Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
MDxHealthMDXH -4.64%49 3-Year ROIIC % is 72.49 as of Dec. 2025, which is 758% above its 10-year median of 8.45. GuruFocus rates MDXH with a GF Score™ of 49/100 and a GF Value™ of $2.20 (Possible Value Trap). The stock has 5 warning signs investors should review. Among 204 Medical Diagnostics & Research companies, MDxHealth ranks better than 78.92% on this metric.
3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year.
MDxHealth's 3-Year ROIIC % for the quarter that ended in Dec. 2025 was 72.49%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
The industry rank for MDxHealth's 3-Year ROIIC % or its related term are showing as below:
MDXH's 3-Year ROIIC % is ranked better than 78.92% of 204
companies
in the Medical Diagnostics & Research industry
Industry Median: 0.125
vs MDXH: 72.49
MDxHealth (NAS:MDXH) 3-Year ROIIC % Explanation
Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.
High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.
Be Aware
It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.
MDxHealth 3-Year ROIIC % Related Terms
MDxHealth 3-Year ROIIC % Historical Data
* Premium members only.
The historical data trend for MDxHealth's 3-Year ROIIC % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
MDXH vs AWHL, BIOQ, XWEL: 3-Year ROIIC % Comparison
For the Diagnostics & Research subindustry, MDxHealth's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
MDxHealth 3-Year ROIIC % vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, MDxHealth's 3-Year ROIIC % distribution charts can be found below:
* The bar in red indicates where MDxHealth's 3-Year ROIIC % falls into.
MDxHealth's 3-Year ROIIC % for the quarter that ended in Dec. 2025 is calculated as:
3-Year ROIIC %
=
3-Year Incremental Net Operating Profit After Taxes (NOPAT)**
/
3-Year Incremental Invested Capital**
=
( -14.563075 (Dec. 2025) - -38.415 (Dec. 2022) )
/
( 127.007 (Dec. 2025) - 94.101 (Dec. 2022) )
=
23.851925
/
32.906
=
72.49%***
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
MDxHealth (MDXH) has a 3-Year ROIIC % of 72.49 as of Dec. 2025. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on MDxHealth and its competitors. This is 758% above median its historical median of 8.45. According to the industry distribution chart, MDxHealth ranks #43 out of 204 companies in the Medical Diagnostics & Research industry, placing it in the top 21.1%.
Is MDxHealth's 3-Year ROIIC % too high?
MDxHealth's current 3-Year ROIIC % of 72.49 is 758% above median its 10-year median of 8.45. The Medical Diagnostics & Research industry median 3-Year ROIIC % is 0.13. MDxHealth's value of 72.49 is 57892% above this industry median. Based on the distribution chart, MDxHealth ranks #43 out of 204 companies in the Medical Diagnostics & Research industry, which is in the top quartile — a strong position relative to peers. Overall, MDxHealth has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does MDxHealth's 3-Year ROIIC % compare to AWHL and BIOQ?
According to the Medical Diagnostics & Research industry distribution chart, MDxHealth ranks #43 out of 204 companies for 3-Year ROIIC %. This places MDxHealth in the top 21% of its industry — outperforming the majority of peers. The industry median 3-Year ROIIC % is 0.13. MDxHealth's value of 72.49 is 57892% above this benchmark. While the company's 10-year median is 8.45 vs. the industry median of 0.13, MDxHealth has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Medical Diagnostics & Research company?
The median 3-Year ROIIC % among Medical Diagnostics & Research companies is 0.13, based on 204 companies in the industry. Companies in the top quartile (top 25%) have a 3-Year ROIIC % significantly above this median, while those in the bottom quartile fall well below. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. MDxHealth's current 3-Year ROIIC % of 72.49 is 57892% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on MDxHealth and its competitors. For the Medical Diagnostics & Research industry, the median 3-Year ROIIC % is 0.13 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. MDxHealth's current 3-Year ROIIC % is 72.49, which is 758% above median its own 10-year median of 8.45. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is MDxHealth stock overvalued right now?
Based on GuruFocus' analysis, MDxHealth (MDXH) is currently considered Possible Value Trap. The stock's GF Value™ is $2.20, compared to a current price of $0.43 — trading 80.7% below its estimated fair value. The current 3-Year ROIIC % is 72.49, which is 758% above median its 10-year median of 8.45 and 57892% above the Medical Diagnostics & Research industry median of 0.13. MDxHealth's overall GF Score™ is 49/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For MDxHealth (MDXH), the current 3-Year ROIIC % is 72.49 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is MDxHealth (MDXH) Overvalued in 2026?
Based on GuruFocus' analysis, MDxHealth stock appears to be undervalued.
The current stock price of $0.43 is trading 80.7% below its estimated GF Value™ of $2.20.
GuruFocus considers MDxHealth to be Possible Value Trap.
Key valuation signals for MDXH:
3-Year ROIIC %: 72.49 (758% above median its 10-year median of 8.45)
GF Value™: $2.20 vs. price of $0.43 (80.7% below fair value)
Industry Position: 57892% above the Medical Diagnostics & Research median (#43 of 204)
No single metric tells the full story. See the MDXH stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
MDxHealth SA is a multinational healthcare company that provides actionable molecular diagnostic information to personalize the diagnosis and treatment of cancer. Its tests are based on proprietary genomic, epigenetic, and other molecular technologies and assist physicians with the diagnosis of urologic cancers, the prognosis of recurrence risk, and the prediction of response to a specific therapy. It derives revenues from clinical laboratory service testing or the out-licensing of the company's patented DNA methylation platform and biomarkers. Geographically, it derives revenue from the United States of America (USA) and Europe.
49GF Score
Get the complete analysis for MDXH
3-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
MDXH has been successfully added to your 
