LPCN (Lipocine) Shiller PE Ratio: (As of Sep. 14, 2026)

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LPCN Lipocine Inc LPCN
49 GF Score
Price $2.20
GF Value $1.33
Valuation Significantly Overvalued
! 4 Warning Signs
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What is Lipocine Shiller PE Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


Lipocine  (NAS:LPCN) Shiller PE Ratio Explanation

Compared with the regular PE Ratio, which works poorly for cyclical businesses, the Shiller PE Ratio smoothed out the fluctuations of profit margins during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Shiller PE Ratio should give similar results to regular PE Ratio.

Compared with the PS Ratio, the Shiller PE Ratio makes the comparison between different industries more meaningful.


Be Aware

Shiller PE Ratio assumes that over the long term, businesses and profitability revert to their means. If a company's business model does not work in the future compared with the past, Shiller PE Ratio and PS Ratio will give false valuations.


Lipocine Shiller PE Ratio Related Terms


Lipocine Shiller PE Ratio Historical Data

* Premium members only.

The historical data trend for Lipocine's Shiller PE Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lipocine Shiller PE Ratio Chart

Lipocine Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Shiller PE Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

Lipocine Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Shiller PE Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

LPCN vs TPST, CYCN, BCDA: Shiller PE Ratio Comparison

For the Biotechnology subindustry, Lipocine's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Lipocine Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Lipocine's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Lipocine's Shiller PE Ratio falls into.


LPCN
49GF Score
Lipocine Inc LPCN
Shiller PE Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Lipocine Shiller PE Ratio Calculation

For Shiller PE Ratio, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller PE Ratio is also called PE10.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Lipocine's E10 for the quarter that ended in Jun. 2026 is calculated as:

For example, Lipocine's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS=Earnings per Share (Diluted)/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=-0.32/333.9520*333.9520
=-0.320

Current CPI (Jun. 2026) = 333.9520.

Lipocine Quarterly Data

Earnings per Share (Diluted) CPI Adj_EPS
201609 -3.060 241.428 -4.233
201612 -2.720 241.432 -3.762
201703 -4.420 243.801 -6.054
201706 -5.270 244.955 -7.185
201709 -3.740 246.819 -5.060
201712 -4.250 246.524 -5.757
201803 -2.210 249.554 -2.957
201806 -2.550 251.989 -3.379
201809 -2.040 252.439 -2.699
201812 -2.550 251.233 -3.390
201903 -2.380 254.202 -3.127
201906 -2.380 256.143 -3.103
201909 -2.040 256.759 -2.653
201912 -1.700 256.974 -2.209
202003 -2.380 258.115 -3.079
202006 -2.210 257.797 -2.863
202009 -1.190 260.280 -1.527
202012 -1.020 260.474 -1.308
202103 -0.680 264.877 -0.857
202106 -1.360 271.696 -1.672
202109 -0.680 274.310 -0.828
202112 2.380 278.802 2.851
202203 -0.680 287.504 -0.790
202206 -0.610 296.311 -0.687
202209 -0.520 296.808 -0.585
202212 -0.430 296.797 -0.484
202303 -0.760 301.836 -0.841
202306 -0.680 305.109 -0.744
202309 -1.270 307.789 -1.378
202312 -0.420 306.746 -0.457
202403 0.660 312.332 0.706
202406 -0.570 314.175 -0.606
202409 -0.440 315.301 -0.466
202412 0.330 315.605 0.349
202503 -0.350 319.799 -0.365
202506 -0.410 322.561 -0.424
202509 -0.590 324.800 -0.607
202512 -0.420 324.054 -0.433
202603 -0.540 330.213 -0.546
202606 -0.320 333.952 -0.320

Add all the adjusted EPS together and divide 10 will get our E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is Lipocine (LPCN) Overvalued in 2026?

Based on GuruFocus' analysis, Lipocine stock appears to be overvalued. The current stock price of $2.20 is trading 65.4% above its estimated GF Value™ of $1.33. GuruFocus considers Lipocine to be Significantly Overvalued.

Key valuation signals for LPCN:

  • Shiller PE Ratio:
  • GF Value™: $1.33 vs. price of $2.20 (65.4% above fair value)
  • GF Score™: 49/100 with 4 warning signs

No single metric tells the full story. See the LPCN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Lipocine Business Description

Address 675 Arapeen Drive, Suite 202, Salt Lake City, UT, USA, 84108
Lipocine Inc is a clinical-stage biopharmaceutical company that is engaged in research and development for the delivery of drugs using its proprietary delivery technology. Its principal operation is to provide oral delivery solutions for existing drugs. Lipocine develops its drug candidates, or it develops drug candidates on behalf of or in collaboration with corporate partners. The company's product TLANDO is an oral testosterone replacement therapy (TRT). It also has other products in the pipeline, such as LPCN 1144, TLANDO, TLANDO XR, LPCN 1148, LPCN 1107, LPCN 1154, and LIP RAL7 Technology. The Company has a single reportable segment, research, and development for the delivery of drugs using its proprietary delivery technology.
49GF Score

Get the complete analysis for LPCN

Shiller PE Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.20
Price
$1.33
GF Value