TOVX (Theriva Biologics) ROE %: -53.12% (As of Mar. 2026)


TOVX Theriva Biologics Inc TOVX
28 GF Score
Price $0.24
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What is Theriva Biologics ROE %?

Theriva Biologics TOVX +0.59% 28 ROE % is -53.12% as of Mar. 2026. GuruFocus rates TOVX with a GF Score™ of 28/100. The stock has 3 warning signs investors should review. Among 1,256 Biotechnology companies, Theriva Biologics ranks worse than 85.19% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Theriva Biologics's annualized net income for the quarter that ended in Mar. 2026 was $-8.18 Mil. Theriva Biologics's average Total Stockholders Equity over the quarter that ended in Mar. 2026 was $15.39 Mil. Therefore, Theriva Biologics's annualized ROE % for the quarter that ended in Mar. 2026 was -53.12%.

The historical rank and industry rank for Theriva Biologics's ROE % or its related term are showing as below:

TOVX' s ROE % Range Over the Past 10 Years
Min: -273.97   Med: -78.65   Max: -32.82
Current: -168.6

During the past 13 years, Theriva Biologics's highest ROE % was -32.82%. The lowest was -273.97%. And the median was -78.65%.

TOVX's ROE % is ranked worse than
85.19% of 1256 companies
in the Biotechnology industry
Industry Median: -38.26 vs TOVX: -168.60

Theriva Biologics  (AMEX:TOVX) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-8.176/15.391
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-8.176 / 1.2)*(1.2 / 38.2435)*(38.2435 / 15.391)
=Net Margin %*Asset Turnover*Equity Multiplier
=-681.33 %*0.0314*2.4848
=ROA %*Equity Multiplier
=-21.39 %*2.4848
=-53.12 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-8.176/15.391
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-8.176 / -8.176) * (-8.176 / -8.508) * (-8.508 / 1.2) * (1.2 / 38.2435) * (38.2435 / 15.391)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1 * 0.961 * -709 % * 0.0314 * 2.4848
=-53.12 %

Note: The net income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Theriva Biologics ROE % Related Terms


Theriva Biologics ROE % Historical Data

* Premium members only.

The historical data trend for Theriva Biologics's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Theriva Biologics ROE % Chart

Theriva Biologics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -38.85 -32.82 -38.93 -87.31 -137.82

Theriva Biologics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -100.08 -399.94 -200.96 -72.18 -53.12

TOVX vs CALC, PHIO, PHGE: ROE % Comparison

For the Biotechnology subindustry, Theriva Biologics's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Theriva Biologics ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Theriva Biologics's ROE % distribution charts can be found below:

* The bar in red indicates where Theriva Biologics's ROE % falls into.


TOVX
28GF Score
Theriva Biologics Inc TOVX
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Theriva Biologics ROE % Calculation

Theriva Biologics's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-23.739/( (19.067+15.383)/ 2 )
=-23.739/17.225
=-137.82 %

Theriva Biologics's annualized ROE % for the quarter that ended in Mar. 2026 is calculated as

ROE %=Net Income (Q: Mar. 2026 )/( (Total Stockholders Equity (Q: Dec. 2025 )+Total Stockholders Equity (Q: Mar. 2026 ))/ count )
=-8.176/( (15.383+15.399)/ 2 )
=-8.176/15.391
=-53.12 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -53.12% mean?
Theriva Biologics (TOVX) has a ROE % of -53.12% as of Mar. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Theriva Biologics and its competitors. According to the industry distribution chart, Theriva Biologics ranks #1070 out of 1256 companies in the Biotechnology industry, placing it in the top 85.2%.
Is Theriva Biologics' ROE % too high?
Theriva Biologics' current ROE % is -53.12%. Based on the distribution chart, Theriva Biologics ranks #1070 out of 1256 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Theriva Biologics has a GF Score™ of 28/100, reflecting its overall financial health beyond just this single metric.
How does Theriva Biologics' ROE % compare to CALC and PHIO?
According to the Biotechnology industry distribution chart, Theriva Biologics ranks #1070 out of 1256 companies for ROE %. This places Theriva Biologics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Theriva Biologics and its competitors. Theriva Biologics's current ROE % is -53.12%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Theriva Biologics stock overvalued right now?
Theriva Biologics (TOVX) has a current ROE % of -53.12%. The current ROE % is -53.12%. Theriva Biologics' overall GF Score™ is 28/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Theriva Biologics (TOVX), the current ROE % is -53.12% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Theriva Biologics Business Description

Address 9605 Medical Center Drive, Suite 270, Rockville, MD, USA, 20850
Theriva Biologics Inc is a clinical-stage pharmaceutical company developing a novel oncolytic adenovirus (OV) platform to address devastating cancers with high unmet needs. It is a clinical-stage program VCN-01, designed to break down the tumor stroma, and its preclinical-stage program VCN-11 leverages its proprietary Albumin Shield Technology to protect systemically administered oncolytic viruses from the host immune system. Product Candidates includes SYN-004 (ribaxamase) and SYN-020.
28GF Score

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