ZLAB (Zai Lab) ROE % Adjusted to Book Value: -9.41% (As of Mar. 2026)

Zai Lab ZLAB -4.81% 64 ROE % Adjusted to Book Value is -9.41% as of Mar. 2026. GuruFocus rates ZLAB with a GF Score™ of 64/100 and a GF Value™ of $30.30 (Possible Value Trap). The stock has 8 warning signs investors should review.

Zai Lab's ROE % for the quarter that ended in Mar. 2026 was -29.63%. Zai Lab's PB Ratio for the quarter that ended in Mar. 2026 was 3.15. Zai Lab's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -9.41%.

Zai Lab ROE % Adjusted to Book Value Related Terms

Zai Lab ROE % Adjusted to Book Value Historical Data

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The historical data trend for Zai Lab's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Zai Lab ROE % Adjusted to Book Value Chart

Zai Lab Annual Data

Trend

Dec16

Dec17

Dec18

Dec19

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

ROE % Adjusted to Book Value

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-12.71

-12.96

-10.88

-9.35

-8.26

Zai Lab Quarterly Data
	Jun21	Sep21	Dec21	Mar22	Jun22	Sep22	Dec22	Mar23	Jun23	Sep23	Dec23	Mar24	Jun24	Sep24	Dec24	Mar25	Jun25	Sep25	Dec25	Mar26
ROE % Adjusted to Book Value	Get a 7-Day Free Trial															-4.86	-4.19	-3.76	-10.01	-9.41

ZLAB vs TYRA, TRVI, OCUL: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Zai Lab's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Zai Lab ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Zai Lab's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Zai Lab's ROE % Adjusted to Book Value falls into.

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64GF Score

Zai Lab Ltd ZLAB

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Zai Lab ROE % Adjusted to Book Value Calculation

Zai Lab's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value	=	ROE %	/	PB Ratio
	=	-22.56%	/	2.73
	=	-8.26%

Zai Lab's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value	=	ROE %	/	PB Ratio
	=	-29.63%	/	3.15
	=	-9.41%

Frequently Asked Questions Learn more about ROE % Adjusted to Book Value →

What does a ROE % Adjusted to Book Value of -9.41% mean?

Zai Lab (ZLAB) has a ROE % Adjusted to Book Value of -9.41% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Zai Lab and its competitors.

Is Zai Lab's ROE % Adjusted to Book Value too high?

Zai Lab's current ROE % Adjusted to Book Value is -9.41%. Overall, Zai Lab has a GF Score™ of 64/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.

How does Zai Lab's ROE % Adjusted to Book Value compare to TYRA and TRVI?

Zai Lab's ROE % Adjusted to Book Value of -9.41% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good ROE % Adjusted to Book Value for a Biotechnology company?

A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high ROE % Adjusted to Book Value mean?

A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Zai Lab and its competitors. Zai Lab's current ROE % Adjusted to Book Value is -9.41%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is Zai Lab stock overvalued right now?

Based on GuruFocus' analysis, Zai Lab (ZLAB) is currently considered Possible Value Trap. The stock's GF Value™ is $30.30, compared to a current price of $17.63 — trading 41.8% below its estimated fair value. The current ROE % Adjusted to Book Value is -9.41%. Zai Lab's overall GF Score™ is 64/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is ROE % Adjusted to Book Value calculated?

ROE % Adjusted to Book Value is calculated from a company's financial statements. For Zai Lab (ZLAB), the current ROE % Adjusted to Book Value is -9.41% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Zai Lab (ZLAB) Overvalued in 2026?

Based on GuruFocus' analysis, Zai Lab stock appears to be undervalued. The current stock price of $17.63 is trading 41.8% below its estimated GF Value™ of $30.30. GuruFocus considers Zai Lab to be Possible Value Trap.

Key valuation signals for ZLAB:

ROE % Adjusted to Book Value: -9.41%
GF Value™: $30.30 vs. price of $17.63 (41.8% below fair value)
GF Score™: 64/100 with 8 warning signs

No single metric tells the full story. See the ZLAB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Zai Lab Business Description

Industry Healthcare Biotechnology

Comparable Companies TYRA TRVI OCUL AUPH NTLA VRDN SION STOK RXRX RAPP VRTX REGN XBRU:UCB XBRU:ARGX XKRX:207940 ALNY RVMD ASX:CSL ONC XKRX:068270

Other Exchanges 09688:Hong Kong 1ZLB:Germany

Address 899 Halei Road, Building B, Pudong, Shanghai, CHN, 201203

Website https://www.zailaboratory.com

Zai Lab Ltd is a biopharmaceutical company focusing on discovering or licensing, developing, and commercializing proprietary therapeutics that address areas of unmet medical need including in the fields of oncology, autoimmune and infectious diseases. Zai Lab has a diverse pipeline of potentially first-in-class product candidates developed through in-house R&D and global partnerships. The company has successfully commercialized several products in China, including Zejula, Optune, Qinlock, and Nuzyra, with plans for further expansion The pipeline of proprietary drug candidates of the company includes ZL-1222, ZL-1311, ZL-6201 and many others.

64GF Score

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$17.63

Price

$30.30

GF Value

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