AYTU (Aytu BioPharma) ROE % Adjusted to Book Value: -109.73% (As of Mar. 2026)


AYTU Aytu BioPharma Inc AYTU
40 GF Score
Price $2.19
GF Value $0.84
Valuation Significantly Overvalued
! 3 Warning Signs
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What is Aytu BioPharma ROE % Adjusted to Book Value?

Aytu BioPharma AYTU +0.92% 40 ROE % Adjusted to Book Value is -109.73% as of Mar. 2026. GuruFocus rates AYTU with a GF Score™ of 40/100 and a GF Value™ of $0.84 (Significantly Overvalued). The stock has 3 warning signs investors should review.

Aytu BioPharma's ROE % for the quarter that ended in Mar. 2026 was -91.08%. Aytu BioPharma's PB Ratio for the quarter that ended in Mar. 2026 was 0.83. Aytu BioPharma's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -109.73%.


Aytu BioPharma ROE % Adjusted to Book Value Related Terms


Aytu BioPharma ROE % Adjusted to Book Value Historical Data

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The historical data trend for Aytu BioPharma's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Aytu BioPharma ROE % Adjusted to Book Value Chart

Aytu BioPharma Annual Data
Trend Jun16 Jun17 Jun18 Jun19 Jun20 Jun21 Jun22 Jun23 Jun24 Jun25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -50.12 -199.37 -185.27 -74.98 -56.41

Aytu BioPharma Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 231.71 -285.77 46.64 -115.01 -109.73

AYTU vs TXMD, CPHI, RMTI: ROE % Adjusted to Book Value Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Aytu BioPharma's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Aytu BioPharma ROE % Adjusted to Book Value vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Aytu BioPharma's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Aytu BioPharma's ROE % Adjusted to Book Value falls into.


AYTU
40GF Score
Aytu BioPharma Inc AYTU
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Aytu BioPharma ROE % Adjusted to Book Value Calculation

Aytu BioPharma's ROE % Adjusted to Book Value for the fiscal year that ended in Jun. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-58.10% / 1.03
=-56.41%

Aytu BioPharma's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-91.08% / 0.83
=-109.73%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -109.73% mean?
Aytu BioPharma (AYTU) has a ROE % Adjusted to Book Value of -109.73% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Aytu BioPharma and its competitors.
Is Aytu BioPharma's ROE % Adjusted to Book Value too high?
Aytu BioPharma's current ROE % Adjusted to Book Value is -109.73%. Overall, Aytu BioPharma has a GF Score™ of 40/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Aytu BioPharma's ROE % Adjusted to Book Value compare to TXMD and CPHI?
Aytu BioPharma's ROE % Adjusted to Book Value of -109.73% can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Drug Manufacturers company?
A good ROE % Adjusted to Book Value depends on the Drug Manufacturers industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Aytu BioPharma and its competitors. Aytu BioPharma's current ROE % Adjusted to Book Value is -109.73%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Aytu BioPharma stock overvalued right now?
Based on GuruFocus' analysis, Aytu BioPharma (AYTU) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.84, compared to a current price of $2.19 — trading 160.7% above its estimated fair value. The current ROE % Adjusted to Book Value is -109.73%. Aytu BioPharma's overall GF Score™ is 40/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Aytu BioPharma (AYTU), the current ROE % Adjusted to Book Value is -109.73% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Aytu BioPharma (AYTU) Overvalued in 2026?

Based on GuruFocus' analysis, Aytu BioPharma stock appears to be overvalued. The current stock price of $2.19 is trading 160.7% above its estimated GF Value™ of $0.84. GuruFocus considers Aytu BioPharma to be Significantly Overvalued.

Key valuation signals for AYTU:

  • ROE % Adjusted to Book Value: -109.73%
  • GF Value™: $0.84 vs. price of $2.19 (160.7% above fair value)
  • GF Score™: 40/100 with 3 warning signs

No single metric tells the full story. See the AYTU stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Aytu BioPharma Business Description

Address 7900 East Union Avenue, Suite 920, Denver, CO, USA, 80237
Aytu BioPharma Inc is a specialty pharmaceutical company with a commercial portfolio of prescription therapeutics and consumer health products. The company's primary prescription products treat attention deficit hyperactivity disorder and other common pediatric conditions. It is building a complementary therapeutic development pipeline, including a prospective treatment (AR101/enzastaurin) for vascular Ehlers-Danlos Syndrome, a rare genetic disease resulting in high morbidity and a significantly shortened lifespan. The company operates one business segment consisting of various prescription pharmaceutical products sold through third parties.
40GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.19
Price
$0.84
GF Value