THX Pharma (FRA:3VG) ROE %: -762.09% (As of Dec. 2025)


FRA:3VG THX Pharma FRA:3VG
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What is THX Pharma ROE %?

THX Pharma FRA:3VG +1.10% 30 ROE % is -762.09% as of Dec. 2025. GuruFocus rates FRA:3VG with a GF Score™ of 30/100. The stock has 1 warning sign investors should review. Among 1,256 Biotechnology companies, THX Pharma ranks worse than 95.54% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. THX Pharma's annualized net income for the quarter that ended in Dec. 2025 was €-3.86 Mil. THX Pharma's average Total Stockholders Equity over the quarter that ended in Dec. 2025 was €0.51 Mil. Therefore, THX Pharma's annualized ROE % for the quarter that ended in Dec. 2025 was -762.09%.

The historical rank and industry rank for THX Pharma's ROE % or its related term are showing as below:

FRA:3VG' s ROE % Range Over the Past 10 Years
Min: -624.78   Med: -81.1   Max: -21.87
Current: -482.64

During the past 11 years, THX Pharma's highest ROE % was -21.87%. The lowest was -624.78%. And the median was -81.10%.

FRA:3VG's ROE % is ranked worse than
95.54% of 1256 companies
in the Biotechnology industry
Industry Median: -38.26 vs FRA:3VG: -482.64

THX Pharma  (FRA:3VG) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=-3.86/0.5065
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-3.86 / 0)*(0 / 7.5375)*(7.5375 / 0.5065)
=Net Margin %*Asset Turnover*Equity Multiplier
=N/A %*0*14.8815
=ROA %*Equity Multiplier
=N/A %*14.8815
=-762.09 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=-3.86/0.5065
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-3.86 / -5.694) * (-5.694 / -5.796) * (-5.796 / 0) * (0 / 7.5375) * (7.5375 / 0.5065)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 0.6779 * 0.9824 * N/A % * 0 * 14.8815
=-762.09 %

Note: The net income data used here is two times the semi-annual (Dec. 2025) net income data. The Revenue data used here is two times the semi-annual (Dec. 2025) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


THX Pharma ROE % Related Terms


THX Pharma ROE % Historical Data

* Premium members only.

The historical data trend for THX Pharma's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

THX Pharma ROE % Chart

THX Pharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -79.65 -82.55 -171.77 -624.78 -482.64

THX Pharma Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -261.95 18.21 0.00 0.00 -762.09

FRA:3VG vs VRTX, REGN, ALNY: ROE % Comparison

For the Biotechnology subindustry, THX Pharma's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


THX Pharma ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, THX Pharma's ROE % distribution charts can be found below:

* The bar in red indicates where THX Pharma's ROE % falls into.


FRA:3VG
30GF Score
THX Pharma FRA:3VG
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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THX Pharma ROE % Calculation

THX Pharma's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-3.002/( (-1.657+2.901)/ 2 )
=-3.002/0.622
=-482.64 %

THX Pharma's annualized ROE % for the quarter that ended in Dec. 2025 is calculated as

ROE %=Net Income (Q: Dec. 2025 )/( (Total Stockholders Equity (Q: Jun. 2025 )+Total Stockholders Equity (Q: Dec. 2025 ))/ count )
=-3.86/( (-1.888+2.901)/ 2 )
=-3.86/0.5065
=-762.09 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is two times the semi-annual (Dec. 2025) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -762.09% mean?
THX Pharma (FRA:3VG) has a ROE % of -762.09% as of Dec. 2025. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on THX Pharma and its competitors. According to the industry distribution chart, THX Pharma ranks #1200 out of 1256 companies in the Biotechnology industry, placing it in the top 95.5%.
Is THX Pharma's ROE % too high?
THX Pharma's current ROE % is -762.09%. Based on the distribution chart, THX Pharma ranks #1200 out of 1256 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, THX Pharma has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does THX Pharma's ROE % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, THX Pharma ranks #1200 out of 1256 companies for ROE %. This places THX Pharma in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on THX Pharma and its competitors. THX Pharma's current ROE % is -762.09%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is THX Pharma stock overvalued right now?
THX Pharma (FRA:3VG) has a current ROE % of -762.09%. The current ROE % is -762.09%. THX Pharma's overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For THX Pharma (FRA:3VG), the current ROE % is -762.09% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

THX Pharma Business Description

Other Exchanges ALTHX:France3VG:Germany
Address 60 avenue Rockefeller, Pepiniere Laennec, Lyon, FRA, 69008
THX Pharma Formerly Theranexus SA is a France based biopharmaceutical company. It is engaged in developing drug candidates to be used in the treatment of central nervous system (CNS) disorders. The company's therapeutics platform is based on simultaneously targeting neurons and glial cells by creating and developing innovative combinations of two distinct drugs: a CNS drug targeting neuronal activity; and a drug targeting glial cells. The drug candidates of the organization are THN102 to treat excessive daytime sleepiness in Parkinson's disease, THN201 for the treatment of neurocognitive disorders in Alzheimer's disease and THN101 for neuropathic pain.
30GF Score

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ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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