Cabaletta BioCABA +6.69%34 3-Year ROIIC % is -254.75 as of Dec. 2025. GuruFocus rates CABA with a GF Score™ of 34/100. The stock has 1 warning sign investors should review. Among 1,324 Biotechnology companies, Cabaletta Bio ranks worse than 82.25% on this metric.
3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year.
Cabaletta Bio's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was -254.75%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
The industry rank for Cabaletta Bio's 3-Year ROIIC % or its related term are showing as below:
CABA's 3-Year ROIIC % is ranked worse than 82.25% of 1324
companies
in the Biotechnology industry
Industry Median: -4.42
vs CABA: -254.75
Cabaletta Bio (NAS:CABA) 3-Year ROIIC % Explanation
Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.
High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
Be Aware
It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.
Cabaletta Bio 3-Year ROIIC % Related Terms
Cabaletta Bio 3-Year ROIIC % Historical Data
* Premium members only.
The historical data trend for Cabaletta Bio's 3-Year ROIIC % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
CABA vs RZLT, CCCC, OCGN: 3-Year ROIIC % Comparison
For the Biotechnology subindustry, Cabaletta Bio's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Cabaletta Bio 3-Year ROIIC % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Cabaletta Bio's 3-Year ROIIC % distribution charts can be found below:
* The bar in red indicates where Cabaletta Bio's 3-Year ROIIC % falls into.
Cabaletta Bio's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:
3-Year ROIIC %
=
3-Year Incremental Net Operating Profit After Taxes (NOPAT)**
/
3-Year Incremental Invested Capital**
=
( -172.241 (Dec. 2025) - -54.139 (Dec. 2022) )
/
( 60.227 (Dec. 2025) - 13.867 (Dec. 2022) )
=
-118.102
/
46.36
=
-254.75%***
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
Cabaletta Bio (CABA) has a 3-Year ROIIC % of -254.75 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Cabaletta Bio and its competitors. According to the industry distribution chart, Cabaletta Bio ranks #1089 out of 1324 companies in the Biotechnology industry, placing it in the top 82.3%.
Is Cabaletta Bio's 3-Year ROIIC % too high?
Cabaletta Bio's current 3-Year ROIIC % is -254.75. Based on the distribution chart, Cabaletta Bio ranks #1089 out of 1324 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Cabaletta Bio has a GF Score™ of 34/100, reflecting its overall financial health beyond just this single metric.
How does Cabaletta Bio's 3-Year ROIIC % compare to RZLT and CCCC?
According to the Biotechnology industry distribution chart, Cabaletta Bio ranks #1089 out of 1324 companies for 3-Year ROIIC %. This places Cabaletta Bio in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Cabaletta Bio and its competitors. Cabaletta Bio's current 3-Year ROIIC % is -254.75. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cabaletta Bio stock overvalued right now?
Cabaletta Bio (CABA) has a current 3-Year ROIIC % of -254.75. The current 3-Year ROIIC % is -254.75. Cabaletta Bio's overall GF Score™ is 34/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Cabaletta Bio (CABA), the current 3-Year ROIIC % is -254.75 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Cabaletta Bio Inc is a late clinical-stage biotechnology company focused on the discovery and development of engineered T cell therapies for autoimmune diseases. Its proprietary Cabaletta Approach to B cell Ablation (CABA) platform includes the CARTA approach, which uses chimeric antigen receptor T cells to eliminate B cells and potentially reset the immune system. The company develops cellular therapies including CAR T and CAAR T product candidates. Its candidate, rese-cel (resecabtagene autoleucel), a CD19-CAR T cell therapy, is being evaluated in Phase 1/2 trials for autoimmune diseases such as systemic lupus erythematosus, myositis, systemic sclerosis, generalized myasthenia gravis, and pemphigus vulgaris.
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