Kala Bio (FRA:27F) ROE % Adjusted to Book Value: -262.11% (As of Mar. 2026)

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FRA:27F Kala Bio Inc FRA:27F
18 GF Score
Price €3.40
! 2 Warning Signs
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What is Kala Bio ROE % Adjusted to Book Value?

Kala Bio FRA:27F 18 ROE % Adjusted to Book Value is -262.11% as of Mar. 2026. GuruFocus rates FRA:27F with a GF Score™ of 18/100. The stock has 2 warning signs investors should review.

Kala Bio's ROE % for the quarter that ended in Mar. 2026 was -73.39%. Kala Bio's PB Ratio for the quarter that ended in Mar. 2026 was 0.28. Kala Bio's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -262.11%.

Kala Bio ROE % Adjusted to Book Value Related Terms

Kala Bio ROE % Adjusted to Book Value Historical Data

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The historical data trend for Kala Bio's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Kala Bio ROE % Adjusted to Book Value Chart

Kala Bio Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -2,889.22 -3,226.63 -6,243.40 -5,631.86 -5,191.80

Kala Bio Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2,985.85 0.00 0.00 Negative Equity -262.11

FRA:27F vs MGX, HYPD, VERU: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Kala Bio's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Kala Bio ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Kala Bio's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Kala Bio's ROE % Adjusted to Book Value falls into.


FRA:27F
18GF Score
Kala Bio Inc FRA:27F
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Kala Bio ROE % Adjusted to Book Value Calculation

Kala Bio's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-259.59% / 0.05
=-5,191.80%

Kala Bio's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-73.39% / 0.28
=-262.11%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -262.11% mean?
Kala Bio (FRA:27F) has a ROE % Adjusted to Book Value of -262.11% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Kala Bio and its competitors.
Is Kala Bio's ROE % Adjusted to Book Value too high?
Kala Bio's current ROE % Adjusted to Book Value is -262.11%. Overall, Kala Bio has a GF Score™ of 18/100, reflecting its overall financial health beyond just this single metric.
How does Kala Bio's ROE % Adjusted to Book Value compare to MGX and HYPD?
Kala Bio's ROE % Adjusted to Book Value of -262.11% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Kala Bio and its competitors. Kala Bio's current ROE % Adjusted to Book Value is -262.11%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Kala Bio stock overvalued right now?
Kala Bio (FRA:27F) has a current ROE % Adjusted to Book Value of -262.11%. The current ROE % Adjusted to Book Value is -262.11%. Kala Bio's overall GF Score™ is 18/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Kala Bio (FRA:27F), the current ROE % Adjusted to Book Value is -262.11% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Kala Bio Business Description

Other Exchanges KALA:USA0JQ2:UK27F:Germany
Address 1167 Massachusetts Avenue, Arlington, MA, USA, 02476
Kala Bio Inc is a clinical-stage biopharmaceutical company dedicated to the research, development and commercialization of inventive therapies for rare and severe diseases of the front and back of the eye. It main product candidate, KPI-012, is a human MSC-S, which contains numerous human-derived biofactors, such as growth factors, protease inhibitors, matrix proteins, and neurotrophic factors that can potentially correct the impaired corneal healing that is an underlying etiology of multiple severe ocular diseases. Its MSC-S platform is for retinal degenerative diseases, such as Retinitis Pigmentosa and Stargardt Disease.
18GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€3.40
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