GRAIL (GRAL) ROE % Adjusted to Book Value: -17.27% (As of Mar. 2026)


GRAL GRAIL Inc GRAL
12 GF Score
Price $65.92
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What is GRAIL ROE % Adjusted to Book Value?

GRAIL GRAL -0.98% 12 ROE % Adjusted to Book Value is -17.27% as of Mar. 2026. GuruFocus rates GRAL with a GF Score™ of 12/100. The stock has 2 warning signs investors should review.

GRAIL's ROE % for the quarter that ended in Mar. 2026 was -14.68%. GRAIL's PB Ratio for the quarter that ended in Mar. 2026 was 0.85. GRAIL's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -17.27%.

GRAIL ROE % Adjusted to Book Value Related Terms

GRAIL ROE % Adjusted to Book Value Historical Data

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The historical data trend for GRAIL's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

GRAIL ROE % Adjusted to Book Value Chart

GRAIL Annual Data
Trend Dec18 Dec19 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial 0.00 0.00 0.00 -274.67 -11.99

GRAIL Quarterly Data
Dec18 Dec19 Jun20 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -46.70 -24.11 -16.45 -12.29 -17.27

GRAL vs VCYT, ADPT, TWST: ROE % Adjusted to Book Value Comparison

For the Diagnostics & Research subindustry, GRAIL's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

GRAIL ROE % Adjusted to Book Value vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, GRAIL's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where GRAIL's ROE % Adjusted to Book Value falls into.


GRAL
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GRAIL Inc GRAL
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GRAIL ROE % Adjusted to Book Value Calculation

GRAIL's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-16.07% / 1.34
=-11.99%

GRAIL's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-14.68% / 0.85
=-17.27%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -17.27% mean?
GRAIL (GRAL) has a ROE % Adjusted to Book Value of -17.27% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on GRAIL and its competitors.
Is GRAIL's ROE % Adjusted to Book Value too high?
GRAIL's current ROE % Adjusted to Book Value is -17.27%. Overall, GRAIL has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does GRAIL's ROE % Adjusted to Book Value compare to VCYT and ADPT?
GRAIL's ROE % Adjusted to Book Value of -17.27% can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Medical Diagnostics & Research company?
A good ROE % Adjusted to Book Value depends on the Medical Diagnostics & Research industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on GRAIL and its competitors. GRAIL's current ROE % Adjusted to Book Value is -17.27%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is GRAIL stock overvalued right now?
GRAIL (GRAL) has a current ROE % Adjusted to Book Value of -17.27%. The current ROE % Adjusted to Book Value is -17.27%. GRAIL's overall GF Score™ is 12/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For GRAIL (GRAL), the current ROE % Adjusted to Book Value is -17.27% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

GRAIL Business Description

Other Exchanges NL0:Germany
Address 1525 O’Brien Drive, Menlo Park, CA, USA, 94025
GRAIL Inc is a healthcare company focused on developing technologies for early cancer detection. The company has developed a multi-cancer early detection blood test that has the ability to detect all types of cancer, across all stages. It operates in one reportable operating segment which provides multi-cancer early detection testing and service.
12GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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