AGIO (Agios Pharmaceuticals) 10-Year RORE % : 8.55% (As of Mar. 2026)


AGIO Agios Pharmaceuticals Inc AGIO
49 GF Score
Price $41.23
GF Value $84.32
Valuation Possible Value Trap
! 5 Warning Signs
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What is Agios Pharmaceuticals 10-Year RORE %?

Agios Pharmaceuticals AGIO -3.65% 49 10-Year RORE % is 8.55 as of Mar. 2026. GuruFocus rates AGIO with a GF Score™ of 49/100 and a GF Value™ of $84.32 (Possible Value Trap). The stock has 5 warning signs investors should review. Among 613 Biotechnology companies, Agios Pharmaceuticals ranks better than 78.47% on this metric.

Return on Retained Earnings (RORE) is an indicator of a company's growth potential, it shows how much a company earns by reinvesting its retained earnings, i.e. profits after dividend payments. Agios Pharmaceuticals's 10-Year RORE % for the quarter that ended in Mar. 2026 was 8.55%.

The industry rank for Agios Pharmaceuticals's 10-Year RORE % or its related term are showing as below:

AGIO's 10-Year RORE % is ranked better than
78.47% of 613 companies
in the Biotechnology industry
Industry Median: -6.35 vs AGIO: 8.55

Agios Pharmaceuticals  (NAS:AGIO) 10-Year RORE % Explanation

Return on Retained Earnings (RORE) is important to investors because it reveals a company's efficiency and growth potential. A higher RORE indicates a higher return. A high RORE indicates that the company should reinvest profits into the business. A lower RORE suggests that the company should distribute profits to shareholders by paying out dividends, since those dollars aren't generating much additional growth for the company.

There are a several different ways to arrive at the Return on Retained Earnings. The simplest way to calculate it is by using published information on Earnings per Share (EPS) and Dividend per Share (DPS) over a selected period. Here, 10-year period is chosen.

Be Aware

Please keep in mind that the RORE is relative to the nature of the business and its competitors. If another company in the same sector is producing a lower return on retained earnings, it doesn’t necessarily mean it’s a bad investment. It may just suggest the company is older and no longer in a high growth stage. At such a stage in the business cycle, it would be expected to see a lower RORE and higher dividend payout.


Agios Pharmaceuticals 10-Year RORE % Related Terms


Agios Pharmaceuticals 10-Year RORE % Historical Data

* Premium members only.

The historical data trend for Agios Pharmaceuticals's 10-Year RORE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Agios Pharmaceuticals 10-Year RORE % Chart

Agios Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
10-Year RORE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -157.71 14.54 21.12 -151.36 15.21

Agios Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
10-Year RORE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -135.25 -126.29 17.31 15.21 8.55

AGIO vs ABCL, KOD, IMNM: 10-Year RORE % Comparison

For the Biotechnology subindustry, Agios Pharmaceuticals's 10-Year RORE %, along with its competitors' market caps and 10-Year RORE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Agios Pharmaceuticals 10-Year RORE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Agios Pharmaceuticals's 10-Year RORE % distribution charts can be found below:

* The bar in red indicates where Agios Pharmaceuticals's 10-Year RORE % falls into.


AGIO
49GF Score
Agios Pharmaceuticals Inc AGIO
10-Year RORE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Agios Pharmaceuticals 10-Year RORE % Calculation

Agios Pharmaceuticals's 10-Year RORE % for the quarter that ended in Mar. 2026 is calculated as:

10-Year RORE %=( Most Recent EPS (Diluted)- First Period EPS (Diluted) )/( Cumulative EPS (Diluted) for 10-year -Cumulative Dividends per Share for 10-year )
=( -7.25--6 )/( -14.62-0 )
=-1.25/-14.62
=8.55 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of 10-Year RORE %, the most recent and first period EPS (Diluted) is the trailing twelve months (TTM) data ended in Mar. 2026 and 10-year before.

Frequently Asked Questions Learn more about 10-Year RORE % →
What does a 10-Year RORE % of 8.55 mean?
Agios Pharmaceuticals (AGIO) has a 10-Year RORE % of 8.55 as of Mar. 2026. 10-Year RORE % shows how much a company earns by reinvesting its retained earnings in 10-year. View historical data on Agios Pharmaceuticals and its competitors. According to the industry distribution chart, Agios Pharmaceuticals ranks #132 out of 613 companies in the Biotechnology industry, placing it in the top 21.5%.
Is Agios Pharmaceuticals' 10-Year RORE % too high?
Agios Pharmaceuticals' current 10-Year RORE % is 8.55. Based on the distribution chart, Agios Pharmaceuticals ranks #132 out of 613 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Agios Pharmaceuticals has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Agios Pharmaceuticals' 10-Year RORE % compare to ABCL and KOD?
According to the Biotechnology industry distribution chart, Agios Pharmaceuticals ranks #132 out of 613 companies for 10-Year RORE %. This places Agios Pharmaceuticals in the top 22% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 10-Year RORE % for a Biotechnology company?
A good 10-Year RORE % depends on the Biotechnology industry context. However, 10-Year RORE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 10-Year RORE % mean?
A high 10-Year RORE % can signal that a stock is expensive relative to its fundamentals. 10-Year RORE % shows how much a company earns by reinvesting its retained earnings in 10-year. View historical data on Agios Pharmaceuticals and its competitors. Agios Pharmaceuticals's current 10-Year RORE % is 8.55. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Agios Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Agios Pharmaceuticals (AGIO) is currently considered Possible Value Trap. The stock's GF Value™ is $84.32, compared to a current price of $41.23 — trading 51.1% below its estimated fair value. The current 10-Year RORE % is 8.55. Agios Pharmaceuticals' overall GF Score™ is 49/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 10-Year RORE % calculated?
10-Year RORE % is calculated from a company's financial statements. For Agios Pharmaceuticals (AGIO), the current 10-Year RORE % is 8.55 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Agios Pharmaceuticals (AGIO) Overvalued in 2026?

Based on GuruFocus' analysis, Agios Pharmaceuticals stock appears to be undervalued. The current stock price of $41.23 is trading 51.1% below its estimated GF Value™ of $84.32. GuruFocus considers Agios Pharmaceuticals to be Possible Value Trap.

Key valuation signals for AGIO:

  • 10-Year RORE %: 8.55
  • GF Value™: $84.32 vs. price of $41.23 (51.1% below fair value)
  • GF Score™: 49/100 with 5 warning signs

No single metric tells the full story. See the AGIO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Agios Pharmaceuticals Business Description

Other Exchanges 0HB0:UK8AP:Germany
Address 88 Sidney Street, Cambridge, MA, USA, 02139
Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.
49GF Score

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10-Year RORE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$41.23
Price
$84.32
GF Value