ALPMF (Astellas Pharma) Shiller PE Ratio: 24.75 (As of Sep. 07, 2026) — 10% Above Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ALPMF Astellas Pharma Inc ALPMF
85 GF Score
Price $15.10
GF Value $15.39
Valuation Fairly Valued
! 5 Warning Signs
View Full Analysis

What is Astellas Pharma Shiller PE Ratio?

Astellas Pharma ALPMF +1.96% 85 Shiller PE Ratio is 24.75 as of Sep. 07, 2026, which is 10% above its 10-year median of 22.58. GuruFocus rates ALPMF with a GF Score™ of 85/100 and a GF Value™ of $15.39 (Fairly Valued). The stock has 5 warning signs investors should review. Among 527 Drug Manufacturers companies, Astellas Pharma ranks worse than 50.85% on this metric.

As of today (2026-09-07), Astellas Pharma's current share price is $15.10. Astellas Pharma's E10 for the quarter that ended in Jun. 2026 was $0.61. Astellas Pharma's Shiller PE Ratio for today is 24.75.

The historical rank and industry rank for Astellas Pharma's Shiller PE Ratio or its related term are showing as below:

ALPMF' s Shiller PE Ratio Range Over the Past 10 Years
Min: 15.95   Med: 22.58   Max: 30.3
Current: 25.69

During the past years, Astellas Pharma's highest Shiller PE Ratio was 30.30. The lowest was 15.95. And the median was 22.58.

ALPMF's Shiller PE Ratio is ranked worse than
50.85% of 527 companies
in the Drug Manufacturers industry
Industry Median: 25.48 vs ALPMF: 25.69

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Astellas Pharma's adjusted earnings per share data for the three months ended in Jun. 2026 was $0.491. Add all the adjusted EPS for the past 10 years together and divide 10 will get our E10, which is $0.61 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Astellas Pharma  (OTCPK:ALPMF) Shiller PE Ratio Explanation

Compared with the regular PE Ratio, which works poorly for cyclical businesses, the Shiller PE Ratio smoothed out the fluctuations of profit margins during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Shiller PE Ratio should give similar results to regular PE Ratio.

Compared with the PS Ratio, the Shiller PE Ratio makes the comparison between different industries more meaningful.


Be Aware

Shiller PE Ratio assumes that over the long term, businesses and profitability revert to their means. If a company's business model does not work in the future compared with the past, Shiller PE Ratio and PS Ratio will give false valuations.


Astellas Pharma Shiller PE Ratio Related Terms


Astellas Pharma Shiller PE Ratio Historical Data

* Premium members only.

The historical data trend for Astellas Pharma's Shiller PE Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Astellas Pharma Shiller PE Ratio Chart

Astellas Pharma Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
Shiller PE Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 22.98 21.66 20.38 18.18 29.05

Astellas Pharma Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Shiller PE Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 17.38 19.27 24.31 29.05 23.73

ALPMF vs LLY, JNJ, ABBV: Shiller PE Ratio Comparison

For the Drug Manufacturers - General subindustry, Astellas Pharma's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Astellas Pharma Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Astellas Pharma's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Astellas Pharma's Shiller PE Ratio falls into.


ALPMF
85GF Score
Astellas Pharma Inc ALPMF
Shiller PE Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Astellas Pharma Shiller PE Ratio Calculation

For Shiller PE Ratio, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller PE Ratio is also called PE10.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Astellas Pharma's Shiller PE Ratio for today is calculated as

Shiller PE Ratio=Share Price/ E10
=15.10/0.61
=24.75

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Astellas Pharma's E10 for the quarter that ended in Jun. 2026 is calculated as:

For example, Astellas Pharma's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS=Earnings per Share (Diluted)/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0.491/113.6000*113.6000
=0.491

Current CPI (Jun. 2026) = 113.6000.

Astellas Pharma Quarterly Data

Earnings per Share (Diluted) CPI Adj_EPS
201609 0.224 98.000 0.260
201612 0.260 98.400 0.300
201703 0.171 98.100 0.198
201706 0.185 98.500 0.213
201709 0.175 98.800 0.201
201712 0.265 99.400 0.303
201803 0.106 99.200 0.121
201806 0.251 99.200 0.287
201809 0.227 99.900 0.258
201812 0.406 99.700 0.463
201903 0.148 99.700 0.169
201906 0.287 99.800 0.327
201909 0.345 100.100 0.392
201912 0.300 100.500 0.339
202003 0.030 100.300 0.034
202006 0.252 99.900 0.287
202009 0.114 99.900 0.130
202012 0.311 99.300 0.356
202103 -0.061 99.900 -0.069
202106 0.150 99.500 0.171
202109 0.200 100.100 0.227
202112 0.288 100.100 0.327
202203 -0.037 101.100 -0.042
202206 0.101 101.800 0.113
202209 0.274 103.100 0.302
202212 0.197 104.100 0.215
202303 -0.189 104.400 -0.206
202306 0.130 105.200 0.140
202309 -0.005 106.200 -0.005
202312 0.056 106.800 0.060
202403 -0.124 107.200 -0.131
202406 0.133 108.200 0.140
202409 0.140 108.900 0.146
202412 -0.354 110.700 -0.363
202503 0.280 111.100 0.286
202506 0.264 111.700 0.268
202509 0.298 112.000 0.302
202512 0.358 113.000 0.360
202603 0.153 112.700 0.154
202606 0.491 113.600 0.491

Add all the adjusted EPS together and divide 10 will get our E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Frequently Asked Questions Learn more about Shiller PE Ratio →
What does a Shiller PE Ratio of 24.75 mean?
Astellas Pharma (ALPMF) has a Shiller PE Ratio of 24.75 as of Sep. 07, 2026. Shiller price-earnings ratio is the ratio of share price to a company's inflation-adjusted earnings over a 10-year period. View historical data on Astellas Pharma and its competitors. This is 10% above median its historical median of 22.58. Over the past decade, Astellas Pharma's Shiller PE Ratio has ranged from 15.95 to 30.30. According to the industry distribution chart, Astellas Pharma ranks #268 out of 527 companies in the Drug Manufacturers industry, placing it in the top 50.9%.
Is Astellas Pharma's Shiller PE Ratio too high?
Astellas Pharma's current Shiller PE Ratio of 24.75 is 10% above median its 10-year median of 22.58. Over the past 10 years, this metric has ranged from a low of 15.95 to a high of 30.30. The Drug Manufacturers industry median Shiller PE Ratio is 25.48. Astellas Pharma's value of 24.75 is 2.9% below this industry median. Based on the distribution chart, Astellas Pharma ranks #268 out of 527 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Astellas Pharma has a GF Score™ of 85/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Astellas Pharma's Shiller PE Ratio compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, Astellas Pharma ranks #268 out of 527 companies for Shiller PE Ratio. This places Astellas Pharma in the lower half of its industry. The industry median Shiller PE Ratio is 25.48. Astellas Pharma's value of 24.75 is 2.9% below this benchmark. Historically, Astellas Pharma's own Shiller PE Ratio has ranged from 15.95 to 30.30 over the past decade. While the company's 10-year median is 22.58 vs. the industry median of 25.48, Astellas Pharma has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Shiller PE Ratio for a Drug Manufacturers company?
The median Shiller PE Ratio among Drug Manufacturers companies is 25.48, based on 527 companies in the industry. Companies in the top quartile (top 25%) have a Shiller PE Ratio significantly above this median, while those in the bottom quartile fall well below. However, Shiller PE Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Astellas Pharma's current Shiller PE Ratio of 24.75 is 2.9% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Shiller PE Ratio mean?
A high Shiller PE Ratio can signal that a stock is expensive relative to its fundamentals. Shiller price-earnings ratio is the ratio of share price to a company's inflation-adjusted earnings over a 10-year period. View historical data on Astellas Pharma and its competitors. For the Drug Manufacturers industry, the median Shiller PE Ratio is 25.48 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Astellas Pharma's current Shiller PE Ratio is 24.75, which is 10% above median its own 10-year median of 22.58. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Astellas Pharma stock overvalued right now?
Based on GuruFocus' analysis, Astellas Pharma (ALPMF) is currently considered Fairly Valued. The stock's GF Value™ is $15.39, compared to a current price of $15.10 — trading 1.9% below its estimated fair value. The current Shiller PE Ratio is 24.75, which is 10% above median its 10-year median of 22.58 and 2.9% below the Drug Manufacturers industry median of 25.48. Astellas Pharma's overall GF Score™ is 85/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Shiller PE Ratio calculated?
Shiller PE Ratio is calculated from a company's financial statements. For Astellas Pharma (ALPMF), the current Shiller PE Ratio is 24.75 as of Sep. 07, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Astellas Pharma (ALPMF) Overvalued in 2026?

Based on GuruFocus' analysis, Astellas Pharma stock appears to be undervalued. The current stock price of $15.10 is trading 1.9% below its estimated GF Value™ of $15.39. GuruFocus considers Astellas Pharma to be Fairly Valued.

Key valuation signals for ALPMF:

  • Shiller PE Ratio: 24.75 (10% above median its 10-year median of 22.58)
  • GF Value™: $15.39 vs. price of $15.10 (1.9% below fair value)
  • GF Score™: 85/100 with 5 warning signs
  • Industry Position: 2.9% below the Drug Manufacturers median (#268 of 527)

No single metric tells the full story. See the ALPMF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Astellas Pharma Business Description

Address 2-5-1 Nihonbashi-Honcho, Chuo-ku, Tokyo, JPN, 103-8411
Astellas Pharma Inc is a specialty international pharmaceutical company. The company focuses on accelerating the discovery, development, and commercialization of ground-breaking innovations that could redefine expectations of care for difficult-to-treat diseases. The group is committed to driving innovation in immuno-oncology, gene therapy, mitochondria, blindness and regeneration, and targeted protein degradation. Its core products include anticancer agents like XTANDI, XOSPATA, and PADCEV; VEOZAH for the treatment of vasomotor symptoms due to menopause; Betanis / Myrbetriq / BETMIGA for the treatment of overactive bladder (OAB); and Prograf, an immunosuppressant for organ transplantation.
85GF Score

Get the complete analysis for ALPMF

Shiller PE Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$15.10
Price
$15.39
GF Value