Clinuvel Pharmaceuticals (ASX:CUV) ROE % Adjusted to Book Value: 3.40% (As of Dec. 2025)


ASX:CUV Clinuvel Pharmaceuticals Ltd ASX:CUV
81 GF Score
Price A$10.28
GF Value A$17.71
Valuation Significantly Undervalued
! 2 Warning Signs
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What is Clinuvel Pharmaceuticals ROE % Adjusted to Book Value?

Clinuvel Pharmaceuticals ASX:CUV -0.68% 81 ROE % Adjusted to Book Value is 3.40% as of Dec. 2025. GuruFocus rates ASX:CUV with a GF Score™ of 81/100 and a GF Value™ of A$17.71 (Significantly Undervalued). The stock has 2 warning signs investors should review.

Clinuvel Pharmaceuticals's ROE % for the quarter that ended in Dec. 2025 was 8.53%. Clinuvel Pharmaceuticals's PB Ratio for the quarter that ended in Dec. 2025 was 2.51. Clinuvel Pharmaceuticals's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 was 3.40%.


Clinuvel Pharmaceuticals ROE % Adjusted to Book Value Related Terms


Clinuvel Pharmaceuticals ROE % Adjusted to Book Value Historical Data

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The historical data trend for Clinuvel Pharmaceuticals's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Clinuvel Pharmaceuticals ROE % Adjusted to Book Value Chart

Clinuvel Pharmaceuticals Annual Data
Trend Jun16 Jun17 Jun18 Jun19 Jun20 Jun21 Jun22 Jun23 Jun24 Jun25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only 1.87 3.19 3.93 5.12 7.55

Clinuvel Pharmaceuticals Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.84 6.83 4.82 8.93 3.40

ASX:CUV vs VRTX, REGN, ALNY: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Clinuvel Pharmaceuticals's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Clinuvel Pharmaceuticals ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Clinuvel Pharmaceuticals's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Clinuvel Pharmaceuticals's ROE % Adjusted to Book Value falls into.


ASX:CUV
81GF Score
Clinuvel Pharmaceuticals Ltd ASX:CUV
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Clinuvel Pharmaceuticals ROE % Adjusted to Book Value Calculation

Clinuvel Pharmaceuticals's ROE % Adjusted to Book Value for the fiscal year that ended in Jun. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=16.30% / 2.16
=7.55%

Clinuvel Pharmaceuticals's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=8.53% / 2.51
=3.40%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of 3.40% mean?
Clinuvel Pharmaceuticals (ASX:CUV) has a ROE % Adjusted to Book Value of 3.40% as of Dec. 2025. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Clinuvel Pharmaceuticals and its competitors.
Is Clinuvel Pharmaceuticals' ROE % Adjusted to Book Value too high?
Clinuvel Pharmaceuticals' current ROE % Adjusted to Book Value is 3.40%. Overall, Clinuvel Pharmaceuticals has a GF Score™ of 81/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Clinuvel Pharmaceuticals' ROE % Adjusted to Book Value compare to VRTX and REGN?
Clinuvel Pharmaceuticals' ROE % Adjusted to Book Value of 3.40% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Clinuvel Pharmaceuticals and its competitors. Clinuvel Pharmaceuticals's current ROE % Adjusted to Book Value is 3.40%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Clinuvel Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Clinuvel Pharmaceuticals (ASX:CUV) is currently considered Significantly Undervalued. The stock's GF Value™ is A$17.71, compared to a current price of A$10.28 — trading 42% below its estimated fair value. The current ROE % Adjusted to Book Value is 3.40%. Clinuvel Pharmaceuticals' overall GF Score™ is 81/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Clinuvel Pharmaceuticals (ASX:CUV), the current ROE % Adjusted to Book Value is 3.40% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Clinuvel Pharmaceuticals (ASX:CUV) Overvalued in 2026?

Based on GuruFocus' analysis, Clinuvel Pharmaceuticals stock appears to be undervalued. The current stock price of A$10.28 is trading 42% below its estimated GF Value™ of A$17.71. GuruFocus considers Clinuvel Pharmaceuticals to be Significantly Undervalued.

Key valuation signals for ASX:CUV:

  • ROE % Adjusted to Book Value: 3.40%
  • GF Value™: A$17.71 vs. price of A$10.28 (42% below fair value)
  • GF Score™: 81/100 with 2 warning signs

No single metric tells the full story. See the ASX:CUV stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Clinuvel Pharmaceuticals Business Description

Address 535 Bourke Street, Level 22, Melbourne, VIC, AUS, 3000
Clinuvel distributes a single product, Scenesse, the only approved treatment for phototoxic reactions specifically associated with a rare genetic disease called erythropoietic protoporphyria. EPP causes extreme pain or burns from brief exposure to light, affecting a patient's quality of life. Scenesse is a patented dissolvable implant, comparable in size with a rice grain, injected underneath the skin roughly every three months for ongoing protection. The implant controls the release of a synthetic drug which promotes the production of more melanin, thereby reducing pain and increasing tolerance for light exposure. The majority of Clinuvel's earnings stem from Europe and the US.
81GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

A$10.28
Price
A$17.71
GF Value