AZTR (Azitra) ROIC %: -733.44% (As of Mar. 2026)


AZTR Azitra Inc AZTR
35 GF Score
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What is Azitra ROIC %?

Azitra AZTR +0.78% 35 ROIC % is -733.44% as of Mar. 2026. GuruFocus rates AZTR with a GF Score™ of 35/100. The stock has 1 warning sign investors should review.

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. Azitra's annualized return on invested capital (ROIC %) for the quarter that ended in Mar. 2026 was -733.44%.

As of today (2026-06-29), Azitra's WACC % is -2.94%. Azitra's ROIC % is -495.47% (calculated using TTM income statement data). Azitra earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Azitra  (AMEX:AZTR) ROIC % Explanation

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROIC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Azitra's WACC % is -2.94%. Azitra's ROIC % is -495.47% (calculated using TTM income statement data). Azitra earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROIC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Azitra ROIC % Related Terms


Azitra ROIC % Historical Data

* Premium members only.

The historical data trend for Azitra's ROIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Azitra ROIC % Chart

Azitra Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
ROIC %
-520.67 -358.65 -231.65 -409.35 -443.65

Azitra Quarterly Data
Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -517.85 -469.50 -420.75 -340.39 -733.44

AZTR vs CASIF, ITRMF, OGEN: ROIC % Comparison

For the Biotechnology subindustry, Azitra's ROIC %, along with its competitors' market caps and ROIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Azitra ROIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Azitra's ROIC % distribution charts can be found below:

* The bar in red indicates where Azitra's ROIC % falls into.


AZTR
35GF Score
Azitra Inc AZTR
ROIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Azitra ROIC % Calculation

Azitra's annualized Return on Invested Capital (ROIC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROIC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-10.967 * ( 1 - 0% )/( (2.435 + 2.509)/ 2 )
=-10.967/2.472
=-443.65 %

where

Azitra's annualized Return on Invested Capital (ROIC %) for the quarter that ended in Mar. 2026 is calculated as:

ROIC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=-15.736 * ( 1 - 0% )/( (2.509 + 1.782)/ 2 )
=-15.736/2.1455
=-733.44 %

where

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROIC % →
What does a ROIC % of -733.44% mean?
Azitra (AZTR) has a ROIC % of -733.44% as of Mar. 2026. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Azitra and its competitors.
Is Azitra's ROIC % too high?
Azitra's current ROIC % is -733.44%. Overall, Azitra has a GF Score™ of 35/100, reflecting its overall financial health beyond just this single metric.
How does Azitra's ROIC % compare to CASIF and ITRMF?
Azitra's ROIC % of -733.44% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROIC % for a Biotechnology company?
A good ROIC % depends on the Biotechnology industry context. However, ROIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROIC % mean?
A high ROIC % can signal that a stock is expensive relative to its fundamentals. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Azitra and its competitors. Azitra's current ROIC % is -733.44%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Azitra stock overvalued right now?
Azitra (AZTR) has a current ROIC % of -733.44%. The current ROIC % is -733.44%. Azitra's overall GF Score™ is 35/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROIC % calculated?
ROIC % is calculated from a company's financial statements. For Azitra (AZTR), the current ROIC % is -733.44% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Azitra Business Description

Address 21 Business Park Drive, Branford, CT, USA, 06405
Azitra Inc is an early-stage clinical biopharmaceutical company focused on developing therapies for precision dermatology using engineered proteins and live biotherapeutic products. Its discovery platform is screened for naturally occurring bacterial cells with beneficial effects. These microbes are then genomically sequenced and engineered to make cellular therapies, recombinant therapeutic proteins, peptides, and small molecules for the precision treatment of dermatology diseases. The company's product candidates include ATR-12, for treating the orphan disease and Netherton syndrome; ATR-04, a genetically modified strain of S. epidermidis for treating the papulopustular rash; and ATR-01, a potential treatment for ichthyosis vulgaris, a chronic, abnormally dry, scaly skin disease.
35GF Score

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ROIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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