LTGO (Latigo Biotherapeutics) ROE %: 0.00% (As of Dec. 2025)

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LTGO Latigo Biotherapeutics Inc LTGO
8 GF Score
Price $18.56
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What is Latigo Biotherapeutics ROE %?

Latigo Biotherapeutics LTGO +1.70% 8 ROE % is 0.00% as of Dec. 2025. GuruFocus rates LTGO with a GF Score™ of 8/100. Among 1,248 Biotechnology companies, Latigo Biotherapeutics ranks worse than 80128.13% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Latigo Biotherapeutics's annualized net income for the quarter that ended in Dec. 2025 was $-109.17 Mil. Latigo Biotherapeutics's average Total Stockholders Equity over the quarter that ended in Dec. 2025 was $-180.64 Mil. Therefore, Latigo Biotherapeutics's annualized ROE % for the quarter that ended in Dec. 2025 was N/A%.

The historical rank and industry rank for Latigo Biotherapeutics's ROE % or its related term are showing as below:

LTGO's ROE % is not ranked *
in the Biotechnology industry.
Industry Median: -39.22
* Ranked among companies with meaningful ROE % only.

Latigo Biotherapeutics  (NAS:LTGO) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=-109.167/-180.6365
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-109.167 / 0)*(0 / 49.19)*(49.19 / -180.6365)
=Net Margin %*Asset Turnover*Equity Multiplier
=N/A %*0*N/A
=ROA %*Equity Multiplier
=N/A %*N/A
=N/A %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=-109.167/-180.6365
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-109.167 / -109.167) * (-109.167 / -110.392) * (-110.392 / 0) * (0 / 49.19) * (49.19 / -180.6365)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1 * 0.9889 * N/A % * 0 * N/A
=N/A %

Note: The net income data used here is one times the annual (Dec. 2025) net income data. The Revenue data used here is one times the annual (Dec. 2025) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Latigo Biotherapeutics ROE % Related Terms


Latigo Biotherapeutics ROE % Historical Data

* Premium members only.

The historical data trend for Latigo Biotherapeutics's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Latigo Biotherapeutics ROE % Chart

Latigo Biotherapeutics Annual Data
Trend Dec24 Dec25
ROE %
0.00 0.00

Latigo Biotherapeutics Semi-Annual Data
Dec24 Dec25
ROE % 0.00 0.00

LTGO vs : ROE % Comparison

For the Biotechnology subindustry, Latigo Biotherapeutics's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Latigo Biotherapeutics ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Latigo Biotherapeutics's ROE % distribution charts can be found below:

* The bar in red indicates where Latigo Biotherapeutics's ROE % falls into.


LTGO
8GF Score
Latigo Biotherapeutics Inc LTGO
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Latigo Biotherapeutics ROE % Calculation

Latigo Biotherapeutics's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-109.167/( (-129.599+-231.674)/ 2 )
=-109.167/-180.6365
=N/A %

Latigo Biotherapeutics's annualized ROE % for the quarter that ended in Dec. 2025 is calculated as

ROE %=Net Income (Q: Dec. 2025 )/( (Total Stockholders Equity (Q: Dec. 2024 )+Total Stockholders Equity (Q: Dec. 2025 ))/ count )
=-109.167/( (-129.599+-231.674)/ 2 )
=-109.167/-180.6365
=N/A %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is one times the annual (Dec. 2025) net income data. ROE % is displayed in the 30-year financial page.

* Note that if the average Total Stockholders Equity is zero or negative, then ROE % would be considered meaningless and hence not be calculated.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of 0.00% mean?
Latigo Biotherapeutics (LTGO) has a ROE % of 0.00% as of Dec. 2025. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Latigo Biotherapeutics and its competitors. According to the industry distribution chart, Latigo Biotherapeutics ranks #999999 out of 1248 companies in the Biotechnology industry.
Is Latigo Biotherapeutics' ROE % too high?
Latigo Biotherapeutics' current ROE % is 0.00%. Based on the distribution chart, Latigo Biotherapeutics ranks #999999 out of 1248 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Latigo Biotherapeutics has a GF Score™ of 8/100, reflecting its overall financial health beyond just this single metric.
How does Latigo Biotherapeutics' ROE % compare to ?
According to the Biotechnology industry distribution chart, Latigo Biotherapeutics ranks #999999 out of 1248 companies for ROE %. This places Latigo Biotherapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Latigo Biotherapeutics and its competitors. Latigo Biotherapeutics's current ROE % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Latigo Biotherapeutics stock overvalued right now?
Latigo Biotherapeutics (LTGO) has a current ROE % of 0.00%. The current ROE % is 0.00%. Latigo Biotherapeutics' overall GF Score™ is 8/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Latigo Biotherapeutics (LTGO), the current ROE % is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Latigo Biotherapeutics Business Description

Comparable Companies
Address 1300 Rancho Conejo Boulevard, Suite 305, Thousand Oaks, CA, USA, 91320
Latigo Biotherapeutics Inc is a clinical-stage biotechnology company focused on developing non-opioid pain medicines designed to rapidly and effectively stop the transmission of pain without the risk of addiction. Its flagship product candidates, LTG-001 and LTG-321, are oral Nav1.8 inhibitors being developed for the treatment of acute pain. The company is also developing additional Nav1.8 inhibitor candidates using alternative formulations and delivery approaches.
8GF Score

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ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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