OncoTherapy Science (TSE:4564) 3-Year RORE % : -26.85% (As of Mar. 2026)

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TSE:4564 OncoTherapy Science Inc TSE:4564
50 GF Score
Price 円20.00
GF Value 円16.90
Valuation Modestly Overvalued
! 1 Warning Sign
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What is OncoTherapy Science 3-Year RORE %?

OncoTherapy Science TSE:4564 -4.76% 50 3-Year RORE % is -26.85 as of Mar. 2026. GuruFocus rates TSE:4564 with a GF Score™ of 50/100 and a GF Value™ of 円16.90 (Modestly Overvalued). The stock has 1 warning sign investors should review. Among 1,291 Biotechnology companies, OncoTherapy Science ranks worse than 65.61% on this metric.

Return on Retained Earnings (RORE) is an indicator of a company's growth potential, it shows how much a company earns by reinvesting its retained earnings, i.e. profits after dividend payments. OncoTherapy Science's 3-Year RORE % for the quarter that ended in Mar. 2026 was -26.85%.

The industry rank for OncoTherapy Science's 3-Year RORE % or its related term are showing as below:

TSE:4564's 3-Year RORE % is ranked worse than
65.61% of 1291 companies
in the Biotechnology industry
Industry Median: -11.44 vs TSE:4564: -26.85

OncoTherapy Science  (TSE:4564) 3-Year RORE % Explanation

Return on Retained Earnings (RORE) is important to investors because it reveals a company's efficiency and growth potential. A higher RORE indicates a higher return. A high RORE indicates that the company should reinvest profits into the business. A lower RORE suggests that the company should distribute profits to shareholders by paying out dividends, since those dollars aren't generating much additional growth for the company.

There are a several different ways to arrive at the Return on Retained Earnings. The simplest way to calculate it is by using published information on Earnings per Share (EPS) and Dividend per Share (DPS) over a selected period. Here, 3-year period is chosen.

Be Aware

Please keep in mind that the RORE is relative to the nature of the business and its competitors. If another company in the same sector is producing a lower return on retained earnings, it doesn’t necessarily mean it’s a bad investment. It may just suggest the company is older and no longer in a high growth stage. At such a stage in the business cycle, it would be expected to see a lower RORE and higher dividend payout.


OncoTherapy Science 3-Year RORE % Related Terms


OncoTherapy Science 3-Year RORE % Historical Data

* Premium members only.

The historical data trend for OncoTherapy Science's 3-Year RORE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

OncoTherapy Science 3-Year RORE % Chart

OncoTherapy Science Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
3-Year RORE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -0.03 -10.74 -29.98 -17.55 -26.85

OncoTherapy Science Semi-Annual Data
Sep16 Mar17 Sep17 Mar18 Sep18 Mar19 Sep19 Mar20 Sep20 Mar21 Sep21 Mar22 Sep22 Mar23 Sep23 Mar24 Sep24 Mar25 Sep25 Mar26
3-Year RORE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -29.98 -25.50 -17.55 -23.00 -26.85

TSE:4564 vs VRTX, REGN, ALNY: 3-Year RORE % Comparison

For the Biotechnology subindustry, OncoTherapy Science's 3-Year RORE %, along with its competitors' market caps and 3-Year RORE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


OncoTherapy Science 3-Year RORE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, OncoTherapy Science's 3-Year RORE % distribution charts can be found below:

* The bar in red indicates where OncoTherapy Science's 3-Year RORE % falls into.


TSE:4564
50GF Score
OncoTherapy Science Inc TSE:4564
3-Year RORE % is just one metric. See GF Score™, valuation, warning signs, and more.
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OncoTherapy Science 3-Year RORE % Calculation

OncoTherapy Science's 3-Year RORE % for the quarter that ended in Mar. 2026 is calculated as:

3-Year RORE %=( Most Recent EPS (Diluted)- First Period EPS (Diluted) )/( Cumulative EPS (Diluted) for 3-year -Cumulative Dividends per Share for 3-year )
=( -2.817--6.05 )/( -12.039-0 )
=3.233/-12.039
=-26.85 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of 3-Year RORE %, the most recent and first period EPS (Diluted) is the trailing twelve months (TTM) data ended in Mar. 2026 and 3-year before.

Frequently Asked Questions Learn more about 3-Year RORE % →
What does a 3-Year RORE % of -26.85 mean?
OncoTherapy Science (TSE:4564) has a 3-Year RORE % of -26.85 as of Mar. 2026. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on OncoTherapy Science and its competitors. According to the industry distribution chart, OncoTherapy Science ranks #847 out of 1291 companies in the Biotechnology industry, placing it in the top 65.6%.
Is OncoTherapy Science's 3-Year RORE % too high?
OncoTherapy Science's current 3-Year RORE % is -26.85. Based on the distribution chart, OncoTherapy Science ranks #847 out of 1291 companies in the Biotechnology industry, which is below the industry midpoint. Overall, OncoTherapy Science has a GF Score™ of 50/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OncoTherapy Science's 3-Year RORE % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, OncoTherapy Science ranks #847 out of 1291 companies for 3-Year RORE %. This places OncoTherapy Science in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year RORE % for a Biotechnology company?
A good 3-Year RORE % depends on the Biotechnology industry context. However, 3-Year RORE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year RORE % mean?
A high 3-Year RORE % can signal that a stock is expensive relative to its fundamentals. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on OncoTherapy Science and its competitors. OncoTherapy Science's current 3-Year RORE % is -26.85. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OncoTherapy Science stock overvalued right now?
Based on GuruFocus' analysis, OncoTherapy Science (TSE:4564) is currently considered Modestly Overvalued. The stock's GF Value™ is 円16.90, compared to a current price of 円20.00 — trading 18.3% above its estimated fair value. The current 3-Year RORE % is -26.85. OncoTherapy Science's overall GF Score™ is 50/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year RORE % calculated?
3-Year RORE % is calculated from a company's financial statements. For OncoTherapy Science (TSE:4564), the current 3-Year RORE % is -26.85 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is OncoTherapy Science (TSE:4564) Overvalued in 2026?

Based on GuruFocus' analysis, OncoTherapy Science stock appears to be overvalued. The current stock price of 円20.00 is trading 18.3% above its estimated GF Value™ of 円16.90. GuruFocus considers OncoTherapy Science to be Modestly Overvalued.

Key valuation signals for TSE:4564:

  • 3-Year RORE %: -26.85
  • GF Value™: 円16.90 vs. price of 円20.00 (18.3% above fair value)
  • GF Score™: 50/100 with 1 warning sign

No single metric tells the full story. See the TSE:4564 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


OncoTherapy Science Business Description

Other Exchanges 30O:Germany
Address 11th Floor, Kanagawa Science Park R&D, 3-2-1 Sakado, Kanagawa, Kawasaki, JPN, 213-0012
OncoTherapy Science Inc focuses on cancer-related cells and genes and develops cancer therapy products which include low molecular drugs, antibody drugs, cancer peptide vaccine, and diagnostic medicine in Japan.
50GF Score

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3-Year RORE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円20.00
Price
円16.90
GF Value