB Ratio for the quarter that ended in Mar. 2026 was 3.64. Aclaris Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -17.66%.


Aclaris Therapeutics ROE % Adjusted to Book Value Related Terms


Aclaris Therapeutics ROE % Adjusted to Book Value Historical Data

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The historical data trend for Aclaris Therapeutics's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Aclaris Therapeutics ROE % Adjusted to Book Value Chart

Aclaris Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -17.15 -8.27 -106.13 -49.10 -14.26

Aclaris Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -35.03 -38.25 -27.15 -20.16 -17.66

ACRS vs RLMD, GYRE, SGP: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Aclaris Therapeutics's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Aclaris Therapeutics ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Aclaris Therapeutics's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Aclaris Therapeutics's ROE % Adjusted to Book Value falls into.


ACRS
38GF Score
Aclaris Therapeutics Inc ACRS
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Aclaris Therapeutics ROE % Adjusted to Book Value Calculation

Aclaris Therapeutics's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-50.20% / 3.52
=-14.26%

Aclaris Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-64.28% / 3.64
=-17.66%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -17.66% mean?
Aclaris Therapeutics (ACRS) has a ROE % Adjusted to Book Value of -17.66% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Aclaris Therapeutics and its competitors.
Is Aclaris Therapeutics' ROE % Adjusted to Book Value too high?
Aclaris Therapeutics' current ROE % Adjusted to Book Value is -17.66%. Overall, Aclaris Therapeutics has a GF Score™ of 38/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Aclaris Therapeutics' ROE % Adjusted to Book Value compare to RLMD and GYRE?
Aclaris Therapeutics' ROE % Adjusted to Book Value of -17.66% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Aclaris Therapeutics and its competitors. Aclaris Therapeutics's current ROE % Adjusted to Book Value is -17.66%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Aclaris Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Aclaris Therapeutics (ACRS) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.45, compared to a current price of $5.00 — trading 1011.1% above its estimated fair value. The current ROE % Adjusted to Book Value is -17.66%. Aclaris Therapeutics' overall GF Score™ is 38/100 with 10 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Aclaris Therapeutics (ACRS), the current ROE % Adjusted to Book Value is -17.66% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Aclaris Therapeutics (ACRS) Overvalued in 2026?

Based on GuruFocus' analysis, Aclaris Therapeutics stock appears to be overvalued. The current stock price of $5.00 is trading 1011.1% above its estimated GF Value™ of $0.45. GuruFocus considers Aclaris Therapeutics to be Significantly Overvalued.

Key valuation signals for ACRS:

  • ROE % Adjusted to Book Value: -17.66%
  • GF Value™: $0.45 vs. price of $5.00 (1011.1% above fair value)
  • GF Score™: 38/100 with 10 warning signs

No single metric tells the full story. See the ACRS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Aclaris Therapeutics Business Description

Other Exchanges 0H8T:UK8AT:Germany
Address 701 Lee Road, Suite 103, Wayne, PA, USA, 19087
Aclaris Therapeutics Inc is a clinical-stage biopharmaceutical company. It focuses on developing novel drug candidates for immuno-inflammatory diseases using its proprietary KINect drug discovery platform. The company's pipeline consists of the following key product candidates: Bosakitug (ATI-045), an investigational, novel, humanized anti-TSLP monoclonal antibody being developed for patients with severe asthma, COPD, and chronic rhinosinusitis with nasal polyps; ATI-2138, being developed for the potential treatment of T cell-mediated autoimmune diseases; and ATI-052 and ATI-9494. Additionally, it has an investigational product candidate, Lepzacitinib (ATI-1777), which is being focused upon as a potential treatment for atopic dermatitis and potentially other dermatologic conditions.
38GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$5.00
Price
$0.45
GF Value