NRIX (Nurix Therapeutics) 10-Year ROIIC % : -117.14% (As of Nov. 2025)

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NRIX Nurix Therapeutics Inc NRIX
61 GF Score
Price $25.22
GF Value $6.41
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Nurix Therapeutics 10-Year ROIIC %?

Nurix Therapeutics NRIX +0.36% 61 10-Year ROIIC % is -117.14 as of Nov. 2025. GuruFocus rates NRIX with a GF Score™ of 61/100 and a GF Value™ of $6.41 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 1,104 Biotechnology companies, Nurix Therapeutics ranks worse than 70.2% on this metric.

10-Year Return on Invested Incremental Capital (10-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 10-year. Nurix Therapeutics does not have enough data to calculate 10-Year ROIIC %.


Nurix Therapeutics  (NAS:NRIX) 10-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Nurix Therapeutics 10-Year ROIIC % Related Terms


Nurix Therapeutics 10-Year ROIIC % Historical Data

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The historical data trend for Nurix Therapeutics's 10-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Nurix Therapeutics 10-Year ROIIC % Chart

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NRIX vs PHVS, NKTR, TRVI: 10-Year ROIIC % Comparison

For the Biotechnology subindustry, Nurix Therapeutics's 10-Year ROIIC %, along with its competitors' market caps and 10-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Nurix Therapeutics 10-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Nurix Therapeutics's 10-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Nurix Therapeutics's 10-Year ROIIC % falls into.


NRIX
61GF Score
Nurix Therapeutics Inc NRIX
10-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Nurix Therapeutics 10-Year ROIIC % Calculation

Nurix Therapeutics's 10-Year ROIIC % for the quarter that ended in Nov. 2025 is calculated as:

10-Year ROIIC %=10-Year Incremental Net Operating Profit After Taxes (NOPAT)**/10-Year Incremental Invested Capital**
=( -285.666 (Nov. 2025) - (Nov. 2015) )/( 125.357 (Nov. 2025) - (Nov. 2015) )
=/
=N/A%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 10-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 10-Year ROIIC % →
What does a 10-Year ROIIC % of -117.14 mean?
Nurix Therapeutics (NRIX) has a 10-Year ROIIC % of -117.14 as of Nov. 2025. 10-Year ROIIC % measures the change in earnings as a percentage of change in investment over 10-year. View historical data on Nurix Therapeutics and its competitors. According to the industry distribution chart, Nurix Therapeutics ranks #775 out of 1104 companies in the Biotechnology industry, placing it in the top 70.2%.
Is Nurix Therapeutics' 10-Year ROIIC % too high?
Nurix Therapeutics' current 10-Year ROIIC % is -117.14. Based on the distribution chart, Nurix Therapeutics ranks #775 out of 1104 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Nurix Therapeutics has a GF Score™ of 61/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Nurix Therapeutics' 10-Year ROIIC % compare to PHVS and NKTR?
According to the Biotechnology industry distribution chart, Nurix Therapeutics ranks #775 out of 1104 companies for 10-Year ROIIC %. This places Nurix Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 10-Year ROIIC % for a Biotechnology company?
A good 10-Year ROIIC % depends on the Biotechnology industry context. However, 10-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 10-Year ROIIC % mean?
A high 10-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 10-Year ROIIC % measures the change in earnings as a percentage of change in investment over 10-year. View historical data on Nurix Therapeutics and its competitors. Nurix Therapeutics's current 10-Year ROIIC % is -117.14. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nurix Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Nurix Therapeutics (NRIX) is currently considered Significantly Overvalued. The stock's GF Value™ is $6.41, compared to a current price of $25.22 — trading 293.4% above its estimated fair value. The current 10-Year ROIIC % is -117.14. Nurix Therapeutics' overall GF Score™ is 61/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 10-Year ROIIC % calculated?
10-Year ROIIC % is calculated from a company's financial statements. For Nurix Therapeutics (NRIX), the current 10-Year ROIIC % is -117.14 as of Nov. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Nurix Therapeutics (NRIX) Overvalued in 2026?

Based on GuruFocus' analysis, Nurix Therapeutics stock appears to be overvalued. The current stock price of $25.22 is trading 293.4% above its estimated GF Value™ of $6.41. GuruFocus considers Nurix Therapeutics to be Significantly Overvalued.

Key valuation signals for NRIX:

  • 10-Year ROIIC %: -117.14
  • GF Value™: $6.41 vs. price of $25.22 (293.4% above fair value)
  • GF Score™: 61/100 with 6 warning signs

No single metric tells the full story. See the NRIX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Nurix Therapeutics Business Description

Address 1600 Sierra Point Parkway, Brisbane, CA, USA, 94005
Nurix Therapeutics Inc is a clinical-stage biopharmaceutical company focused on the discovery, development, and potential commercialization of targeted protein degradation therapies for cancer and inflammatory diseases. It utilizes an integrated discovery platform that incorporates artificial intelligence and ligase expertise to support its research activities. The company's pipeline includes Bexobrutideg (NX-5948), Zelebrudomide (NX-2127), NX-1607 and BRAF degrader. These drug candidates target specific proteins involved in immune and cancer-related pathways. It operates in a single business segment.
61GF Score

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10-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$25.22
Price
$6.41
GF Value