Knight Therapeutics (FRA:04K) 3-Year ROIIC % : 13.82% (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

FRA:04K Knight Therapeutics Inc FRA:04K
73 GF Score
Price €6.10
GF Value €5.29
! 6 Warning Signs
View Full Analysis

What is Knight Therapeutics 3-Year ROIIC %?

Knight Therapeutics FRA:04K 73 3-Year ROIIC % is 13.82 as of Dec. 2025. GuruFocus rates FRA:04K with a GF Score™ of 73/100 and a GF Value™ of €5.29. The stock has 6 warning signs investors should review. Among 946 Drug Manufacturers companies, Knight Therapeutics ranks better than 64.9% on this metric.

3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year. Knight Therapeutics's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was 13.82%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for Knight Therapeutics's 3-Year ROIIC % or its related term are showing as below:

FRA:04K's 3-Year ROIIC % is ranked better than
64.9% of 946 companies
in the Drug Manufacturers industry
Industry Median: 3.635 vs FRA:04K: 13.82

Knight Therapeutics  (FRA:04K) 3-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Knight Therapeutics 3-Year ROIIC % Related Terms


Knight Therapeutics 3-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for Knight Therapeutics's 3-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Knight Therapeutics 3-Year ROIIC % Chart

Knight Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year ROIIC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -1.93 1.63 30.68 -53.05 13.82

Knight Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 13.82 0.00

FRA:04K vs ZTS, UTHR: 3-Year ROIIC % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Knight Therapeutics's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Knight Therapeutics 3-Year ROIIC % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Knight Therapeutics's 3-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Knight Therapeutics's 3-Year ROIIC % falls into.


FRA:04K
73GF Score
Knight Therapeutics Inc FRA:04K
3-Year ROIIC % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Knight Therapeutics 3-Year ROIIC % Calculation

Knight Therapeutics's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:

3-Year ROIIC %=3-Year Incremental Net Operating Profit After Taxes (NOPAT)**/3-Year Incremental Invested Capital**
=( -1.1667645 (Dec. 2025) - -8.0614 (Dec. 2022) )/( 506.798 (Dec. 2025) - 520.01 (Dec. 2022) )
=6.8946355/-13.212
=-52.18%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 3-Year ROIIC % →
What does a 3-Year ROIIC % of 13.82 mean?
Knight Therapeutics (FRA:04K) has a 3-Year ROIIC % of 13.82 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Knight Therapeutics and its competitors. According to the industry distribution chart, Knight Therapeutics ranks #332 out of 946 companies in the Drug Manufacturers industry, placing it in the top 35.1%.
Is Knight Therapeutics' 3-Year ROIIC % too high?
Knight Therapeutics' current 3-Year ROIIC % is 13.82. The Drug Manufacturers industry median 3-Year ROIIC % is 3.64. Knight Therapeutics' value of 13.82 is 280.2% above this industry median. Based on the distribution chart, Knight Therapeutics ranks #332 out of 946 companies in the Drug Manufacturers industry, which is above the industry midpoint. Overall, Knight Therapeutics has a GF Score™ of 73/100, reflecting its overall financial health beyond just this single metric.
How does Knight Therapeutics' 3-Year ROIIC % compare to ZTS and UTHR?
According to the Drug Manufacturers industry distribution chart, Knight Therapeutics ranks #332 out of 946 companies for 3-Year ROIIC %. This puts Knight Therapeutics in the upper half of its industry. The industry median 3-Year ROIIC % is 3.64. Knight Therapeutics' value of 13.82 is 280.2% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Drug Manufacturers company?
The median 3-Year ROIIC % among Drug Manufacturers companies is 3.64, based on 946 companies in the industry. Companies in the top quartile (top 25%) have a 3-Year ROIIC % significantly above this median, while those in the bottom quartile fall well below. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Knight Therapeutics's current 3-Year ROIIC % of 13.82 is 280.2% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Knight Therapeutics and its competitors. For the Drug Manufacturers industry, the median 3-Year ROIIC % is 3.64 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Knight Therapeutics's current 3-Year ROIIC % is 13.82. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Knight Therapeutics stock overvalued right now?
Knight Therapeutics (FRA:04K) has a current 3-Year ROIIC % of 13.82. The stock's GF Value™ is €5.29, compared to a current price of €6.10 — trading 15.3% above its estimated fair value. The current 3-Year ROIIC % is 13.82 and 280.2% above the Drug Manufacturers industry median of 3.64. Knight Therapeutics' overall GF Score™ is 73/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Knight Therapeutics (FRA:04K), the current 3-Year ROIIC % is 13.82 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Knight Therapeutics (FRA:04K) Overvalued in 2026?

Based on GuruFocus' analysis, Knight Therapeutics stock appears to be overvalued. The current stock price of €6.10 is trading 15.3% above its estimated GF Value™ of €5.29.

Key valuation signals for FRA:04K:

  • 3-Year ROIIC %: 13.82
  • GF Value™: €5.29 vs. price of €6.10 (15.3% above fair value)
  • GF Score™: 73/100 with 6 warning signs
  • Industry Position: 280.2% above the Drug Manufacturers median (#332 of 946)

No single metric tells the full story. See the FRA:04K stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Knight Therapeutics Business Description

Other Exchanges KHTRF:USAGUD:Canada
Address 100 Alexis Nihon Boulevard, Suite 600, Saint-Laurent, QC, CAN, H4M 2P2
Knight Therapeutics Inc is a specialty and generic drug manufacturing company. The company's principal business activity is focused on developing, acquiring, in-licensing, out-licensing, marketing, and commercializing pharmaceuticalproducts. and distributing pharmaceutical products, consumer health products, and medical devices in Canada, Latin America and select international markets. The company finances other life sciences companies across the globe in order to generate interest income, strengthen relationships in the life sciences industry, and to secure product distribution rights. Geographically, the company generates revenue from Brazil, Canada, Colombia, Argentina, Mexico, Rest of LATAM, and Others, with the majority revenue generated from the Brazil region.
73GF Score

Get the complete analysis for FRA:04K

3-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€6.10
Price
€5.29
GF Value