WGS (GeneDx Holdings) ROE %: -28.48% (As of Jun. 2026)

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WGS GeneDx Holdings Corp WGS
65 GF Score
Price $90.32
GF Value $73.77
Valuation Modestly Overvalued
! 1 Warning Sign
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What is GeneDx Holdings ROE %?

GeneDx Holdings WGS +3.30% 65 ROE % is -28.48% as of Jun. 2026. GuruFocus rates WGS with a GF Score™ of 65/100 and a GF Value™ of $73.77 (Modestly Overvalued). The stock has 1 warning sign investors should review. Among 197 Medical Diagnostics & Research companies, GeneDx Holdings ranks worse than 78.68% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. GeneDx Holdings's annualized net income for the quarter that ended in Jun. 2026 was $-71.0 Mil. GeneDx Holdings's average Total Stockholders Equity over the quarter that ended in Jun. 2026 was $249.2 Mil. Therefore, GeneDx Holdings's annualized ROE % for the quarter that ended in Jun. 2026 was -28.48%.

The historical rank and industry rank for GeneDx Holdings's ROE % or its related term are showing as below:

WGS' s ROE % Range Over the Past 10 Years
Min: -845.41   Med: -72.97   Max: -7.6
Current: -38.65

During the past 7 years, GeneDx Holdings's highest ROE % was -7.60%. The lowest was -845.41%. And the median was -72.97%.

WGS's ROE % is ranked worse than
78.68% of 197 companies
in the Medical Diagnostics & Research industry
Industry Median: -1.07 vs WGS: -38.65

GeneDx Holdings  (NAS:WGS) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Jun. 2026 )
=Net Income/Total Stockholders Equity
=-70.96/249.1725
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-70.96 / 457.76)*(457.76 / 493.8935)*(493.8935 / 249.1725)
=Net Margin %*Asset Turnover*Equity Multiplier
=-15.5 %*0.9268*1.9821
=ROA %*Equity Multiplier
=-14.37 %*1.9821
=-28.48 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Jun. 2026 )
=Net Income/Total Stockholders Equity
=-70.96/249.1725
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-70.96 / -73.032) * (-73.032 / -60.972) * (-60.972 / 457.76) * (457.76 / 493.8935) * (493.8935 / 249.1725)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 0.9716 * 1.1978 * -13.32 % * 0.9268 * 1.9821
=-28.48 %

Note: The net income data used here is four times the quarterly (Jun. 2026) net income data. The Revenue data used here is four times the quarterly (Jun. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


GeneDx Holdings ROE % Related Terms


GeneDx Holdings ROE % Historical Data

* Premium members only.

The historical data trend for GeneDx Holdings's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

GeneDx Holdings ROE % Chart

GeneDx Holdings Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial -845.41 -171.07 -72.97 -22.10 -7.60

GeneDx Holdings Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 16.18 -10.73 -23.54 -90.08 -28.48

WGS vs NEO, CDNA, PSNL: ROE % Comparison

For the Diagnostics & Research subindustry, GeneDx Holdings's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


GeneDx Holdings ROE % vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, GeneDx Holdings's ROE % distribution charts can be found below:

* The bar in red indicates where GeneDx Holdings's ROE % falls into.


WGS
65GF Score
GeneDx Holdings Corp WGS
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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GeneDx Holdings ROE % Calculation

GeneDx Holdings's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-21.021/( (245.247+308.182)/ 2 )
=-21.021/276.7145
=-7.60 %

GeneDx Holdings's annualized ROE % for the quarter that ended in Jun. 2026 is calculated as

ROE %=Net Income (Q: Jun. 2026 )/( (Total Stockholders Equity (Q: Mar. 2026 )+Total Stockholders Equity (Q: Jun. 2026 ))/ count )
=-70.96/( (254.124+244.221)/ 2 )
=-70.96/249.1725
=-28.48 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Jun. 2026) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -28.48% mean?
GeneDx Holdings (WGS) has a ROE % of -28.48% as of Jun. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on GeneDx Holdings and its competitors. According to the industry distribution chart, GeneDx Holdings ranks #155 out of 197 companies in the Medical Diagnostics & Research industry, placing it in the top 78.7%.
Is GeneDx Holdings' ROE % too high?
GeneDx Holdings' current ROE % is -28.48%. Based on the distribution chart, GeneDx Holdings ranks #155 out of 197 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, GeneDx Holdings has a GF Score™ of 65/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does GeneDx Holdings' ROE % compare to NEO and CDNA?
According to the Medical Diagnostics & Research industry distribution chart, GeneDx Holdings ranks #155 out of 197 companies for ROE %. This places GeneDx Holdings in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Medical Diagnostics & Research company?
A good ROE % depends on the Medical Diagnostics & Research industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on GeneDx Holdings and its competitors. GeneDx Holdings's current ROE % is -28.48%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is GeneDx Holdings stock overvalued right now?
Based on GuruFocus' analysis, GeneDx Holdings (WGS) is currently considered Modestly Overvalued. The stock's GF Value™ is $73.77, compared to a current price of $90.32 — trading 22.4% above its estimated fair value. The current ROE % is -28.48%. GeneDx Holdings' overall GF Score™ is 65/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For GeneDx Holdings (WGS), the current ROE % is -28.48% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is GeneDx Holdings (WGS) Overvalued in 2026?

Based on GuruFocus' analysis, GeneDx Holdings stock appears to be overvalued. The current stock price of $90.32 is trading 22.4% above its estimated GF Value™ of $73.77. GuruFocus considers GeneDx Holdings to be Modestly Overvalued.

Key valuation signals for WGS:

  • ROE %: -28.48%
  • GF Value™: $73.77 vs. price of $90.32 (22.4% above fair value)
  • GF Score™: 65/100 with 1 warning sign

No single metric tells the full story. See the WGS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


GeneDx Holdings Business Description

Address 333 Ludlow Street, North Tower, 6th Floor, Stamford, CT, USA, 06902
GeneDx Holdings Corp focuses on genomics, creating the foundation for providing genomic information at scale and pioneering exome and genome sequencing for rare and ultra-rare genetic pediatric disorders. The company believes exome and genome testing will become the standard for diagnosing genetic disease, with the potential to transform healthcare from reactive to proactive. It aims to advance precision medicine by offering genetic diagnoses at the earliest moments, driving improved outcomes, and fueling discovery with genomic intelligence. Its operating segment mainly provides pediatric and rare disease diagnostics, focusing on whole exome and genome sequencing and, to a lesser extent, data and information services.
65GF Score

Get the complete analysis for WGS

ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$90.32
Price
$73.77
GF Value