PLRZ (Polyrizon) ROE % Adjusted to Book Value: -49.37% (As of Dec. 2025)


PLRZ Polyrizon Ltd PLRZ
14 GF Score
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What is Polyrizon ROE % Adjusted to Book Value?

Polyrizon PLRZ +1.28% 14 ROE % Adjusted to Book Value is -49.37% as of Dec. 2025. GuruFocus rates PLRZ with a GF Score™ of 14/100. The stock has 4 warning signs investors should review.

Polyrizon's ROE % for the quarter that ended in Dec. 2025 was -32.09%. Polyrizon's PB Ratio for the quarter that ended in Dec. 2025 was 0.65. Polyrizon's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 was -49.37%.

Polyrizon ROE % Adjusted to Book Value Related Terms

Polyrizon ROE % Adjusted to Book Value Historical Data

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The historical data trend for Polyrizon's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Polyrizon ROE % Adjusted to Book Value Chart

Polyrizon Annual Data
Trend Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
0.00 0.00 -32.78 -39.05

Polyrizon Semi-Annual Data
Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Adjusted to Book Value Get a 7-Day Free Trial 0.00 0.00 -39.34 -12.46 -49.37

PLRZ vs SKYE, NEUP, LGVN: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Polyrizon's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Polyrizon ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Polyrizon's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Polyrizon's ROE % Adjusted to Book Value falls into.


PLRZ
14GF Score
Polyrizon Ltd PLRZ
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Polyrizon ROE % Adjusted to Book Value Calculation

Polyrizon's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-25.38% / 0.65
=-39.05%

Polyrizon's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-32.09% / 0.65
=-49.37%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -49.37% mean?
Polyrizon (PLRZ) has a ROE % Adjusted to Book Value of -49.37% as of Dec. 2025. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Polyrizon and its competitors.
Is Polyrizon's ROE % Adjusted to Book Value too high?
Polyrizon's current ROE % Adjusted to Book Value is -49.37%. Overall, Polyrizon has a GF Score™ of 14/100, reflecting its overall financial health beyond just this single metric.
How does Polyrizon's ROE % Adjusted to Book Value compare to SKYE and NEUP?
Polyrizon's ROE % Adjusted to Book Value of -49.37% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Polyrizon and its competitors. Polyrizon's current ROE % Adjusted to Book Value is -49.37%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Polyrizon stock overvalued right now?
Polyrizon (PLRZ) has a current ROE % Adjusted to Book Value of -49.37%. The current ROE % Adjusted to Book Value is -49.37%. Polyrizon's overall GF Score™ is 14/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Polyrizon (PLRZ), the current ROE % Adjusted to Book Value is -49.37% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Polyrizon Business Description

Address 5 Ha-Tidhar Street, Raanana, ISR, 4366507
Polyrizon Ltd is a clinical development stage biotech company specializing in the development of nasal gels to provide preventative treatment to protect against a wide cross-section of viruses, including certain variants of COVID-19 that are also considered to cause more infections and spread faster than the original strain of the virus (the CDC expects that additional variants of the virus will continue to occur), influenza, allergens, and other toxins. The company's technology platforms are Capture & Contain and Trap & Target.
14GF Score

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