CytoMed Therapeutics (FRA:F98) ROE %: -50.16% (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

FRA:F98 CytoMed Therapeutics Ltd FRA:F98
19 GF Score
Price €0.76
! 2 Warning Signs
View Full Analysis

What is CytoMed Therapeutics ROE %?

CytoMed Therapeutics FRA:F98 -9.58% 19 ROE % is -50.16% as of Dec. 2025. GuruFocus rates FRA:F98 with a GF Score™ of 19/100. The stock has 2 warning signs investors should review. Among 1,251 Biotechnology companies, CytoMed Therapeutics ranks worse than 57.95% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. CytoMed Therapeutics's annualized net income for the quarter that ended in Dec. 2025 was €-2.30 Mil. CytoMed Therapeutics's average Total Stockholders Equity over the quarter that ended in Dec. 2025 was €4.58 Mil. Therefore, CytoMed Therapeutics's annualized ROE % for the quarter that ended in Dec. 2025 was -50.16%.

The historical rank and industry rank for CytoMed Therapeutics's ROE % or its related term are showing as below:

FRA:F98' s ROE % Range Over the Past 10 Years
Min: -406.72   Med: -101.61   Max: -24.72
Current: -53.74

During the past 6 years, CytoMed Therapeutics's highest ROE % was -24.72%. The lowest was -406.72%. And the median was -101.61%.

FRA:F98's ROE % is ranked worse than
57.95% of 1251 companies
in the Biotechnology industry
Industry Median: -38.61 vs FRA:F98: -53.74

CytoMed Therapeutics  (FRA:F98) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=-2.298/4.581
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-2.298 / 0.224)*(0.224 / 5.4665)*(5.4665 / 4.581)
=Net Margin %*Asset Turnover*Equity Multiplier
=-1025.89 %*0.041*1.1933
=ROA %*Equity Multiplier
=-42.06 %*1.1933
=-50.16 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=-2.298/4.581
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-2.298 / -2.318) * (-2.318 / -2.916) * (-2.916 / 0.224) * (0.224 / 5.4665) * (5.4665 / 4.581)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 0.9914 * 0.7949 * -1301.79 % * 0.041 * 1.1933
=-50.16 %

Note: The net income data used here is two times the semi-annual (Dec. 2025) net income data. The Revenue data used here is two times the semi-annual (Dec. 2025) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


CytoMed Therapeutics ROE % Related Terms


CytoMed Therapeutics ROE % Historical Data

* Premium members only.

The historical data trend for CytoMed Therapeutics's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CytoMed Therapeutics ROE % Chart

CytoMed Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial -134.82 -208.99 -69.81 -25.28 -49.35

CytoMed Therapeutics Semi-Annual Data
Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only -32.44 -20.32 -30.32 -54.31 -50.16

FRA:F98 vs LEXX, INAB, TRAW: ROE % Comparison

For the Biotechnology subindustry, CytoMed Therapeutics's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


CytoMed Therapeutics ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, CytoMed Therapeutics's ROE % distribution charts can be found below:

* The bar in red indicates where CytoMed Therapeutics's ROE % falls into.


FRA:F98
19GF Score
CytoMed Therapeutics Ltd FRA:F98
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

CytoMed Therapeutics ROE % Calculation

CytoMed Therapeutics's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-2.633/( (6.341+4.33)/ 2 )
=-2.633/5.3355
=-49.35 %

CytoMed Therapeutics's annualized ROE % for the quarter that ended in Dec. 2025 is calculated as

ROE %=Net Income (Q: Dec. 2025 )/( (Total Stockholders Equity (Q: Jun. 2025 )+Total Stockholders Equity (Q: Dec. 2025 ))/ count )
=-2.298/( (4.832+4.33)/ 2 )
=-2.298/4.581
=-50.16 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is two times the semi-annual (Dec. 2025) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -50.16% mean?
CytoMed Therapeutics (FRA:F98) has a ROE % of -50.16% as of Dec. 2025. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on CytoMed Therapeutics and its competitors. According to the industry distribution chart, CytoMed Therapeutics ranks #725 out of 1251 companies in the Biotechnology industry, placing it in the top 58%.
Is CytoMed Therapeutics' ROE % too high?
CytoMed Therapeutics' current ROE % is -50.16%. Based on the distribution chart, CytoMed Therapeutics ranks #725 out of 1251 companies in the Biotechnology industry, which is below the industry midpoint. Overall, CytoMed Therapeutics has a GF Score™ of 19/100, reflecting its overall financial health beyond just this single metric.
How does CytoMed Therapeutics' ROE % compare to LEXX and INAB?
According to the Biotechnology industry distribution chart, CytoMed Therapeutics ranks #725 out of 1251 companies for ROE %. This places CytoMed Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on CytoMed Therapeutics and its competitors. CytoMed Therapeutics's current ROE % is -50.16%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CytoMed Therapeutics stock overvalued right now?
CytoMed Therapeutics (FRA:F98) has a current ROE % of -50.16%. The current ROE % is -50.16%. CytoMed Therapeutics' overall GF Score™ is 19/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For CytoMed Therapeutics (FRA:F98), the current ROE % is -50.16% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

CytoMed Therapeutics Business Description

Other Exchanges GDTC:USA
Address 1 Commonwealth Lane, No. 08-22 One Commonwealth, Singapore, SGP, 149544
CytoMed Therapeutics Ltd is a pre-clinical biopharmaceutical company focused on harnessing its proprietary technologies to create novel cell-based immunotherapies for the treatment of human cancers. The company's segment include: the business of innate immune cell-based immunotherapy, pluripotent stem cell-based therapy and undertaking the research and development of immune cell and stem cell-based therapy; and the business of processing and banking of cells including cord blood stem cells, research and development on cord blood derived cell-based therapy. Geographically, the company operates in Singapore and Malaysia which is the majority revenue generator.
19GF Score

Get the complete analysis for FRA:F98

ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€0.76
Price