SANA (Sana Biotechnology) ROE % Adjusted to Book Value: -27.50% (As of Jun. 2026)

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SANA Sana Biotechnology Inc SANA
32 GF Score
Price $3.85
! 1 Warning Sign
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What is Sana Biotechnology ROE % Adjusted to Book Value?

Sana Biotechnology SANA -1.66% 32 ROE % Adjusted to Book Value is -27.50% as of Jun. 2026. GuruFocus rates SANA with a GF Score™ of 32/100. The stock has 1 warning sign investors should review.

Sana Biotechnology's ROE % for the quarter that ended in Jun. 2026 was -185.93%. Sana Biotechnology's PB Ratio for the quarter that ended in Jun. 2026 was 6.76. Sana Biotechnology's ROE % Adjusted to Book Value for the quarter that ended in Jun. 2026 was -27.50%.

Sana Biotechnology ROE % Adjusted to Book Value Related Terms

Sana Biotechnology ROE % Adjusted to Book Value Historical Data

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The historical data trend for Sana Biotechnology's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Sana Biotechnology ROE % Adjusted to Book Value Chart

Sana Biotechnology Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial -58.94 -29.07 -25.62 -67.92 -17.59

Sana Biotechnology Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -44.11 -22.24 -19.57 -20.68 -27.50

SANA vs APMD, ODTX, CRVS: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Sana Biotechnology's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Sana Biotechnology ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Sana Biotechnology's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Sana Biotechnology's ROE % Adjusted to Book Value falls into.


SANA
32GF Score
Sana Biotechnology Inc SANA
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Sana Biotechnology ROE % Adjusted to Book Value Calculation

Sana Biotechnology's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-118.70% / 6.75
=-17.59%

Sana Biotechnology's ROE % Adjusted to Book Value for the quarter that ended in Jun. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-185.93% / 6.76
=-27.50%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -27.50% mean?
Sana Biotechnology (SANA) has a ROE % Adjusted to Book Value of -27.50% as of Jun. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Sana Biotechnology and its competitors.
Is Sana Biotechnology's ROE % Adjusted to Book Value too high?
Sana Biotechnology's current ROE % Adjusted to Book Value is -27.50%. Overall, Sana Biotechnology has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Sana Biotechnology's ROE % Adjusted to Book Value compare to APMD and ODTX?
Sana Biotechnology's ROE % Adjusted to Book Value of -27.50% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Sana Biotechnology and its competitors. Sana Biotechnology's current ROE % Adjusted to Book Value is -27.50%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Sana Biotechnology stock overvalued right now?
Sana Biotechnology (SANA) has a current ROE % Adjusted to Book Value of -27.50%. The current ROE % Adjusted to Book Value is -27.50%. Sana Biotechnology's overall GF Score™ is 32/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Sana Biotechnology (SANA), the current ROE % Adjusted to Book Value is -27.50% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Sana Biotechnology Business Description

Address 188 East Blaine Street, Suite 350, Seattle, WA, USA, 98102
Sana Biotechnology Inc is a biotechnology company. The company develops engineered cells as medicines and therapies to treat diseases. It is engaged in developing cell engineering programs across a broad array of therapeutic areas with unmet treatment needs, including oncology, diabetes, B-cell-mediated autoimmune, and central nervous system (CNS) disorders, among others. Its pipeline of product candidates comprises SC291, SC262, UP421, and others.
32GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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