Cartesian Therapeutics (FRA:1S70) ROE %: 0.00% (As of Mar. 2026)

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FRA:1S70 Cartesian Therapeutics Inc FRA:1S70
27 GF Score
Price €6.60
GF Value €0.23
Valuation Significantly Overvalued
! 4 Warning Signs
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What is Cartesian Therapeutics ROE %?

Cartesian Therapeutics FRA:1S70 +2.33% 27 ROE % is 0.00% as of Mar. 2026. GuruFocus rates FRA:1S70 with a GF Score™ of 27/100 and a GF Value™ of €0.23 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 1,250 Biotechnology companies, Cartesian Therapeutics ranks worse than 79999.92% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Cartesian Therapeutics's annualized net income for the quarter that ended in Mar. 2026 was €-135.57 Mil. Cartesian Therapeutics's average Total Stockholders Equity over the quarter that ended in Mar. 2026 was €-117.97 Mil. Therefore, Cartesian Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 was N/A%.

The historical rank and industry rank for Cartesian Therapeutics's ROE % or its related term are showing as below:

During the past 12 years, Cartesian Therapeutics's highest ROE % was 60.82%. The lowest was -3,716.01%. And the median was -281.64%.

FRA:1S70's ROE % is not ranked *
in the Biotechnology industry.
Industry Median: -38.53
* Ranked among companies with meaningful ROE % only.

Cartesian Therapeutics  (FRA:1S70) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-135.568/-117.9655
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-135.568 / 0.268)*(0.268 / 251.2965)*(251.2965 / -117.9655)
=Net Margin %*Asset Turnover*Equity Multiplier
=-50585.07 %*0.0011*N/A
=ROA %*Equity Multiplier
=-55.64 %*N/A
=N/A %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-135.568/-117.9655
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-135.568 / -135.568) * (-135.568 / -91.688) * (-91.688 / 0.268) * (0.268 / 251.2965) * (251.2965 / -117.9655)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1 * 1.4786 * -34211.94 % * 0.0011 * N/A
=N/A %

Note: The net income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Cartesian Therapeutics ROE % Related Terms


Cartesian Therapeutics ROE % Historical Data

* Premium members only.

The historical data trend for Cartesian Therapeutics's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cartesian Therapeutics ROE % Chart

Cartesian Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -886.28 61.56 0.00 0.00 0.00

Cartesian Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 Negative Equity 0.00 0.00 0.00

FRA:1S70 vs LYEL, ALXO, ARMP: ROE % Comparison

For the Biotechnology subindustry, Cartesian Therapeutics's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cartesian Therapeutics ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cartesian Therapeutics's ROE % distribution charts can be found below:

* The bar in red indicates where Cartesian Therapeutics's ROE % falls into.


FRA:1S70
27GF Score
Cartesian Therapeutics Inc FRA:1S70
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Cartesian Therapeutics ROE % Calculation

Cartesian Therapeutics's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-111.278/( (-6.496+-107.809)/ 2 )
=-111.278/-57.1525
=N/A %

Cartesian Therapeutics's annualized ROE % for the quarter that ended in Mar. 2026 is calculated as

ROE %=Net Income (Q: Mar. 2026 )/( (Total Stockholders Equity (Q: Dec. 2025 )+Total Stockholders Equity (Q: Mar. 2026 ))/ count )
=-135.568/( (-107.809+-128.122)/ 2 )
=-135.568/-117.9655
=N/A %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. ROE % is displayed in the 30-year financial page.

* Note that if the average Total Stockholders Equity is zero or negative, then ROE % would be considered meaningless and hence not be calculated.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of 0.00% mean?
Cartesian Therapeutics (FRA:1S70) has a ROE % of 0.00% as of Mar. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Cartesian Therapeutics and its competitors. According to the industry distribution chart, Cartesian Therapeutics ranks #999999 out of 1250 companies in the Biotechnology industry.
Is Cartesian Therapeutics' ROE % too high?
Cartesian Therapeutics' current ROE % is 0.00%. Based on the distribution chart, Cartesian Therapeutics ranks #999999 out of 1250 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Cartesian Therapeutics has a GF Score™ of 27/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Cartesian Therapeutics' ROE % compare to LYEL and ALXO?
According to the Biotechnology industry distribution chart, Cartesian Therapeutics ranks #999999 out of 1250 companies for ROE %. This places Cartesian Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Cartesian Therapeutics and its competitors. Cartesian Therapeutics's current ROE % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cartesian Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Cartesian Therapeutics (FRA:1S70) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.23, compared to a current price of €6.60 — trading 2769.6% above its estimated fair value. The current ROE % is 0.00%. Cartesian Therapeutics' overall GF Score™ is 27/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Cartesian Therapeutics (FRA:1S70), the current ROE % is 0.00% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Cartesian Therapeutics (FRA:1S70) Overvalued in 2026?

Based on GuruFocus' analysis, Cartesian Therapeutics stock appears to be overvalued. The current stock price of €6.60 is trading 2769.6% above its estimated GF Value™ of €0.23. GuruFocus considers Cartesian Therapeutics to be Significantly Overvalued.

Key valuation signals for FRA:1S70:

  • ROE %: 0.00%
  • GF Value™: €0.23 vs. price of €6.60 (2769.6% above fair value)
  • GF Score™: 27/100 with 4 warning signs

No single metric tells the full story. See the FRA:1S70 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Cartesian Therapeutics Business Description

Other Exchanges RNAC:USA
Address 7495 New Horizon Way, Frederick, MD, USA, 21703
Cartesian Therapeutics Inc is a clinical-stage biopharmaceutical company pioneering cell therapy for the treatment of autoimmune diseases. The company uses technology and a manufacturing platform to introduce mRNA into cells to provide a therapeutic effect to patients suffering from a variety of autoimmune conditions. Unlike DNA, mRNA degrades naturally over time without integrating into the cell's genetic material.
27GF Score

Get the complete analysis for FRA:1S70

ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€6.60
Price
€0.23
GF Value