Shanghai Henlius Biotech (HKSE:02696) ROE %: 23.83% (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

HKSE:02696 Shanghai Henlius Biotech Inc HKSE:02696
67 GF Score
Price HK$67.30
GF Value HK$30.91
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is Shanghai Henlius Biotech ROE %?

Shanghai Henlius Biotech HKSE:02696 -1.10% 67 ROE % is 23.83% as of Dec. 2025. GuruFocus rates HKSE:02696 with a GF Score™ of 67/100 and a GF Value™ of HK$30.91 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 1,250 Biotechnology companies, Shanghai Henlius Biotech ranks better than 93.76% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Shanghai Henlius Biotech's annualized net income for the quarter that ended in Dec. 2025 was HK$965 Mil. Shanghai Henlius Biotech's average Total Stockholders Equity over the quarter that ended in Dec. 2025 was HK$4,050 Mil. Therefore, Shanghai Henlius Biotech's annualized ROE % for the quarter that ended in Dec. 2025 was 23.83%.

The historical rank and industry rank for Shanghai Henlius Biotech's ROE % or its related term are showing as below:

HKSE:02696' s ROE % Range Over the Past 10 Years
Min: -57.44   Med: -29.28   Max: 31.2
Current: 24.1

During the past 9 years, Shanghai Henlius Biotech's highest ROE % was 31.20%. The lowest was -57.44%. And the median was -29.28%.

HKSE:02696's ROE % is ranked better than
93.76% of 1250 companies
in the Biotechnology industry
Industry Median: -38.755 vs HKSE:02696: 24.10

Shanghai Henlius Biotech  (HKSE:02696) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=965.342/4050.268
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(965.342 / 8499.948)*(8499.948 / 13140.225)*(13140.225 / 4050.268)
=Net Margin %*Asset Turnover*Equity Multiplier
=11.36 %*0.6469*3.2443
=ROA %*Equity Multiplier
=7.35 %*3.2443
=23.83 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=965.342/4050.268
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (965.342 / 923.524) * (923.524 / 1052.662) * (1052.662 / 8499.948) * (8499.948 / 13140.225) * (13140.225 / 4050.268)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1.0453 * 0.8773 * 12.38 % * 0.6469 * 3.2443
=23.83 %

Note: The net income data used here is two times the semi-annual (Dec. 2025) net income data. The Revenue data used here is two times the semi-annual (Dec. 2025) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Shanghai Henlius Biotech ROE % Related Terms


Shanghai Henlius Biotech ROE % Historical Data

* Premium members only.

The historical data trend for Shanghai Henlius Biotech's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Shanghai Henlius Biotech ROE % Chart

Shanghai Henlius Biotech Annual Data
Trend Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial Premium Member Only -36.49 -33.47 28.27 31.20 24.07

Shanghai Henlius Biotech Semi-Annual Data
Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 29.99 32.15 30.94 24.57 23.83

HKSE:02696 vs VRTX, REGN, RVMD: ROE % Comparison

For the Biotechnology subindustry, Shanghai Henlius Biotech's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Shanghai Henlius Biotech ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Shanghai Henlius Biotech's ROE % distribution charts can be found below:

* The bar in red indicates where Shanghai Henlius Biotech's ROE % falls into.


HKSE:02696
67GF Score
Shanghai Henlius Biotech Inc HKSE:02696
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Shanghai Henlius Biotech ROE % Calculation

Shanghai Henlius Biotech's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=913.654/( (3217.559+4375.23)/ 2 )
=913.654/3796.3945
=24.07 %

Shanghai Henlius Biotech's annualized ROE % for the quarter that ended in Dec. 2025 is calculated as

ROE %=Net Income (Q: Dec. 2025 )/( (Total Stockholders Equity (Q: Jun. 2025 )+Total Stockholders Equity (Q: Dec. 2025 ))/ count )
=965.342/( (3725.306+4375.23)/ 2 )
=965.342/4050.268
=23.83 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is two times the semi-annual (Dec. 2025) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of 23.83% mean?
Shanghai Henlius Biotech (HKSE:02696) has a ROE % of 23.83% as of Dec. 2025. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Shanghai Henlius Biotech and its competitors. According to the industry distribution chart, Shanghai Henlius Biotech ranks #78 out of 1250 companies in the Biotechnology industry, placing it in the top 6.2%.
Is Shanghai Henlius Biotech's ROE % too high?
Shanghai Henlius Biotech's current ROE % is 23.83%. Based on the distribution chart, Shanghai Henlius Biotech ranks #78 out of 1250 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Shanghai Henlius Biotech has a GF Score™ of 67/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Shanghai Henlius Biotech's ROE % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Shanghai Henlius Biotech ranks #78 out of 1250 companies for ROE %. This places Shanghai Henlius Biotech in the top 6% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Shanghai Henlius Biotech and its competitors. Shanghai Henlius Biotech's current ROE % is 23.83%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Shanghai Henlius Biotech stock overvalued right now?
Based on GuruFocus' analysis, Shanghai Henlius Biotech (HKSE:02696) is currently considered Significantly Overvalued. The stock's GF Value™ is HK$30.91, compared to a current price of HK$67.30 — trading 117.7% above its estimated fair value. The current ROE % is 23.83%. Shanghai Henlius Biotech's overall GF Score™ is 67/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Shanghai Henlius Biotech (HKSE:02696), the current ROE % is 23.83% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Shanghai Henlius Biotech (HKSE:02696) Overvalued in 2026?

Based on GuruFocus' analysis, Shanghai Henlius Biotech stock appears to be overvalued. The current stock price of HK$67.30 is trading 117.7% above its estimated GF Value™ of HK$30.91. GuruFocus considers Shanghai Henlius Biotech to be Significantly Overvalued.

Key valuation signals for HKSE:02696:

  • ROE %: 23.83%
  • GF Value™: HK$30.91 vs. price of HK$67.30 (117.7% above fair value)
  • GF Score™: 67/100 with 4 warning signs

No single metric tells the full story. See the HKSE:02696 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Shanghai Henlius Biotech Business Description

Other Exchanges 2E8:Germany
Address B8 Building, No. 188 Yizhou Road, 11th Floor, Xuhui District, Shanghai, CHN, 200233
Shanghai Henlius Biotech Inc is a biopharmaceutical company in China with the vision to offer affordable and biologics for patients with a focus on oncology and autoimmune diseases. The Group is engaged in biopharmaceutical R&D, biopharmaceutical services, and biopharmaceutical production and sales. It operates in Mainland China, Asia Pacific (excluding Mainland China), North America, South America, Oceania, and Europe. The company products include HLX01 Rituximab, HLX02(trastuzumab), and others.
67GF Score

Get the complete analysis for HKSE:02696

ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

HK$67.30
Price
HK$30.91
GF Value