OBX (Obsidian Therapeutics) ROIC %: -590.95% (As of Dec. 2025)

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OBX Obsidian Therapeutics Inc OBX
8 GF Score
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What is Obsidian Therapeutics ROIC %?

Obsidian Therapeutics OBX -1.79% 8 ROIC % is -590.95% as of Dec. 2025. GuruFocus rates OBX with a GF Score™ of 8/100.

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. Obsidian Therapeutics's annualized return on invested capital (ROIC %) for the quarter that ended in Dec. 2025 was -590.95%.

As of today (2026-08-07), Obsidian Therapeutics's WACC % is 0.00%. Obsidian Therapeutics's ROIC % is 0.00% (calculated using TTM income statement data). Obsidian Therapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Obsidian Therapeutics  (NAS:OBX) ROIC % Explanation

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROIC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Obsidian Therapeutics's WACC % is 0.00%. Obsidian Therapeutics's ROIC % is 0.00% (calculated using TTM income statement data). Obsidian Therapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROIC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Obsidian Therapeutics ROIC % Related Terms


Obsidian Therapeutics ROIC % Historical Data

* Premium members only.

The historical data trend for Obsidian Therapeutics's ROIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Obsidian Therapeutics ROIC % Chart

Obsidian Therapeutics Annual Data
Trend Dec24 Dec25
ROIC %
-447.46 -590.95

Obsidian Therapeutics Semi-Annual Data
Dec24 Dec25
ROIC % -447.46 -590.95

OBX vs : ROIC % Comparison

For the Biotechnology subindustry, Obsidian Therapeutics's ROIC %, along with its competitors' market caps and ROIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Obsidian Therapeutics ROIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Obsidian Therapeutics's ROIC % distribution charts can be found below:

* The bar in red indicates where Obsidian Therapeutics's ROIC % falls into.


OBX
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Obsidian Therapeutics Inc OBX
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Obsidian Therapeutics ROIC % Calculation

Obsidian Therapeutics's annualized Return on Invested Capital (ROIC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROIC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-105.667 * ( 1 - 0% )/( (20.394 + 15.368)/ 2 )
=-105.667/17.881
=-590.95 %

where

Obsidian Therapeutics's annualized Return on Invested Capital (ROIC %) for the quarter that ended in Dec. 2025 is calculated as:

ROIC % (Q: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2024 ) + Invested Capital (Q: Dec. 2025 ))/ count )
=-105.667 * ( 1 - 0% )/( (20.394 + 15.368)/ 2 )
=-105.667/17.881
=-590.95 %

where

Note: The Operating Income data used here is one times the annual (Dec. 2025) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROIC % →
What does a ROIC % of -590.95% mean?
Obsidian Therapeutics (OBX) has a ROIC % of -590.95% as of Dec. 2025. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Obsidian Therapeutics and its competitors.
Is Obsidian Therapeutics' ROIC % too high?
Obsidian Therapeutics' current ROIC % is -590.95%. Overall, Obsidian Therapeutics has a GF Score™ of 8/100, reflecting its overall financial health beyond just this single metric.
How does Obsidian Therapeutics' ROIC % compare to ?
Obsidian Therapeutics' ROIC % of -590.95% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROIC % for a Biotechnology company?
A good ROIC % depends on the Biotechnology industry context. However, ROIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROIC % mean?
A high ROIC % can signal that a stock is expensive relative to its fundamentals. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Obsidian Therapeutics and its competitors. Obsidian Therapeutics's current ROIC % is -590.95%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Obsidian Therapeutics stock overvalued right now?
Obsidian Therapeutics (OBX) has a current ROIC % of -590.95%. The current ROIC % is -590.95%. Obsidian Therapeutics' overall GF Score™ is 8/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROIC % calculated?
ROIC % is calculated from a company's financial statements. For Obsidian Therapeutics (OBX), the current ROIC % is -590.95% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Obsidian Therapeutics Business Description

Comparable Companies
Address 1030 Massachusetts Avenue, Suite 400, Cambridge, MA, USA, 02138
Obsidian Therapeutics Inc is a clinical-stage biopharmaceutical company harnessing novel protein-regulation technology to develop engineered tumor infiltrating lymphocytes (TIL) cell therapies for the treatment of patients with solid tumors. The company's proprietary cytoDRiVE platform is versatile and allows it to leverage drug responsive domains to control protein function, with its initial focus on TIL cell therapies developed from this platform (cytoTILs). The company's flagship product candidate, OBX-115, is a novel, genetically engineered, autologous TIL cell therapy currently in a Phase 2 clinical trial for the treatment of melanoma and a Phase 1 clinical trial for the treatment of non-small cell lung cancer.
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