DCOY (Decoy Therapeutics) ROE %: -182.27% (As of Mar. 2026)


DCOY Decoy Therapeutics Inc DCOY
23 GF Score
Price $6.02
! 3 Warning Signs
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What is Decoy Therapeutics ROE %?

Decoy Therapeutics DCOY -6.47% 23 ROE % is -182.27% as of Mar. 2026. GuruFocus rates DCOY with a GF Score™ of 23/100. The stock has 3 warning signs investors should review. Among 1,252 Biotechnology companies, Decoy Therapeutics ranks worse than 95.61% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Decoy Therapeutics's annualized net income for the quarter that ended in Mar. 2026 was $-8.90 Mil. Decoy Therapeutics's average Total Stockholders Equity over the quarter that ended in Mar. 2026 was $4.88 Mil. Therefore, Decoy Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 was -182.27%.

The historical rank and industry rank for Decoy Therapeutics's ROE % or its related term are showing as below:

DCOY' s ROE % Range Over the Past 10 Years
Min: -492   Med: -96.05   Max: -41.94
Current: -492

During the past 12 years, Decoy Therapeutics's highest ROE % was -41.94%. The lowest was -492.00%. And the median was -96.05%.

DCOY's ROE % is ranked worse than
95.61% of 1252 companies
in the Biotechnology industry
Industry Median: -38.145 vs DCOY: -492.00

Decoy Therapeutics  (NAS:DCOY) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-8.9/4.883
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-8.9 / 0)*(0 / 9.74)*(9.74 / 4.883)
=Net Margin %*Asset Turnover*Equity Multiplier
=N/A %*0*1.9947
=ROA %*Equity Multiplier
=N/A %*1.9947
=-182.27 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-8.9/4.883
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-8.9 / -8.9) * (-8.9 / -9.136) * (-9.136 / 0) * (0 / 9.74) * (9.74 / 4.883)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1 * 0.9742 * N/A % * 0 * 1.9947
=-182.27 %

Note: The net income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Decoy Therapeutics ROE % Related Terms


Decoy Therapeutics ROE % Historical Data

* Premium members only.

The historical data trend for Decoy Therapeutics's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Decoy Therapeutics ROE % Chart

Decoy Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -41.94 -128.73 -160.07 -164.02 -338.28

Decoy Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -869.12 0.00 -204.33 -708.53 -182.27

DCOY vs ARTL, RNAZ, GLMD: ROE % Comparison

For the Biotechnology subindustry, Decoy Therapeutics's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Decoy Therapeutics ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Decoy Therapeutics's ROE % distribution charts can be found below:

* The bar in red indicates where Decoy Therapeutics's ROE % falls into.


DCOY
23GF Score
Decoy Therapeutics Inc DCOY
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Decoy Therapeutics ROE % Calculation

Decoy Therapeutics's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-12.518/( (1.512+5.889)/ 2 )
=-12.518/3.7005
=-338.28 %

Decoy Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 is calculated as

ROE %=Net Income (Q: Mar. 2026 )/( (Total Stockholders Equity (Q: Dec. 2025 )+Total Stockholders Equity (Q: Mar. 2026 ))/ count )
=-8.9/( (5.889+3.877)/ 2 )
=-8.9/4.883
=-182.27 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -182.27% mean?
Decoy Therapeutics (DCOY) has a ROE % of -182.27% as of Mar. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Decoy Therapeutics and its competitors. According to the industry distribution chart, Decoy Therapeutics ranks #1197 out of 1252 companies in the Biotechnology industry, placing it in the top 95.6%.
Is Decoy Therapeutics' ROE % too high?
Decoy Therapeutics' current ROE % is -182.27%. Based on the distribution chart, Decoy Therapeutics ranks #1197 out of 1252 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Decoy Therapeutics has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does Decoy Therapeutics' ROE % compare to ARTL and RNAZ?
According to the Biotechnology industry distribution chart, Decoy Therapeutics ranks #1197 out of 1252 companies for ROE %. This places Decoy Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Decoy Therapeutics and its competitors. Decoy Therapeutics's current ROE % is -182.27%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Decoy Therapeutics stock overvalued right now?
Decoy Therapeutics (DCOY) has a current ROE % of -182.27%. The current ROE % is -182.27%. Decoy Therapeutics' overall GF Score™ is 23/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Decoy Therapeutics (DCOY), the current ROE % is -182.27% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Decoy Therapeutics Business Description

Address 2450 Holcombe Boulevard, Suite X, Houston, TX, USA, 77021
Decoy Therapeutics Inc is a pre-clinical stage biotechnology company focused on advancing its pipeline of peptide conjugate therapeutics engineered through its proprietary IMP3ACT platform. The IMP3ACT platform represents a paradigm shift in peptide conjugate drug discovery and manufacturing, leveraging machine learning (ML) and artificial intelligence (AI" tools alongside high-speed synthesis techniques to rapidly engineer, optimize and manufacture peptide conjugates that target serious unmet medical needs. The company manages its business in one operating segment, focused on the discovery and development therapeutics for patients with high, unmet medical needs. Its pipeline programs include: Pan-Coronavirus; and Tripledemic.
23GF Score

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ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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