ARCT (Arcturus Therapeutics Holdings) ROE % Adjusted to Book Value: -46.28% (As of Mar. 2026)


ARCT Arcturus Therapeutics Holdings Inc ARCT
54 GF Score
Price $7.04
GF Value $4.41
Valuation Significantly Overvalued
! 4 Warning Signs
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What is Arcturus Therapeutics Holdings ROE % Adjusted to Book Value?

Arcturus Therapeutics Holdings ARCT +3.23% 54 ROE % Adjusted to Book Value is -46.28% as of Mar. 2026. GuruFocus rates ARCT with a GF Score™ of 54/100 and a GF Value™ of $4.41 (Significantly Overvalued). The stock has 4 warning signs investors should review.

Arcturus Therapeutics Holdings's ROE % for the quarter that ended in Mar. 2026 was -53.22%. Arcturus Therapeutics Holdings's PB Ratio for the quarter that ended in Mar. 2026 was 1.15. Arcturus Therapeutics Holdings's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -46.28%.


Arcturus Therapeutics Holdings ROE % Adjusted to Book Value Related Terms


Arcturus Therapeutics Holdings ROE % Adjusted to Book Value Historical Data

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The historical data trend for Arcturus Therapeutics Holdings's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Arcturus Therapeutics Holdings ROE % Adjusted to Book Value Chart

Arcturus Therapeutics Holdings Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -15.23 2.25 -3.56 -16.40 -35.70

Arcturus Therapeutics Holdings Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -19.28 -10.33 -10.54 -65.49 -46.28

ARCT vs YDES, RNAC, RNA: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Arcturus Therapeutics Holdings's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Arcturus Therapeutics Holdings ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Arcturus Therapeutics Holdings's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Arcturus Therapeutics Holdings's ROE % Adjusted to Book Value falls into.


ARCT
54GF Score
Arcturus Therapeutics Holdings Inc ARCT
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Arcturus Therapeutics Holdings ROE % Adjusted to Book Value Calculation

Arcturus Therapeutics Holdings's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-28.92% / 0.81
=-35.70%

Arcturus Therapeutics Holdings's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-53.22% / 1.15
=-46.28%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -46.28% mean?
Arcturus Therapeutics Holdings (ARCT) has a ROE % Adjusted to Book Value of -46.28% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Arcturus Therapeutics Holdings and its competitors.
Is Arcturus Therapeutics Holdings' ROE % Adjusted to Book Value too high?
Arcturus Therapeutics Holdings' current ROE % Adjusted to Book Value is -46.28%. Overall, Arcturus Therapeutics Holdings has a GF Score™ of 54/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Arcturus Therapeutics Holdings' ROE % Adjusted to Book Value compare to YDES and RNAC?
Arcturus Therapeutics Holdings' ROE % Adjusted to Book Value of -46.28% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Arcturus Therapeutics Holdings and its competitors. Arcturus Therapeutics Holdings's current ROE % Adjusted to Book Value is -46.28%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Arcturus Therapeutics Holdings stock overvalued right now?
Based on GuruFocus' analysis, Arcturus Therapeutics Holdings (ARCT) is currently considered Significantly Overvalued. The stock's GF Value™ is $4.41, compared to a current price of $7.04 — trading 59.5% above its estimated fair value. The current ROE % Adjusted to Book Value is -46.28%. Arcturus Therapeutics Holdings' overall GF Score™ is 54/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Arcturus Therapeutics Holdings (ARCT), the current ROE % Adjusted to Book Value is -46.28% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Arcturus Therapeutics Holdings (ARCT) Overvalued in 2026?

Based on GuruFocus' analysis, Arcturus Therapeutics Holdings stock appears to be overvalued. The current stock price of $7.04 is trading 59.5% above its estimated GF Value™ of $4.41. GuruFocus considers Arcturus Therapeutics Holdings to be Significantly Overvalued.

Key valuation signals for ARCT:

  • ROE % Adjusted to Book Value: -46.28%
  • GF Value™: $4.41 vs. price of $7.04 (59.5% above fair value)
  • GF Score™: 54/100 with 4 warning signs

No single metric tells the full story. See the ARCT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Arcturus Therapeutics Holdings Business Description

Address 10285 Science Center Drive, San Diego, CA, USA, 92121
Arcturus Therapeutics Holdings Inc is an RNA medicines company focused on the development of infectious disease vaccines and opportunities within liver and respiratory rare diseases. It operates in one business segment, which includes all activities related to the discovery, development, and commercialization of messenger RNA medicines. The company's pipeline includes LUNAR-OTC and LUNAR-CF. Its Vaccine candidates include LUNAR-FLU, KOSTAIVE XBB.1.5, KOSTAIVE, and Others.
54GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$7.04
Price
$4.41
GF Value