CANF (Can Fite Biopharma) ROE % Adjusted to Book Value: -215.55% (As of Dec. 2025)


CANF Can Fite Biopharma Ltd CANF
60 GF Score
Price $2.99
GF Value $5.98
Valuation Possible Value Trap
! 4 Warning Signs
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What is Can Fite Biopharma ROE % Adjusted to Book Value?

Can Fite Biopharma CANF 60 ROE % Adjusted to Book Value is -215.55% as of Dec. 2025. GuruFocus rates CANF with a GF Score™ of 60/100 and a GF Value™ of $5.98 (Possible Value Trap). The stock has 4 warning signs investors should review.

Can Fite Biopharma's ROE % for the quarter that ended in Dec. 2025 was -202.62%. Can Fite Biopharma's PB Ratio for the quarter that ended in Dec. 2025 was 0.94. Can Fite Biopharma's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 was -215.55%.


Can Fite Biopharma ROE % Adjusted to Book Value Related Terms


Can Fite Biopharma ROE % Adjusted to Book Value Historical Data

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The historical data trend for Can Fite Biopharma's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Can Fite Biopharma ROE % Adjusted to Book Value Chart

Can Fite Biopharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -50.55 -28.93 -89.06 -45.43 -189.62

Can Fite Biopharma Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -65.07 -31.23 -66.75 -61.07 -215.55

CANF vs VRTX, REGN, ALNY: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Can Fite Biopharma's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Can Fite Biopharma ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Can Fite Biopharma's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Can Fite Biopharma's ROE % Adjusted to Book Value falls into.


CANF
60GF Score
Can Fite Biopharma Ltd CANF
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Can Fite Biopharma ROE % Adjusted to Book Value Calculation

Can Fite Biopharma's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-178.24% / 0.94
=-189.62%

Can Fite Biopharma's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-202.62% / 0.94
=-215.55%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -215.55% mean?
Can Fite Biopharma (CANF) has a ROE % Adjusted to Book Value of -215.55% as of Dec. 2025. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Can Fite Biopharma and its competitors.
Is Can Fite Biopharma's ROE % Adjusted to Book Value too high?
Can Fite Biopharma's current ROE % Adjusted to Book Value is -215.55%. Overall, Can Fite Biopharma has a GF Score™ of 60/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Can Fite Biopharma's ROE % Adjusted to Book Value compare to VRTX and REGN?
Can Fite Biopharma's ROE % Adjusted to Book Value of -215.55% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Can Fite Biopharma and its competitors. Can Fite Biopharma's current ROE % Adjusted to Book Value is -215.55%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Can Fite Biopharma stock overvalued right now?
Based on GuruFocus' analysis, Can Fite Biopharma (CANF) is currently considered Possible Value Trap. The stock's GF Value™ is $5.98, compared to a current price of $2.99 — trading 50% below its estimated fair value. The current ROE % Adjusted to Book Value is -215.55%. Can Fite Biopharma's overall GF Score™ is 60/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Can Fite Biopharma (CANF), the current ROE % Adjusted to Book Value is -215.55% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Can Fite Biopharma (CANF) Overvalued in 2026?

Based on GuruFocus' analysis, Can Fite Biopharma stock appears to be undervalued. The current stock price of $2.99 is trading 50% below its estimated GF Value™ of $5.98. GuruFocus considers Can Fite Biopharma to be Possible Value Trap.

Key valuation signals for CANF:

  • ROE % Adjusted to Book Value: -215.55%
  • GF Value™: $5.98 vs. price of $2.99 (50% below fair value)
  • GF Score™: 60/100 with 4 warning signs

No single metric tells the full story. See the CANF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Can Fite Biopharma Business Description

Other Exchanges CANF:Israel
Address 26 Ben Gurion Street, Ramat Gan, ISR, 5257346
Can Fite Biopharma Ltd is a clinical-stage biopharmaceutical company. The company focuses on developing orally bioavailable small-molecule drugs targeting the A3 adenosine receptor for treating cancer, inflammatory diseases, liver disorders, and related conditions. It has a pipeline of proprietary drug candidates in Phase II and Phase III clinical development. The company's platform targets the A3 adenosine receptor (A3AR), which is more expressed in inflammatory and cancerous cells than in normal cells. Its pipeline drugs include Namodenoson, Piclidenoson, CF602, and Cannabinoids.
60GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.99
Price
$5.98
GF Value