Heidelberg Pharma AG (XTER:HPHA) ROE %: Negative Equity% (As of May. 2026)

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XTER:HPHA Heidelberg Pharma AG XTER:HPHA
32 GF Score
Price €2.55
GF Value €2.87
Valuation Significantly Overvalued
! 5 Warning Signs
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What is Heidelberg Pharma AG ROE %?

Heidelberg Pharma AG XTER:HPHA -1.92% 32 ROE % is Negative Equity% as of May. 2026. GuruFocus rates XTER:HPHA with a GF Score™ of 32/100 and a GF Value™ of €2.87 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 1,250 Biotechnology companies, Heidelberg Pharma AG ranks worse than 96.72% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Heidelberg Pharma AG's annualized net income for the quarter that ended in May. 2026 was €3.45 Mil. Heidelberg Pharma AG's average Total Stockholders Equity over the quarter that ended in May. 2026 was €-14.69 Mil. Therefore, Heidelberg Pharma AG's annualized ROE % for the quarter that ended in May. 2026 was Negative Equity%.

The historical rank and industry rank for Heidelberg Pharma AG's ROE % or its related term are showing as below:

XTER:HPHA' s ROE % Range Over the Past 10 Years
Min: -724.36   Med: -51.03   Max: -35.08
Current: -724.36

During the past 13 years, Heidelberg Pharma AG's highest ROE % was -35.08%. The lowest was -724.36%. And the median was -51.03%.

XTER:HPHA's ROE % is ranked worse than
96.72% of 1250 companies
in the Biotechnology industry
Industry Median: -38.53 vs XTER:HPHA: -724.36

Heidelberg Pharma AG  (XTER:HPHA) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: May. 2026 )
=Net Income/Total Stockholders Equity
=3.452/-14.6875
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(3.452 / 17.38)*(17.38 / 38.8365)*(38.8365 / -14.6875)
=Net Margin %*Asset Turnover*Equity Multiplier
=19.86 %*0.4475*N/A
=ROA %*Equity Multiplier
=8.89 %*N/A
=Negative Equity %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: May. 2026 )
=Net Income/Total Stockholders Equity
=3.452/-14.6875
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (3.452 / 5.152) * (5.152 / 1.776) * (1.776 / 17.38) * (17.38 / 38.8365) * (38.8365 / -14.6875)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 0.67 * 2.9009 * 10.22 % * 0.4475 * N/A
=Negative Equity %

Note: The net income data used here is four times the quarterly (May. 2026) net income data. The Revenue data used here is four times the quarterly (May. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Heidelberg Pharma AG ROE % Related Terms


Heidelberg Pharma AG ROE % Historical Data

* Premium members only.

The historical data trend for Heidelberg Pharma AG's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Heidelberg Pharma AG ROE % Chart

Heidelberg Pharma AG Annual Data
Trend Nov16 Nov17 Nov18 Nov19 Nov20 Nov21 Nov22 Nov23 Nov24 Nov25
ROE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -267.02 -53.73 -35.08 -48.33 -423.91

Heidelberg Pharma AG Quarterly Data
Aug21 Nov21 Feb22 May22 Aug22 Nov22 Feb23 May23 Aug23 Nov23 Feb24 May24 Aug24 Nov24 Feb25 May25 Aug25 Nov25 Feb26 May26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -122.14 -233.07 0.00 0.00 Negative Equity

XTER:HPHA vs VRTX, REGN, ALNY: ROE % Comparison

For the Biotechnology subindustry, Heidelberg Pharma AG's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Heidelberg Pharma AG ROE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Heidelberg Pharma AG's ROE % distribution charts can be found below:

* The bar in red indicates where Heidelberg Pharma AG's ROE % falls into.


XTER:HPHA
32GF Score
Heidelberg Pharma AG XTER:HPHA
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Heidelberg Pharma AG ROE % Calculation

Heidelberg Pharma AG's annualized ROE % for the fiscal year that ended in Nov. 2025 is calculated as

ROE %=Net Income (A: Nov. 2025 )/( (Total Stockholders Equity (A: Nov. 2024 )+Total Stockholders Equity (A: Nov. 2025 ))/ count )
=-42.281/( (30.866+-10.918)/ 2 )
=-42.281/9.974
=-423.91 %

Heidelberg Pharma AG's annualized ROE % for the quarter that ended in May. 2026 is calculated as

ROE %=Net Income (Q: May. 2026 )/( (Total Stockholders Equity (Q: Feb. 2026 )+Total Stockholders Equity (Q: May. 2026 ))/ count )
=3.452/( (-15.156+-14.219)/ 2 )
=3.452/-14.6875
=Negative Equity %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (May. 2026) net income data. ROE % is displayed in the 30-year financial page.

* Note that if the average Total Stockholders Equity is zero or negative, then ROE % would be considered meaningless and hence not be calculated.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of Negative Equity% mean?
Heidelberg Pharma AG (XTER:HPHA) has a ROE % of Negative Equity% as of May. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Heidelberg Pharma AG and its competitors. According to the industry distribution chart, Heidelberg Pharma AG ranks #1209 out of 1250 companies in the Biotechnology industry, placing it in the top 96.7%.
Is Heidelberg Pharma AG's ROE % too high?
Heidelberg Pharma AG's current ROE % is Negative Equity%. Based on the distribution chart, Heidelberg Pharma AG ranks #1209 out of 1250 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Heidelberg Pharma AG has a GF Score™ of 32/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Heidelberg Pharma AG's ROE % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Heidelberg Pharma AG ranks #1209 out of 1250 companies for ROE %. This places Heidelberg Pharma AG in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Biotechnology company?
A good ROE % depends on the Biotechnology industry context. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Heidelberg Pharma AG and its competitors. Heidelberg Pharma AG's current ROE % is Negative Equity%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Heidelberg Pharma AG stock overvalued right now?
Based on GuruFocus' analysis, Heidelberg Pharma AG (XTER:HPHA) is currently considered Significantly Overvalued. The stock's GF Value™ is €2.87, compared to a current price of €2.55 — trading 11.1% below its estimated fair value. The current ROE % is Negative Equity%. Heidelberg Pharma AG's overall GF Score™ is 32/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Heidelberg Pharma AG (XTER:HPHA), the current ROE % is Negative Equity% as of May. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Heidelberg Pharma AG (XTER:HPHA) Overvalued in 2026?

Based on GuruFocus' analysis, Heidelberg Pharma AG stock appears to be undervalued. The current stock price of €2.55 is trading 11.1% below its estimated GF Value™ of €2.87. GuruFocus considers Heidelberg Pharma AG to be Significantly Overvalued.

Key valuation signals for XTER:HPHA:

  • ROE %: Negative Equity%
  • GF Value™: €2.87 vs. price of €2.55 (11.1% below fair value)
  • GF Score™: 32/100 with 5 warning signs

No single metric tells the full story. See the XTER:HPHA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Heidelberg Pharma AG Business Description

Other Exchanges 0QW5:UKHPHA:Austria
Address Gregor-Mendel-Street 22, Ladenburg, DEU, 68526
Heidelberg Pharma AG is a biopharmaceutical company developing oncology treatments through antibody drug conjugates (ADCs), which combine antibody specificity with toxin potency to selectively target and kill cancer cells. The Company researches, develops, and produces these ADCs, and has built an ADC toolbox using various antibodies and payloads to address multiple cancers and overcome tumor resistance. Its activities focus on its proprietary ATAC technology based on Amanitin, the toxin of the death cap mushroom, leveraging its biological mechanism as a novel cancer therapy. The ATAC platform is used to develop proprietary ADC candidates and is also applied in collaborations with third parties.
32GF Score

Get the complete analysis for XTER:HPHA

ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€2.55
Price
€2.87
GF Value