Septerna Inc

NEW
NAS:SEPN (USA)  
$ 38.83 -0.70 (-1.77%) 10:08 PM EST
At Loss
P/B:
4.61
Market Cap:
$ 1.75B
Enterprise V:
$ 1.43B
Volume:
274.14K
Avg Vol (2M):
435.71K
Trade In:
Volume:
274.14K
At Loss
Avg Vol (2M):
435.71K

Business Description

Septerna Inc
NAICS : 541714 SIC : 2834
ISIN : US81734D1046

Total Employee Number:

130
Description
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
Name Current Vs Industry Vs History
Cash-To-Debt
15.05
Equity-to-Asset
0.66
Debt-to-Equity
0.06
Debt-to-EBITDA
-0.35
Interest Coverage
N/A
N/A
N/A
Piotroski F-Score
N/A/9
0
1
2
3
4
5
6
7
8
9
Altman Z-Score
5.69
Distress
Grey
Safe
Beneish M-Score
60.72
Manipulator
Not Manipulator
WACC vs ROIC
WACC
ROIC

Momentum Rank

Name Current Vs Industry Vs History
5-Day RSI
71.54
9-Day RSI
67.05
14-Day RSI
63.01
3-1 Month Momentum %
49.42
6-1 Month Momentum %
41.01
12-1 Month Momentum %
206.24

Liquidity Ratio

Name Current Vs Industry Vs History
Current Ratio
4.71
Quick Ratio
4.71
Cash Ratio
4.44
Days Sales Outstanding
30.56

Dividend & Buy Back

Name Current Vs Industry Vs History
3-Year Average Share Buyback Ratio
-2.2
Shareholder Yield %
-0.1
Name Current Vs Industry Vs History
Operating Margin %
-94.37
Net Margin %
-49.88
EBITDA Margin %
-92.12
FCF Margin %
147.99
OCF Margin %
149.33
ROE %
-9.35
ROA %
-6.87
ROIC %
-38.53
3-Year ROIIC %
-21.21
ROC (Joel Greenblatt) %
-256.48
ROCE %
-14.47
Years of Profitability over Past 10-Year
1
Moat Score
3
Tariff Resilience Score
5

Financials (Next Earnings Date:2026-08-11 Est.)

SEPN's 30-Y Financials
Income Statement Breakdown FY
Not Enough Data
Balance Sheet Breakdown
Not Enough Data
Cashflow Statement Breakdown
Not Enough Data

Operating Revenue by Business Segment

Operating Revenue by Geographic Region

Historical Operating Revenue by Business Segment

Historical Operating Revenue by Geographic Region

5-Step DuPont Analysis as of
Not Enough Data

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Performance

Dividend
Log
Bar
To

Annualized Return %  

Symbol
1 Week
1 Month
3 Months
6 Months
YTD
1 Year
3 Years
5 Years
10 Years

Total Annual Return %  

Symbol
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017

Septerna Inc Executives

Details

GF Valueâ„¢

Valuation Chart

Year:

Analyst Estimate

Key Statistics

Name Value
Revenue (TTM) (Mil $) 72.255
EPS (TTM) ($) -0.81
Beta -
3-Year Sharpe Ratio -
3-Year Sortino Ratio -
Volatility % 77.15
14-Day RSI 63.01
14-Day ATR ($) 2.299769
20-Day SMA ($) 34.8185
12-1 Month Momentum % 206.24
52-Week Range ($) 10.6161 - 40.65
Shares Outstanding (Mil) 45.08

Piotroski F-Score Details

Year:
Component Result
Piotroski F-Score 9999
Positive ROA
Positive CFROA
Higher ROA yoy
CFROA > ROA
Lower Leverage yoy
Higher Current Ratio yoy
Less Shares Outstanding yoy
Higher Gross Margin yoy
Higher Asset Turnover yoy

Septerna Inc Filings

Filing Date Document Date Form
No Filing Data

Septerna Inc Stock Events

Financials Calendars
Event Date Price ($)
Third quarter earnings results for 2026 2026-11-10 In 94 days
Second quarter earnings results for 2026 2026-08-11 In 3 days
General meeting for 2026 2026-06-26 14:00 34.54 (-5.01%)
Bank of America Securities Health Care Conference 2026-05-12 17:00 23.57 (-1.26%)
First quarter earnings results for 2026 2026-05-11 23.87 (-0.46%)
Annual report for 2026 2026-03-09 28.78 (+6.40%)
Fourth quarter earnings results for 2025 2026-03-09 28.78 (+6.40%)
the TD Cowen 46(th) Annual Health Care Conference 2026-03-03 15:10 28.64 (+1.89%)
https://ccdbwebprod.dcc8fc7.eas.morningstar.com/CCDB/Files/648297295.html 2026-03-02 08:00 29.02 (-2.58%)
44(th) Annual J.P. Morgan Healthcare Conference 2026-01-13 15:45 24.88 (-2.39%)
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Septerna Inc Frequently Asked Questions

What is Septerna Inc(SEPN)'s stock price today?
The current price of SEPN is $38.83. The 52 week high of SEPN is $40.65 and 52 week low is $10.62.
When is next earnings date of Septerna Inc(SEPN)?
The next earnings date of Septerna Inc(SEPN) is 2026-08-11 Est..
Does Septerna Inc(SEPN) pay dividends? If so, how much?
Septerna Inc(SEPN) does not pay dividend.

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