INO (Inovio Pharmaceuticals) 3-Year Share Buyback Ratio: -48.40% (As of Jun. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

INO Inovio Pharmaceuticals Inc INO
43 GF Score
Price $1.18
GF Value $0.21
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is Inovio Pharmaceuticals 3-Year Share Buyback Ratio?

Inovio Pharmaceuticals INO -2.48% 43 3-Year Share Buyback Ratio is -48.40 as of Jun. 2026. GuruFocus rates INO with a GF Score™ of 43/100 and a GF Value™ of $0.21 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 1,190 Biotechnology companies, Inovio Pharmaceuticals ranks worse than 83.11% on this metric.

Shares Outstanding (EOP) are shares that have been authorized, issued, and purchased by investors and are held by them.

3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. A positive ratio may indicate share buybacks over the period, while a zero or negative ratio may reflect no repurchases or potential share issuance. Inovio Pharmaceuticals's current 3-Year Share Buyback Ratio was -48.40%.

The historical rank and industry rank for Inovio Pharmaceuticals's 3-Year Share Buyback Ratio or its related term are showing as below:

INO' s 3-Year Share Buyback Ratio Range Over the Past 10 Years
Min: -48.4   Med: -28.55   Max: -10.4
Current: -48.4

During the past 13 years, Inovio Pharmaceuticals's highest 3-Year Share Buyback Ratio was -10.40%. The lowest was -48.40%. And the median was -28.55%.

INO's 3-Year Share Buyback Ratio is ranked worse than
83.11% of 1190 companies
in the Biotechnology industry
Industry Median: -11.8 vs INO: -48.40

Inovio Pharmaceuticals (NAS:INO) 3-Year Share Buyback Ratio Explanation

A negative number means the company might be issuing new shares. A positive number indicates that the company is buying back shares.


Be Aware

Investors usually like share buybacks. But as pointed by Warren Buffett, only if a company buys back shares at the prices below the stock's intrinsic value, it rewards remaining shareholders. If a company buys its overvalued stocks back, it destroys shareholder value.


Inovio Pharmaceuticals 3-Year Share Buyback Ratio Related Terms


INO vs TELO, ELTX, ALPS: 3-Year Share Buyback Ratio Comparison

For the Biotechnology subindustry, Inovio Pharmaceuticals's 3-Year Share Buyback Ratio, along with its competitors' market caps and 3-Year Share Buyback Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Inovio Pharmaceuticals 3-Year Share Buyback Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Inovio Pharmaceuticals's 3-Year Share Buyback Ratio distribution charts can be found below:

* The bar in red indicates where Inovio Pharmaceuticals's 3-Year Share Buyback Ratio falls into.


INO
43GF Score
Inovio Pharmaceuticals Inc INO
3-Year Share Buyback Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Inovio Pharmaceuticals 3-Year Share Buyback Ratio Calculation

This is the annualized percentage change in shares outstanding from three years ago to the current year. The annualized percentage change is calculated with expontential compound based on the latest four years of annual data on Shares Outstanding (EOP).

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the average dividends per share growth rate.

What does a 3-Year Share Buyback Ratio of -48.40 mean?
Inovio Pharmaceuticals (INO) has a 3-Year Share Buyback Ratio of -48.40 as of Jun. 2026. The 3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. View historical data for Inovio Pharmaceuticals and its competitors. According to the industry distribution chart, Inovio Pharmaceuticals ranks #989 out of 1190 companies in the Biotechnology industry, placing it in the top 83.1%.
Is Inovio Pharmaceuticals' 3-Year Share Buyback Ratio too high?
Inovio Pharmaceuticals' current 3-Year Share Buyback Ratio is -48.40. Based on the distribution chart, Inovio Pharmaceuticals ranks #989 out of 1190 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Inovio Pharmaceuticals has a GF Score™ of 43/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Inovio Pharmaceuticals' 3-Year Share Buyback Ratio compare to TELO and ELTX?
According to the Biotechnology industry distribution chart, Inovio Pharmaceuticals ranks #989 out of 1190 companies for 3-Year Share Buyback Ratio. This places Inovio Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year Share Buyback Ratio for a Biotechnology company?
A good 3-Year Share Buyback Ratio depends on the Biotechnology industry context. However, 3-Year Share Buyback Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year Share Buyback Ratio mean?
A high 3-Year Share Buyback Ratio can signal that a stock is expensive relative to its fundamentals. The 3-Year Share Buyback Ratio measures the average annual proportion of a company's outstanding shares repurchased over the past three years. It is calculated as the annualized percentage change in shares outstanding from three years ago to the current year. View historical data for Inovio Pharmaceuticals and its competitors. Inovio Pharmaceuticals's current 3-Year Share Buyback Ratio is -48.40. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Inovio Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Inovio Pharmaceuticals (INO) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.21, compared to a current price of $1.18 — trading 461.9% above its estimated fair value. The current 3-Year Share Buyback Ratio is -48.40. Inovio Pharmaceuticals' overall GF Score™ is 43/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year Share Buyback Ratio calculated?
3-Year Share Buyback Ratio is calculated from a company's financial statements. For Inovio Pharmaceuticals (INO), the current 3-Year Share Buyback Ratio is -48.40 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Inovio Pharmaceuticals (INO) Overvalued in 2026?

Based on GuruFocus' analysis, Inovio Pharmaceuticals stock appears to be overvalued. The current stock price of $1.18 is trading 461.9% above its estimated GF Value™ of $0.21. GuruFocus considers Inovio Pharmaceuticals to be Significantly Overvalued.

Key valuation signals for INO:

  • 3-Year Share Buyback Ratio: -48.40
  • GF Value™: $0.21 vs. price of $1.18 (461.9% above fair value)
  • GF Score™: 43/100 with 4 warning signs

No single metric tells the full story. See the INO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Inovio Pharmaceuticals Business Description

Address 660 West Germantown Pike, Suite 110, Plymouth Meeting, PA, USA, 19462
Inovio Pharmaceuticals Inc is a clinical-stage biotechnology company focused on developing and commercializing DNA medicines to help treat and protect people from diseases associated with human papillomavirus (HPV), cancer and infectious diseases. INOVIO's platform harnesses the power of in vivo protein production, featuring optimized design and delivery of DNA medicines that teach the body to manufacture its own disease-fighting tools. Its candidate is INO-3107 for the treatment of recurrent respiratory papillomatosis (RRP), a chronic, rare and debilitating disease of the respiratory tract caused by HPV infection. In its completed Phase 1/2 clinical trial of INO-3107 for the treatment of HPV-6 and HPV-11-associated RRP.
43GF Score

Get the complete analysis for INO

3-Year Share Buyback Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.18
Price
$0.21
GF Value