Insider List

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Total 41

Insider Name
Alexander J Denner
Anand Mehra
Beth Hecht
Brenton Karl Ahrens
Canaan Partners X Llc
Canaan X L.p.
Christine Coyne
David George Kelly
Fhm Vii, L.l.c.
Fhm Vii, L.p.
Fishman Corey N.
Frazier Healthcare Vii, L.p.
Frazier Healthcare Vii-a, L.p.
James Healy
Jeffrey R. Schaffnit
Joseph John Whalen
Judith M. Matthews
Liam Ratcliffe
Mark Chin
Michael Powell
Michael W. Dunne
New Leaf Venture Associates Iii, L.p.
New Leaf Venture Management Iii, L.l.c.
New Leaf Ventures Iii, L.p.
Patrick J Heron
Paul R Edick
Peter Kolchinsky
Ra Capital Healthcare Fund Lp
Ra Capital Management, L.p.
Rajeev M. Shah
Ronald Hunt
Sailaja Puttagunta
Sarissa Capital Catapult Fund Llc
Sarissa Capital Hawkeye Fund Lp
Sarissa Capital Management Lp
Sarissa Capital Master Fund Ii Lp
Sarissa Capital Offshore Master Fund Lp
Shahzad Malik
Sofinnova Management Ix, L.l.c.
Sofinnova Venture Partners Ix, L.p.

Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
Alexander J Denner	2023-06-15	3.410	3.410	31.310	50.570	4.600	-13.470	0.430	7.240	22.490	34.030	-7.150	-24.730	BIIB MDCO RGLS SEELQ BIVV ARIA ... VVUSQ ENZN SVRA SRSAU IRWD ITRM SRSA INVA
Anand Mehra	2024-11-19	-4.910	-4.910	-5.740	41.900	15.600	20.170	-4.590	10.570	-9.770	32.980	4.460	8.080	MRUS ACRS ONCE NXTC GRTX ETTX ... PRNB ITRM MRNS SYBX ATYR AERI OCGN ALIM ARAV
Beth Hecht	2020-03-13	-19.390	-19.390	45.120	42.420	-12.180	-30.170	-14.040	37.090	35.720	14.580	-31.250	-42.010	XERS NEOS AYTU ITRM
Brenton Karl Ahrens	2018-05-30	-12.180	-12.180	-48.400	-44.450	-41.140	-50.800	-11.970	-22.710	-49.730	-46.830	-46.860	-66.380	ITRM DXCM
Canaan Partners X Llc		-	-	-	-	-	-	-	-	-	-	-	-	ITRM IDYA NXTC PTGX ASTR
Canaan X L.p.	2019-05-28	-4.860	-4.860	10.840	4.110	-13.750	-24.870	-6.310	17.440	2.930	-1.910	-29.570	-37.920	ITRM IDYA NXTC PTGX ASTR
Christine Coyne		-	-	-	-	-	-	-	-	-	-	-	-	SCYX ITRM
David George Kelly	2018-11-30	-12.280	-12.280	7.640	-61.890	-65.790	-57.180	-2.340	-13.220	6.600	-75.690	-80.320	-75.440	ITRM HZNP
Fhm Vii, L.l.c.		-	-	-	-	-	-	-	-	-	-	-	-	ITRM ANAB IMGO
Fhm Vii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ITRM ANAB IMGO
Fishman Corey N.	2023-11-20	2.370	2.370	-25.550	-12.910	-54.890	-54.060	0.880	-18.280	-30.700	-24.160	-62.210	-69.840	BSTC MNTA ITRM
Frazier Healthcare Vii, L.p.	2017-01-31	33.690	33.690	43.540	521.770	97.810	-5.030	29.120	49.890	35.140	497.860	88.880	-17.310	ITRM ANAB IMGO
Frazier Healthcare Vii-a, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ITRM ANAB IMGO
James Healy	2024-09-27	-2.640	-2.640	4.250	11.450	7.020	-11.560	-3.060	-8.090	2.490	2.980	-3.300	-20.500	CHRS KRTX CMPI INZY AKUS YMAB ... NTRA ITRM NXTC GRTX ETTX PRNB PDSB MRNS AMRN ACRS SYBX ATYR ONCE OCGN ALIM AERI ARAV OCRX ANTH HGENQ PRTK MTEMQ BOLT AVTE VERA CINC RAPP BIOA JBIO AVBP
Jeffrey R. Schaffnit		-	-	-	-	-	-	-	-	-	-	-	-	ITRM
Joseph John Whalen	2025-03-10	-	-	-	-	-	-	-	-	-	-	-	-	ITRM
Judith M. Matthews	2018-05-30	-12.180	-12.180	-48.400	-44.450	-41.140	-50.800	-11.970	-22.710	-49.730	-46.830	-46.860	-66.380	ITRM
Liam Ratcliffe	2020-12-18	6.010	6.010	7.000	-5.790	-19.140	-11.590	9.660	25.330	2.770	-21.630	-29.700	-23.350	ARVN PASG COGT APTX PDSB ITRM ... DCPH IRTC LITS ARAV CMRX CNCE OXFD RLYP CLYM IRON UPB
Mark Chin	2021-10-13	-8.460	-8.460	-20.030	-46.890	-44.100	-42.280	-13.850	1.250	-31.320	-59.980	-58.210	-57.920	ITRM HARP IMRA PYXS IRON ELVN
Michael Powell	2020-08-11	6.720	6.720	114.050	71.030	-30.430	-45.620	7.770	13.500	109.330	61.650	-40.090	-50.430	CMPI INZY AKUS GRTX ITRM NXTC ... SYBX ETTX PRNB OCRX MRNS ACRS ATYR ONCE OCGN ALIM AERI ARAV HGENQ ANTH OREXQ AMRN MTEMQ PRTK SGEN BOLT VERA BCAX
Michael W. Dunne	2025-08-08	-11.320	-11.320	-37.420	-20.390	-54.150	-49.920	-11.430	-23.810	-43.350	-33.840	-64.330	-66.230	ITRM VXRT
New Leaf Venture Associates Iii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	DCPH HARP ARVN APTX ITRM PDSB
New Leaf Venture Management Iii, L.l.c.	2018-06-25	-0.250	-0.250	-8.450	-2.880	-11.050	-4.670	-3.630	28.700	-2.760	-14.360	-17.740	-17.740	DCPH HARP ARVN APTX ITRM PDSB
New Leaf Ventures Iii, L.p.	2021-01-11	-10.570	-10.570	-30.160	-27.790	-30.500	-40.050	-12.960	-17.940	-40.170	-51.380	-41.460	-52.630	DCPH HARP ARVN APTX ITRM PDSB
Patrick J Heron	2025-09-26	1.530	1.530	20.740	22.120	3.570	-14.250	2.280	4.560	10.820	5.620	-12.070	-24.730	TARS ITRM PCVX PHAT MIRM PASG ... ARQT ETTX ALPN APTX ANAB SRRA RGDO COLL GKOS CDTX IMGO FLAC HLVX FLACU MBX
Paul R Edick	2023-08-09	2.960	2.960	6.720	-5.970	-12.120	-14.650	2.570	-7.030	4.200	-16.390	-24.840	-25.470	MIST XERS ITRM PDLI SCMP NEOS ... LUMO
Peter Kolchinsky	2020-06-23	-10.530	-10.530	-9.150	165.390	-58.080	-	-11.420	9.750	-22.790	138.080	-68.180	-	PCVX CRDF PMVP DYN ETNB TGTX ... INBX WVE INZY ITOS PAND NKTX RACA RYTM AKUS VSTM FMTX RARX PHAT IMRA KALA SCPH THOR DRNA STSA EIGRQ ARVN EIDX KALV GTHX ACRS ACHN SGMO DSCI BSTC ARDMQ SQNM CRIS RXST ABOS VRDN DICE ITRM SLDB ORTX CLYM HOWL ICVX AVTE PNT VOR JANX RACB CTKB PEPG TYRA ANTX FULC SBTX ACRV SPRY ELVN MLYS BDTX SEPN CDTX FDMT BOLD JBIO LENZ ARTV BCAX SION
Ra Capital Healthcare Fund Lp	2025-09-26	6.720	6.720	2.560	14.310	-18.740	-20.290	5.420	-0.530	-4.850	-0.840	-33.430	-32.340	PCVX ETNB RYTM AKUS VSTM FMTX ... TGTX RARX PHAT IMRA KALA SCPH THOR STSA EIGRQ ARVN EIDX DRNA GTHX KALV ACRS WVE ACHN SGMO DSCI BSTC ARDMQ SQNM CRIS RXST ABOS VRDN DICE ITRM SLDB ORTX CLYM HOWL ICVX NKTX AVTE ITOS PNT VOR JANX CTKB PEPG TYRA ANTX FULC SBTX ACRV SPRY ELVN MLYS BDTX SEPN CDTX FDMT BOLD JBIO LENZ ARTV BCAX SION
Ra Capital Management, L.p.	2020-09-29	9.750	9.750	22.600	93.150	19.410	-5.900	7.570	18.000	12.560	71.580	4.450	-17.720	PCVX CRDF PMVP DYN ETNB TGTX ... INBX INZY ITOS PAND NKTX RYTM AKUS VSTM FMTX RARX PHAT IMRA KALA SCPH THOR STSA WVE EIGRQ ARVN EIDX DRNA KALV GTHX ACRS ACHN SGMO DSCI BSTC ARDMQ SQNM CRIS RXST ABOS VRDN DICE ITRM SLDB ORTX CLYM HOWL ICVX AVTE PNT VOR JANX CTKB PEPG TYRA ANTX FULC SBTX ACRV SPRY ELVN MLYS BDTX SEPN CDTX FDMT BOLD JBIO LENZ ARTV BCAX SION
Rajeev M. Shah	2020-03-13	10.660	10.660	20.060	35.070	-4.130	-20.240	11.720	1.980	16.270	21.930	-16.880	-31.070	PCVX CRDF PMVP DYN ETNB TGTX ... INBX INZY ITOS PAND NKTX RYTM AKUS KALA VSTM FMTX SLDB STSA EIDX RARX PHAT IMRA SCPH BDTX THOR KALV RXST ABOS VRDN WVE DICE ITRM ORTX CLYM HOWL ICVX AVTE PNT VOR JANX CTKB PEPG TYRA ANTX FULC SBTX ACRV SPRY ELVN MLYS SEPN CDTX FDMT BOLD JBIO LENZ ARTV BCAX SION
Ronald Hunt	2021-08-02	9.170	9.170	-9.840	-11.480	-23.020	-47.410	7.170	33.160	-16.060	-23.080	-30.490	-59.300	ITRM HARP STIM IRTC LITS ARAV ... CMRX CNCE OXFD RLYP PRTK RLYB
Sailaja Puttagunta	2022-12-02	-	-	-	-	-	-	-	-	-	-	-	-	PHGE.U ITRM PHGE
Sarissa Capital Catapult Fund Llc		-	-	-	-	-	-	-	-	-	-	-	-	RGLS ITRM
Sarissa Capital Hawkeye Fund Lp		-	-	-	-	-	-	-	-	-	-	-	-	RGLS ITRM
Sarissa Capital Management Lp		-	-	-	-	-	-	-	-	-	-	-	-	SRSAU RGLS SEELQ VVUSQ IRWD ITRM ... SRSA INVA
Sarissa Capital Master Fund Ii Lp		-	-	-	-	-	-	-	-	-	-	-	-	RGLS ITRM
Sarissa Capital Offshore Master Fund Lp		-	-	-	-	-	-	-	-	-	-	-	-	RGLS SEELQ VVUSQ ITRM
Shahzad Malik	2018-05-30	-12.180	-12.180	-48.400	-44.450	-41.140	-50.800	-11.970	-22.710	-49.730	-46.830	-46.860	-66.380	AFIB ITRM ARAV AXNX HSTOQ AGEN ... EBS
Sofinnova Management Ix, L.l.c.		-	-	-	-	-	-	-	-	-	-	-	-	CMPI ITRM NXTC GRTX ETTX ATYR
Sofinnova Venture Partners Ix, L.p.	2019-11-15	-9.900	-9.900	-9.900	-31.740	-52.440	-48.560	-9.510	-6.150	-8.240	-37.060	-66.790	-60.090	CMPI ITRM NXTC GRTX ETTX ATYR

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