CYYNF (Cynata Therapeutics) ROE % Adjusted to Book Value: -6.91% (As of Dec. 2025)


What is Cynata Therapeutics ROE % Adjusted to Book Value?

Cynata Therapeutics CYYNF -95.96% ROE % Adjusted to Book Value is -6.91% as of Dec. 2025. The stock has 1 warning sign investors should review.

Cynata Therapeutics's ROE % for the quarter that ended in Dec. 2025 was -115.13%. Cynata Therapeutics's PB Ratio for the quarter that ended in Dec. 2025 was 16.67. Cynata Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 was -6.91%.

Cynata Therapeutics ROE % Adjusted to Book Value Related Terms

Cynata Therapeutics ROE % Adjusted to Book Value Historical Data

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The historical data trend for Cynata Therapeutics's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cynata Therapeutics ROE % Adjusted to Book Value Chart

Cynata Therapeutics Annual Data
Trend Jun16 Jun17 Jun18 Jun19 Jun20 Jun21 Jun22 Jun23 Jun24 Jun25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -11.47 -7.82 -17.92 -11.47 -29.89

Cynata Therapeutics Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -39.82 -15.10 -12.90 -28.42 -6.91

CYYNF vs VRTX, REGN, ALNY: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Cynata Therapeutics's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Cynata Therapeutics ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cynata Therapeutics's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Cynata Therapeutics's ROE % Adjusted to Book Value falls into.


Cynata Therapeutics ROE % Adjusted to Book Value Calculation

Cynata Therapeutics's ROE % Adjusted to Book Value for the fiscal year that ended in Jun. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-140.76% / 4.71
=-29.89%

Cynata Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-115.13% / 16.67
=-6.91%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -6.91% mean?
Cynata Therapeutics (CYYNF) has a ROE % Adjusted to Book Value of -6.91% as of Dec. 2025. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Cynata Therapeutics and its competitors.
Is Cynata Therapeutics' ROE % Adjusted to Book Value too high?
Cynata Therapeutics' current ROE % Adjusted to Book Value is -6.91%.
How does Cynata Therapeutics' ROE % Adjusted to Book Value compare to VRTX and REGN?
Cynata Therapeutics' ROE % Adjusted to Book Value of -6.91% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Cynata Therapeutics and its competitors. Cynata Therapeutics's current ROE % Adjusted to Book Value is -6.91%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cynata Therapeutics stock overvalued right now?
Cynata Therapeutics (CYYNF) has a current ROE % Adjusted to Book Value of -6.91%. The current ROE % Adjusted to Book Value is -6.91%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Cynata Therapeutics (CYYNF), the current ROE % Adjusted to Book Value is -6.91% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Cynata Therapeutics Business Description

Other Exchanges 51S:GermanyCYP:Australia
Address 100 Cubitt Street, Level 3, Cremorne, VIC, AUS, 3121
Cynata Therapeutics Ltd is engaged in the development and commercialization of a proprietary mesenchymal stem cell (MSC) technology for potential human therapeutic use, which is branded as Cymerus manufacturing platform. There are currently three active clinical trials taking place using Cymerus technology, which are attempting to treat osteoarthritis and others.